Bowman's Gland in Nasal Tissues: As A Possible

https://doi.org/10.22146/jifnp.68

Hastari Wuryastuti(1*), R. Wasito(2)

(1) Gadjah Mada University
(2) Gadjah Mada University
(*) Corresponding Author

Abstract


We have investigated the Bowman's gland of the nasal cavity after in vivo study in the Sprague-Dawley rats to asses its biomarker potential in vitamin A nutritional study. Fourty-eight male weanling SpragueDawley rats at 3-4 weeks of age were allotted to four groups of 12 each and were fed diets either vitamin A-deficient or supplemented with 30.000 IU vitamin A/kg for 150 days. Rats in their respective groups were also given fume of vehicle for 150 days. Fumigation was done 2x/day for 1 hour each. Rats given vitamin A-deficient diet and fume of vehicle had the most extensive inhibition of glycoprotein synthesis in cells of Bowman's gland in the olfactory region of the nasal cavities as determined by severe loss of Alcian blue-periodic acid-Schiff staining material. Histochemical lesions were not seen in nasal cavity of vitamin A-supplemented rats

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DOI: https://doi.org/10.22146/jifnp.68

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Indonesian Food and Nutrition Progress (print ISSN 0854-6177, online ISSN 2597-9388) is published by the Indonesian Association of Food Technologist in collaboration with Department of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Gadjah Mada.

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