The Development of Plant-Based Jelly Candy for Chrysanthemum indicum L. Flower Extract and Evaluation of The Antioxidant Activity

  • Qesiana Afjani Nur Baiti Undergraduate Program, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia, 55281
  • Zahra Salsabila Undergraduate Program of Pharmacy, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia, 55281
  • Wimala Apsari Undergraduate Program of Pharmacy, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia, 55281
  • Muhammad Bintang Ramadan Undergraduate Program of Pharmacy, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia, 55281
  • Eugenia Karen 2Undergraduate Program, Faculty of Agricultural Technology, Gadjah Mada University, Jalan Flora, Bulaksumur, Depok, Sleman, Yogyakarta 55281, Indonesia
  • Valencia 2Undergraduate Program, Faculty of Agricultural Technology, Gadjah Mada University, Jalan Flora, Bulaksumur, Depok, Sleman, Yogyakarta 55281, Indonesia
  • Muhammad Novrizal Abdi Sahid Department of Pharmaceuticals Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia, 55281
  • Cici Darsih 3 Pusat Riset Teknologi dan Proses Pangan, Badan Riset dan Inovasi Nasional, Gunung Kidul, Daerah Istimewa Yogyakarta, 55861
  • Marlyn D Laksitorini
Keywords: Chrysanthemum indicum, Antioxidant, Jelly candy, Glucomannan, Kappa-Carrageenan


Increasing awareness of wellness in society increased the demand for health supplements. Free radicals negatively impact vital organs resulting to the progression of neurodegenerative and cardiovascular disease. Herbal medicine such as (Chrysanthemum indicum L.) flowers has been reported to have strong antioxidant effects. However, the available product for Chrysanthemum is tea and capsules which is considered old fashion for many consumers. To improve consumer acceptance, Chrysanthemum can be formulated as jelly candy. However, application of the heat during jelly candy production potentially reduced its antioxidant activities. This research is aimed to develop a Chystanthemum jelly candy that can retain its antioxidant activity. Chrysanthemum flower extract is formulated into a jelly candy using plant-based gelling agents namely glucomannan and kappa carrageenan. Eight formulas were designed according to Design Expert software. Jelly candy’s physical characteristics such as organoleptic, weight uniformity, elasticity, and moisture content were assessed. An antioxidant assay using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method was performed on Chrysanthemum flower extract before and after jelly candy formulation. The optimum formula identified from this study has a composition of kappa carrageenan 1.327% and glucomannan 0.673%. Assessment of antioxidant activity suggested that the jelly candy can retain its antioxidant activity compared to crude extract. The optimum formula exhibited strong antioxidant activity with an IC50 value of 72.91 ± 3.36 µg/mL. Through a minimal heating process, this study suggested that retaining antioxidant activity post-manufacturing process is feasible.


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How to Cite
Baiti, Q. A. N., Salsabila, Z., Apsari, W., Ramadan, M. B., Karen, E., Valencia, Sahid, M. N. A., Darsih, C., & Laksitorini, M. D. (2024). The Development of Plant-Based Jelly Candy for Chrysanthemum indicum L. Flower Extract and Evaluation of The Antioxidant Activity. Indonesian Journal of Pharmacy, 35(2), 292–304.
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