Penghambatan Oksidasi LDL oleh Ekstrak Air Jahe (Zingiber officinale Roscoe) Secara In Vitro

https://doi.org/10.22146/agritech.13575

Aisyah Tri Septiana(1*), Fransiska Rungkat Zakaria(2)

(1) Jurusan Teknologi Pertanian, Fakultas Pertanian, UNSOED, Purwokerto
(2) Program Studi Ilmu Pangan, Teknologi Pertanian, Institut Pertanian Bogor
(*) Corresponding Author

Abstract


Oxidative modification of LDL is believed to play an important role in atherogenesis. Water extract of ginger rhizomes exhibited antioxidative activity is higher than α tocopherol using linoleic acid as substrate. In addition, these extract is kind of ginger extract that daily consumed so may be can be used as functional food. We investigated the effect of in vitro these extract enrichment of LDL on the prevention of oxidative LDL by CuSO4. Plasma was supplemented with 430 or 4300 µg/ml water extract in dimethylsulfoxide (DMSO) (10 µ DMSO per ml plasma), incubated, and the LDL was isolated. Ginger extract also was suplemented on LDL was isolate, and incubated. Lag phase and malonaldehide content was analized after the isolated LDL was oxidized using CuSO4. The result showed that water extract of ginger rhizomes suplementation reduced melonaldehide formation depended on its suplementation. Suplementation these extract on plasma (4300 µg/ml plasma) only reduced 19,04 % malonaldehide content, whereas α tocopherol suplemtation can reduced 26,29 % malonaldehide formation. These extract suplementation on LDL isolate can reduced 43,91 % malonaldehide formation. This research has shown that ginger extract is capable of protecting LDL from oxidation.

Keywords


Ginger (Zinger officinale Roscoe); ginger extract; LDL; lag phase; malonaldehide

Full Text:

PDF



DOI: https://doi.org/10.22146/agritech.13575

Article Metrics

Abstract views : 203 | views : 164

Refbacks

  • There are currently no refbacks.




Copyright (c) 2016 Jurnal Agritech

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

agriTECH has been Indexed by:


agriTECH (print ISSN 0216-0455; online ISSN 2527-3825) is published by Faculty of Agricultural Technology, Universitas Gadjah Mada in colaboration with Indonesian Association of Food Technologies.


website statisticsView My Stats