Synthesis and Biological Activity Study of Co and Cr Complexes with α-(2-Salsayl)-N-phenyl Nitrone and Oxide Nanoparticles

https://doi.org/10.22146/ijc.77276

Dhamiaa Abdul-Shaheed Issa(1), Hayder Baqer Abdullah(2), Faeza Abdulkareem Al-Mashal(3*)

(1) Department of Chemistry, College of Education for Pure Science, University of Basrah, 61004 Basrah, Iraq
(2) Department of Chemistry, College of Education for Pure Science, University of Basrah, 61004 Basrah, Iraq
(3) Department of Chemistry, College of Education for Pure Science, University of Basrah, 61004 Basrah, Iraq
(*) Corresponding Author

Abstract


This paper describes the synthesis of two complexes from the ligand α-(2-Salsayl)-N-phenyl nitrone with CoCl2 and CrCl2. The ligand was characterized by several spectroscopic techniques (ultraviolet/visible (UV/Vis), nuclear magnetic resonance (1H-NMR and 13C-NMR), Fourier-transform infrared spectroscopy (FTIR), and mass spectrometry (MS). While infrared, ultraviolet-visible (UV-Vis), thermal analysis, and job method studies were used to reveal the structure of the complexes. The synthesized complexes were then synthesized by the sonochemical method, and the copper and chromium oxide nanoparticles were produced using the thermal decomposition method. Scanning electron microscopy (SEM), Energy dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) characterization confirmed the formation of Co3O4 and Cr2O3 nanoparticles. Antimicrobial studies of the complexes against some microorganisms, such as Staphylococcus epidermis and Escherichia coli, utilizing the disk diffusion method, revealed the antibacterial activity of the complexes.

Keywords


nitrones; complex; nanoparticles; biological activity



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DOI: https://doi.org/10.22146/ijc.77276

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