Synthesis, Reactivity and Stability of Aryl Halide Protecting Groups towards Di-Substituted Pyridines

https://doi.org/10.22146/ijc.21177

Ptoton Mnangat Brian(1*), Peter Musau(2)

(1) Department of Chemistry, Muranga University College, P.O. Box 75-10200, Muranga
(2) Department of Chemistry, South Eastern University College, P.O. Box 170-90200 Kitui
(*) Corresponding Author

Abstract


This paper reports the synthesis and reactivity of different Benzyl derivative protecting groups. The synthesis and stability of Benzyl halides, 4-methoxybenzyl halides, 3,5-dimethoxybenzyl halides, 3,4-dimethoxybenzyl halides, 3,4,5-trimethoxybenzyl halide protecting groups and their reactivity towards nitrogen atom of a di-substituted pyridine ring in formation of pyridinium salts is also reported.

Keywords


aryl halide protecting groups; benzyl halides; 4-methoxybenzyl halide; 3,5-dimethoxybenzyl halide; 3,4-dimethoxybenzyl halide

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DOI: https://doi.org/10.22146/ijc.21177

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