6,6’-DIMETHOXY-4,4’-DIHYDROXY-3’,2’-FURANO-ISOFLAVANE, A NEW COMPOUND FROM Melochia umbellata (Houtt.) Stapf var. Degrabrata K. (Paliasa)

https://doi.org/10.22146/ijc.21463

Erwin Erwin(1), Alfian Noor(2*), Nunuk Hariani Soekamto(3), Tjodi Harlim(4)

(1) Doctoral Programme in Chemistry, Post Graduate Programme, Hasanuddin University and Department of Chemistry, Mulawarman University, Kampus Gn. Kelua, 75123 Samarinda
(2) Department of Chemistry Hasanuddin University, Kampus UNHAS Tamalanrea, 90245 Makassar
(3) Department of Chemistry Hasanuddin University, Kampus UNHAS Tamalanrea, 90245 Makassar
(4) Department of Chemistry Hasanuddin University, Kampus UNHAS Tamalanrea, 90245 Makassar
(*) Corresponding Author

Abstract


Using data from UV, IR, 1H-NMR, 13C-NMR, dan NMR-2D analysis, a compound of 6,6'-dimethoxy-4,4'-dihydroxy-3',2'-furano-isoflavane (1) was successfully isolated from chloroform fraction of heartwood in Melochia umbellata (Houtt.) Stapf var. Degrabarata K (Paliasa). Hitherto no report of such compound found in literature. The compound however has not shown a significant bioactivity according to either brine shrimp lethality test or evaluation of anti tumor activity against leukemia murine cell (P-388).

Keywords: isoflavane, heartwood, chloroform and Melochia umbellata

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DOI: https://doi.org/10.22146/ijc.21463

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Indonesian Journal of Chemisty (ISSN 1411-9420 / 2460-1578) - Chemistry Department, Universitas Gadjah Mada, Indonesia.

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