Recent Advances and Future Prospects of Molecular Imprinting Polymers as a Recognition Sensing System for Food Analysis: A Review

Almajed Asaad Abdullah Sfoog(1), Norlaili Abu Bakar(2*), Nurulsaidah Abdul Rahim(3), Wan Rusmawati Wan Mahamod(4), Norhayati Hashim(5), Siti Kamilah Che Soh(6)

(1) Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim, Perak, Malaysia
(2) Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim, Perak, Malaysia
(3) Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim, Perak, Malaysia
(4) Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim, Perak, Malaysia
(5) Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim, Perak, Malaysia; Nanotechnology Research Center, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
(6) Faculty of Science and Marine Environmental, Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, Malaysia
(*) Corresponding Author


Molecular imprinting polymers (MIPs) have been widely used to produce stable polymeric materials due to their highly selective binding sites to determine the analyte (target molecule) in food products. MIPs begin with a complex compound between the template molecule and the functional monomers that can be polymerized when there is a closely crossed link. MIPs left specific cavities after the removal of templates during washing, which complements the size and shape of the templates. The use of MIPs has contributed to novel advances in materials science, polymer science, natural science, and other multi-disciplinary systems. Optical chemical sensor is an exciting field in MIPs today due to comprehend the unique affirmation limit of associated polymers giving stable polymers with high molecular recognition capabilities. MIPs display a wide extent of relevance, incredible flexibility, security, and high selectivity; their internal affirmation districts can be explicitly gotten together with design molecules to achieve specific affirmation. This review covers the various achievements of sensors used in laboratory analyses. The advancement in the development of MIPs is evaluated with an accentuation on the preparation principle, the discovery process, the molecular recognition mechanism and future perspectives and challenges for MIPs in building an optical chemical sensor.


molecularly imprinted polymer; optical chemical sensor; fluorescence sensor; food analysis; molecular recognition

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[1] BelBruno, J.J., 2018, Molecularly imprinted polymers, Chem. Rev., 119 (1), 94–119.

[2] Saylan, Y., Yilmaz, F., Özgür, E., Derazshamshir, A., Yavuz, H., and Denizli, A., 2017, Molecular imprinting of macromolecules for sensor applications, Sensors, 17 (4), 898.

[3] Nagy-Szakolczai, A., Dorkó, Z., Tóth, B., and Horvai, G., 2018, New methods to study the behavior of molecularly imprinted polymers in aprotic solvents, Polymers, 10 (9), 1015.

[4] Li, Z., Wang, Y., Liu, Z., Xie, C., Peng, D., and Yuan, Z., 2020, Selective solid-phase extraction of sulfonamides from edible swine tissues using high-performance imprinted polymers, Food Anal. Methods, 13 (6), 1304–1313.‏

[5] Amatatongchai, M., Thimoonnee, S., Jarujamrus, P., Nacapricha, D., and Lieberzeit, P.A., 2020, Novel amino-containing molecularly-imprinted polymer coating on magnetite-gold core for sensitive and selective carbofuran detection in food, Microchem. J., 158, 105298.

[6] Huang, Z., Zhang, Z., Xia, Q., Li, C., and Yun, Y., 2017, Surface molecularly imprinted polymer microspheres based on nano‐TiO2 for selective recognition of kaempferol, J. Appl. Polym. Sci., 134 (23), 44888.

[7] Jalilian, R., Shahmari, M., Taheri, A., and Gholami, K., 2020, Ultrasonic-assisted micro solid phase extraction of arsenic on a new ion-imprinted polymer synthesized from chitosan-stabilized pickering emulsion in water, rice and vegetable samples, Ultrason. Sonochem., 61, 104802.

[8] Hashemi Orimi, S.M., Khavarpour, M., and Kazemi, S., 2020, Removal of bisphenol A from water solution using molecularly imprinted nanopolymers: Isotherm and kinetic studies, J. Water Environ. Nanotechnol., 5 (1), 56–67.

[9] He, J.X., Pan, H.Y., Xu, L., and Tang, R.Y., 2021, Application of molecularly imprinted polymers for the separation and detection of aflatoxin, J. Chem. Res., 45 (5-6), 400–410.‏

[10] Luliński, P., 2017, Molecularly imprinted polymers based-drug delivery devices: A way to application in modern pharmacotherapy. A review, Mater. Sci. Eng., C, 76, 1344–1353.

[11] Rico-Yuste, A., and Carrasco, S., 2019, Molecularly imprinted polymer-based hybrid materials for the development of optical sensors, Polymers, 11 (7), 1173.

[12] Sun, L., Guan, J., Xu, Q., Yang, X., Wang, J., and Hu, X., 2018, Synthesis and applications of molecularly imprinted polymers modified TiO2 nanomaterials: A review, Polymers, 10 (11), 1248.

