Evaluation of Factors Associated with Beliefs About Antidiabetic Medicine in Outpatients with Type 2 Diabetes at Hue University Hospital

  • Chuyen Le Hue university of medicine and pharmacy, Hue university
  • Thi Minh Hoa Nguyen
  • Thi Kim Cuc Ngo Hue University of Medicine and Pharmacy, Hue University https://orcid.org/0000-0003-2451-4922
  • Thi Thuy Nhi Tran Lam Dong medical college, Lam Dong
Keywords: Beliefs about medicines, medication adherence, type 2 diabetes mellitus, antidiabetic medicine


Poor adherence to antidiabetic medication, which causes diabetes-related complications and increases medical burden, has been an important concern for both patients and physicians. Enhancing patients' beliefs about medicine can partially improve their non-adherence status to medications. To evaluate the factors associated with beliefs about antidiabetic medicine in outpatients with type 2 diabetes at Hue University Hospital. A cross-sectional study was conducted on 396 outpatients diagnosed with type 2 diabetes mellitus at the Endocrinology Clinic at Hue University Hospital. We interviewed the patients using a questionnaire based on the Vietnamese version of the Beliefs about Medicines Questionnaire (BMQ-V). The study was conducted on 396 patients with type 2 diabetes, with a median age of 66.9 ± 13.7 years. The prevalence of outpatients achieving HbA1C and glycemic targets was 18.7% and 20.7%, respectively. According to the BMQ-V questionnaire, the participants’ beliefs about medicine had a mean score of 50.3 ± 8.1. The mean value of the Specific-Concerns subscale was the highest (14.5 ± 3.8) and the Specific-Necessity subscale was the lowest (9.8 ± 3.9). Multivariate regression analysis revealed a statistically significant association between BMQ score and HbA1c control status, duration of diabetes, and home blood glucose monitoring (p < 0.05). Coordination between clinical pharmacists and physicians should be strengthened to improve their positive beliefs and gradually reduce their negative beliefs about medicines, thereby increasing medication adherence and improving treatment effectiveness.


ADA. (2020). Standards of medical care in diabetes. 45, 270.
American Diabetes Association. (2015). Standards of medical care in diabetes. 45.
Anghel, L. A., Farcas, A. M., & Oprean, R. N. (2019). An overview of the common methods used to measure treatment adherence. Medicine and Pharmacy Reports. https://doi.org/10.15386/mpr-1201
Gatti, M. E., Jacobson, K. L., Gazmararian, J. A., Schmotzer, B., & Kripalani, S. (2009). Relationships between beliefs about medications and adherence. American Journal of Health-System Pharmacy, 66(7), 657–664. https://doi.org/10.2146/ajhp080064
Horne, R., Weinman, J., & Hankins, M. (1999). The beliefs about medicines questionnaire: The development and evaluation of a new method for assessing the cognitive representation of medication. Psychology & Health, 14(1), 1–24. https://doi.org/10.1080/08870449908407311
IDF. (2017). IDF DIABETES ATLAS. https://diabetesatlas.org/upload/resources/previous/files/8/IDF_DA_8e-EN-final.pdf
Jimenez, K., Vargas, C., Garcia, K., Guzman, H., Angulo, M., & Billimek, J. (2017). Evaluating the Validity and Reliability of the Beliefs About Medicines Questionnaire in Low-Income, Spanish-Speaking Patients With Diabetes in the United States. The Diabetes Educator, 43(1), 114–124. https://doi.org/10.1177/0145721716675740
Khdour, M. R., Awadallah, H. B., Alnadi, M. A., & Al-Hamed, D. H. (2020). Beliefs About Medicine and Glycemic Control Among Type 2 Diabetes Patients: A Cross-Sectional Study in West Bank, Palestine. Journal of Primary Care & Community Health, 11, 215013272097191. https://doi.org/10.1177/2150132720971919
Lavsa, S. M., Holzworth, A., & Ansani, N. T. (2011). Selection of a validated scale for measuring medication adherence. Journal of the American Pharmacists Association, 51(1), 90–94. https://doi.org/10.1331/JAPhA.2011.09154
Le T. H. G., & Ha V. N.. (2013). Status and some factors related to medication adherence for type 2 diabetes of outpatients at the 198 hospital in 2013. Journal of practical medicine, 11, 93-97.
Management of diabetes: A national clinical guideline. (2010). Scottish Intercollegiate Guidelines Network.
Ngo V. M., & Bui T. D. H.. (2021). Belief about the medicine of type 2 diabetes outpatients at Thai Binh Medical University Hospital in 2020. Vietnam Journal of Preventive Medicine, 31(8), 40–47.
Nguyen, T., Cao, H. T. K., Quach, D. N., Le, K. K., Au, S. X., Pham, S. T., Nguyen, T. H., Pham, T. T., & Taxis, K. (2019). The Vietnamese Version of the Brief Illness Perception Questionnaire and the Beliefs about Medicines Questionnaire: Translation and Cross‐cultural Adaptation. Tropical Medicine & International Health, 24(12), 1465–1474. https://doi.org/10.1111/tmi.13312
Polonsky, W., & Henry, R. (2016). Poor medication adherence in type 2 diabetes: Recognizing the scope of the problem and its key contributors. Patient Preference and Adherence, Volume 10, 1299–1307. https://doi.org/10.2147/PPA.S106821
Raza, S., Iqbal, Q., Haider, S., Khalid, A., Hassali, M. A., & Saleem, F. (2020). Beliefs about medicines among type 2 diabetes mellitus patients in Quetta city, Pakistan: A cross-sectional assessment. Journal of Public Health, 28(3), 277–283. https://doi.org/10.1007/s10389-019-01046-8
Sirey, J. A., Greenfield, A., Weinberger, M. I., & Bruce, M. L. (2013). Medication Beliefs and Self-Reported Adherence Among Community-Dwelling Older Adults. Clinical Therapeutics, 35(2), 153–160. https://doi.org/10.1016/j.clinthera.2013.01.001
Supramaniam, P., binti Ali, A., Li Yun, C., Pei Yi, C., binti Shaari, A., binti Kamaruzaman, N. H., Jia Yi, S., Keat Ming, T., Yuan Liang, W., & Pei Wen, Y. (2019). Reliability and validity of Beliefs on Medicine Questionnaire (BMQ) in diabetes mellitus patients: Malay Translated Version. International Journal of Scientific and Research Publications (IJSRP), 9(2), p8609. https://doi.org/10.29322/IJSRP.9.02.2019.p8609
Sweileh, W. M., Zyoud, S. H., Abu Nab’a, R. J., Deleq, M. I., Enaia, M. I., Nassar, S. M., & Al-Jabi, S. W. (2014). Influence of patients’ disease knowledge and beliefs about medicines on medication adherence: Findings from a cross-sectional survey among patients with type 2 diabetes mellitus in Palestine. BMC Public Health, 14(1), 94. https://doi.org/10.1186/1471-2458-14-94
How to Cite
Le, C., Nguyen, T. M. H., Ngo, T. K. C., & Tran, T. T. N. (2023). Evaluation of Factors Associated with Beliefs About Antidiabetic Medicine in Outpatients with Type 2 Diabetes at Hue University Hospital. Indonesian Journal of Pharmacy, 34(4), 675-685. https://doi.org/10.22146/ijp.6871
Research Article