STRUCTURE ELUCIDATION OF ANTIBACTERIAL COMPOUND FROM Ficus deltoidea Jack LEAVES

https://doi.org/10.22146/ijc.21422

Suryati Suryati(1*), Hazli Nurdin(2), Dachriyanus Dachriyanus(3), Md Nordin Hj Lajis(4)

(1) Politechnic, Andalas University, Padang
(2) Faculty of Mathematics and Natural Science, Andalas University, Padang
(3) Faculty Pharmacy, Andalas University, Padang
(4) Institute of BioScience, University Putra Malaysia
(*) Corresponding Author

Abstract


An antibacterial compound has been isolated from Ficus deltoidea Jack leaves. Based on spectroscopic data (IR, 1H-NMR, 13C NMR 1D and 2D and MS), the structure of this compound was identified as 3β-hydroksilup-20(29)-en, (lupeol), C30H50O. This compound showed antibacterial activities against E. coli, B. subtilis and S. aureus. The minimum inhibition concentration (MIC) against E. coli, B. subtilis and S. aureus are 150, 220 and 130 μg/mL respectively.

Keywords


Antibacterial activity; Ficus deltoidea Jack; lupeol

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DOI: https://doi.org/10.22146/ijc.21422

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Indonesian Journal of Chemisty (ISSN 1411-9420 / 2460-1578) - Chemistry Department, Universitas Gadjah Mada, Indonesia.

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