Status Hematologi, Kadar IgG dan IgA Tikus yang Mengonsumsi berbagai Variasi Jumlah Tempe Kedelai Hitam

https://doi.org/10.22146/agritech.26118

Nurrahman Nurrahman(1*), Mariyam Mariyam(2)

(1) Program Studi Teknologi Pangan, Universitas Muhammadiyah Semarang, Jl. Kedung Mundu Raya No. 18, Kedungmundu, Kecamatan Tembalang, Kota Semarang, Jawa Tengah, 50273
(2) Program Studi Keperawatan, Universitas Muhammadiyah Semarang, Jl. Kedung Mundu Raya No. 18, Kedungmundu, Kecamatan Tembalang, Kota Semarang, Jawa Tengah, 50273
(*) Corresponding Author

Abstract


Consumption of black soybean tempe can provide rapid improvement in children with poor nutritional status and/or suffering from diarrhea. The antioxidant activity of black soybean tempe is higher than yellow soybean tempe. This study aimed to examine the effect of the amount of black soybean tempe in the feed on hematological status, IgG levels, and IgA levels of rat blood. There was a total of 6 groups, each containing 5 rats. The rats were kept in animal laboratories at room temperature (25–27°C) for 25 days. The six groups were induced Enteropathogenic Escherichia coli (EPEC) suspension with a concentration of 107 CFU / mL of 1 mL per day for seven days, orally using a feeding tube. Parameters analyzed included hematology status, IgG levels and IgA levels. The administration of black soybean tempe had an effect on increasing hemoglobin levels, the number of erythrocytes and the percentage of hematocrit, and it gave the effect of decreasing the number of leukocytes and platelets of rat blood induced with EPEC bacteria. The group of rats that consumed black soybean tempe had no influence on IgG and IgA levels of blood plasma.

Keywords


Black soybean tempe; hematology; IgG; IgA

Full Text:

PDF


References

Abbas, A.K., A.H. Lichtman, and S. Pillai. 2007. Cellular and Molecular Immunology. Saunders Elsevier, Philadelphia.

Astawan, M, T. Wresdiyati, Suliantari, dan Y.MS. Nababan. 2012. Yoghurt sinbiotik berbasis probiotik lokal dapat mencegah diare dan mengubah status hematologi tikus. Jurnal Veteriner, 13(2), 145-153.

Astuti, M. 1996. Tempe dan antoksidan prospek pencegahan penyakit degeneratif. Dalam. Sapuan dan N. Soetrisno (eds.). 1996. Bunga Rampai Tempe Indonesia, Jakarta, hal. 133-146. Yayasan Tempe Indonesia, Jakarta.

Giknis, M.L.A and C.B. Clifford, D.V.M. 2008. Clinical Laoratory Parameters for Crl:WI(Han). Charles River Laboratories, Wilmington.

Nurrahman. (2012). Potensi Tempe Kedelai Hitam dalam meningkatkan Kadar IgA Sekretori dan Proliferasi Limfosit in vivo. Disertasi. Fakultas Teknologi Pertanian UGM, Yogyakarta.

Nurrahman, M. Astuti, Suparmo dan M.H.N.E. Soesatyo. (2011). The effect of black soybeans tempe and it’s ethanol extract on lymphocyte proliferation and IgA secretion in Salmonella typhimurium induced rat. Afri. J. Food Scie., 5(14), 775–779.

Nurrahman, M. Astuti, Suparmo dan M.H.N.E. Soesatyo. (2012a). Pertumbuhan jamur, sifat organoleptik dan aktivitas antioksidan tempe kedelai hitam yang diproduksi dengan berbagai jenis inokulum. J. Agritech, 32(1), 60–65.

Nurrahman, M. Astuti, Suparmo dan M.H.N.E. Soesatyo. (2012b). Peran tempe kedelai hitam dalam meningkatkan aktivitas enzim antioksidan dan daya tahan limfosit terhadap hidrogen peroksida in vivo. Proseding Seminar Hasil-hasil Penelitian UNIMUS, Semarang.

Nurrahaman dan Nurhidajah. (2014). Pengaruh Konsumsi Tempe Kedelai Hitam terhadap Berat Badan Tikus. Proseding Seminar Hasil-hasil Penelitian UNIMUS, Semarang.

Sudigbia, P. 1996. Tempe dalam Penatalaksanaan Diare Anak. Dalam. Sapuan dan N. Soetrisno (eds.). 1996. Bunga Rampai Tempe Indonesia, Jakarta, hal. 71-82. Yayasan Tempe Indonesia, Jakarta.

Xu, B.J. and S.K.S. Chang. (2007). A Comparative study on phenolic profils and antioxidant of legums as affected by extraction solvents. J. Food Sci., 72(2):159-166. DOI: 10.1111/j.1750-3841.2006.00260.x



DOI: https://doi.org/10.22146/agritech.26118

Article Metrics

Abstract views : 3509 | views : 13477

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2019 Nurrahman Nurrahman, Mariyam Mariyam

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

agriTECH has been Indexed by:

Emerging Source Citation Index Directory of Open Access Journals CABI.org Dimensions Google Scholar Sinta Garuda

agriTECH (print ISSN 0216-0455; online ISSN 2527-3825) is published by Faculty of Agricultural Technology, Universitas Gadjah Mada in colaboration with Indonesian Association of Food Technologies.

website statisticsView My Stats