IRON CHELATING AND ANTIRADICAL ACTIVITY OF KAYU MANIK LEAVES (Trema orientalis)

https://doi.org/10.22146/ijc.21410

Salprima Yudha S.(1*), Eka Angasa(2), Sri Ningsih(3), Syalfinaf Manaf(4), Suli Anggria Murni(5), Fatan Umbara(6)

(1) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(2) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(3) Agency for the Assessment and Application of Technology, Gedung BPPT, Jl. MH. Thamrin 8, Jakarta 10340
(4) Department of Biology, University of Bengkulu, Jl. Raya Kandang Limun Bengkulu 38371A
(5) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(6) Laboratory of Bioinorganic Chemistry, Department of Chemistry, University of Bengkulu (UNIB), Jl. Raya Kandang Limun Bengkulu 38371A
(*) Corresponding Author

Abstract


A methanol soluble fraction extracted from Kayu Manik leaves (Trema orientalis) from Seluma, Bengkulu, exhibited an antiradical activity 69.73% (scavenging activity of the stable 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical) that was almost similar to that of 1 mM ascorbic acid. On the other hand, the iron chelating activity was 40.74%. We believe that it would be useful to take the results as an alternative for processing industries and can be observed as a good source of new agent for iron chelator.

Keywords


Antiradical; Flavonoid; Iron chelating; Kayu Manik Leaves; Thalasemia

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References

[1] Tepe, B., Sokmen, M., Akpulat, H. A., and Sokmen, A., 2005, Food Chem., 90, 4, 685–689.

[2] Auroma, O.I., 1998, J. Am. Oil Chem. Soc. 75, 199–212.

[3] Takao, T., Kiatani, F., Watanabe, N., Yagi, A., and Sakata, K., 1994, Biosci. Biotech. Biochem, 58, 1780–1783.

[4] Pietta, P-G., 2000, J. Nat. Prod., 63, 7, 1035–1042.

[5] Chu, Y.H., Chang, C.L., and Hsu, H.F., 2000, J. Sci. Food Agric., 80, 561–566.

[6] Yuan, Y.V., Bone, D.E., and Carrington, M.F., 2005, Food Chem., 91, 485–494.

[7] Nagai, T., Myoda, T., and Nagashima, T., 2005, Food Chem., 91, 389–394.

[8] Baardseth, P., 1989, Food Addit. Contam., 6, 2, 201–207.

[9] Yu, B.P., 1994, Physiol. Rev., 74, 1, 139–162.

[10] Ebrahimzadeh, M.A., Pourmorad, F., and Bekhradnia, A.R., 2008, Afr. J. Biotechnol., 7, 18, 3188–3192.

[11] Poumorrad, F., Hosseinimehr, S.J., and Shahabimajd, N., 2006, Afr. J. Biotechnol., 5, 11, 1142–1145.

[12] Aboul-Enein, A.M., El Baz, F.K., El-Baroty, G.S., Youssef, A.M., and El-Baky, A.H.H., 2003, J. Med. Sci., 3, 87–98.

[13] Cappelini, M.D., 2005, Best Pract. Res. Clin. Haematol., 18, 2, 289–298.

[14] Tchamo, D.N., Cartier, G., Dijoux-Franca, M.G. Tsamo, E., and Mariotte, A.M., 2001, Pharm. Biol., 39, 3, 202–205.

[15] Chang, C-C, Yang, M-H, When, H-W, and Chern, J-C., 2002, J. Food Drug Anal., 10, 3, 178–182.

[16] Okada, Y., and Okada, M., 1998, J. Agric. Food Chem., 46, 401–406.

[17] Dinis, T.C.P., Madeira, V.M.C., and Almeida, M.L.M., 1994, Arch. Biochem. Biophys., 315, 161–169.

[18] Afanaslejev, 1989, Biochem. Pharmacol., 38, 1763–1769.

[19] Wen-Lung, K., Yu-Ling, H., Shr-Ting, W., Ching-Li, N., Bor-Jinn, S., and Chien-Chih, C., 2007, J. Chin. Med., 8, 1-2, 27–36.

[20] McCord, J.M., 2000, Am. J. Med., 108, 652–659.

[21] Al-Mamary, M., Al-Meeri, A., and Al-Habori, M., 2002, Nutr. Res., 22, 9, 1041–1047.

[22] Frankel, E.N., and Meyer, A.S., 2000, J. Sci. Food Agric., 80, 1925–1941.

[23] Brittenham, G.M., 2003, Alcohol, 30, 2, 151–158.

[24] Viuda-Martos, M., Navajas, Y.R.; Zapata, E.S., Fernandez-Lopez, J., and Perez-Alvarez, J.A., 2010, Flavour Fragance J., 25, 13–19.

[25] Deshpande, S.S., Deshpande, U.S., and Salunkhe, D.K., in Food Antioxidants: Technological, Toxicological and Health Perspectives, Madhavi, D.L., Deshpande, S.S., and Salunkhe D.K., (eds). Marcel Dekker: New York, 1995, 361.



DOI: https://doi.org/10.22146/ijc.21410

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