STRUCTURE ELUCIDATION OF ALKALOIDS FROM LEAVES OF Voacanga foetida (Bl.) Rolfe OF LOMBOK ISLAND

https://doi.org/10.22146/ijc.21460

Surya Hadi(1*), Dina Asnawati(2), Novi Febrianti(3)

(1) Study Program of Chemistry, Faculty of Mathematics and Natural Sciences, University of Mataram, Jl. Majapahit 62 Mataram-NTB 83125
(2) Study Program of Chemistry, Faculty of Mathematics and Natural Sciences, University of Mataram, Jl. Majapahit 62 Mataram-NTB 83125
(3) Study Program of Biology, Faculty of Mathematics and Natural Sciences, University of Mataram, Jl. Majapahit 62 Mataram-NTB 83125
(*) Corresponding Author

Abstract


The leaves of Voacanga foetida (Bl.) Rolfe, have been used ethnomedically for the treatment of wounds, itches, and swellings particularly in Lombok island. A phytochemical study has been done to investigate chemical compounds responsible against the cause of the diseases. By separating alkaloidal fraction from the leaves was found voacristine 1 as the major alkaloidal compound, and voacangine 2 and coronaridine 3 as the minor components. The structure elucidation of the compounds was carried out on the basis of spectroscopy data. A structure revision of voacristine 1 was also reported.


Keywords


alkaloids; Voacanga foetida; Lombok

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DOI: https://doi.org/10.22146/ijc.21460

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