[13] Li, J., Huang, X., Ma, J., Wei, S., and Zhang, H., 2020, A novel electrochemical sensor based on molecularly imprinted polymer with binary functional monomers at Fe-doped porous carbon decorated Au electrode for the sensitive detection of lomefloxacin, Ionics, 26 (8), 4183–4192.

[14] Moein, M.M., Abdel-Rehim, A., and Abdel-Rehim, M., 2019, Recent applications of molecularly imprinted sol-gel methodology in sample preparation, Molecules, 24 (16), 2889.

[15] Di Masi, S., Pennetta, A., Guerreiro, A., Canfarotta, F., De Benedetto, G.E., and Malitesta, C., 2020, Sensor based on electrosynthesised imprinted polymeric film for rapid and trace detection of copper (II) ions, Sens. Actuators, B, 307, 127648.‏

[16] Li, D., He, Q., He, Y., Xin, M., Zhang, Y., and Shen, Z., 2017, Molecular imprinting sensor based on quantum weak measurement, Biosens. Bioelectron., 94, 328–334.

[17] Refaat, D., Aggour, M.G., Farghali, A.A., Mahajan, R., Wiklander, J.G., Nicholls, I.A., and Piletsky, S.A., 2019, Strategies for molecular imprinting and the evolution of MIP nanoparticles as plastic antibodies—Synthesis and applications, Int. J. Mol. Sci., 20 (24), 6304.

[18] Ayankojo, A.G., Reut, J., Ciocan, V., Öpik, A., and Syritski, V., 2020, Molecularly imprinted polymer-based sensor for electrochemical detection of erythromycin, Talanta, 209, 120502.

[19] Güney, S., and Güney, O., 2016, A novel electrochemical sensor for selective determination of uranyl ion based on imprinted polymer sol–gel modified carbon paste electrode, Sens. Actuators, B, 231, 45–53.

[20] Marć, M., 2019, Mip Synthesis, Characteristics and Analytical Application, 1st Ed., Elsevier, Amsterdam.

[21] Thongchai, W., Poolprasert, P., and Thongchai, S., 2021, The synthesis of molecularly imprinted polymers on microcentrifuge tube filters for solid-phase extraction and the HPLC-UV determination of andrographolides, J. Chromatogr. Sci., 59 (9), 877–886.‏

[22] Song, X., Turiel, E., He, L., Martín-Esteban, A., 2020, Synthesis of molecularly imprinted polymers for the selective extraction of polymyxins from environmental water samples, Polymers, 12 (1), 131.‏

[23] Herrera-Chacón, A., Cetó, X., and del Valle, M., 2021, Molecularly imprinted polymers-towards electrochemical sensors and electronic tongues, Anal. Bioanal. Chem., 413 (24), 6117–6140.‏

[24] Jamieson, O., Mecozzi, F., Crapnell, R.D., Battell, W., Hudson, A., Novakovic, K., Sachdeva, A., Canfarotta, F., Herdes, C., Banks, C.E., Snyder, H., and Peeters, M., 2021, Approaches to the rational design of molecularly imprinted polymers developed for the selective extraction or detection of antibiotics in environmental and food samples, Phys. Status Solidi A, 218 (13), 2100021.

[25] Zaidi, S.A., 2017, Molecular imprinting polymers and their composites: A promising material for diverse applications, Biomater. Sci., 5 (3), 388–402.

[26] Kutner, W., and Sharma, P.S., 2018, Molecularly Imprinted Polymers for Analytical Chemistry Applications, The Royal Society of Chemistry, Piccadilly, London.

[27] Ramanavicius, S., Jagminas, A., and Ramanavicius, A., 2021, Advances in molecularly imprinted polymers based affinity sensors (Review), Polymers, 13 (6), 974.‏

[28] El-Akaad, S., Mohamed, M.A., Abdelwahab, N.S., Abdelaleem, E.A., De Saeger, S., and Beloglazova, N., 2020, Capacitive sensor based on molecularly imprinted polymers for detection of the insecticide imidacloprid in water, Sci. Rep., 10 (1), 14479.‏

[29] Wang, L., Wen, L., Zhao, L., Chao, J., Tao, F., Wang, F., and Li, C., 2022, Development of fluorescence sensor and test paper based on molecularly imprinted carbon quantum dots for spiked detection of domoic acid in shellfish and lake water, Anal. Chim. Acta, 1197, 339515.‏

[30] Yang, W., Ma, Y., Sun, H., Huang, C., and Shen, X., 2022, Molecularly imprinted polymers based optical fiber sensors: A review, TrAC, Trends Anal. Chem., 152, 116608.

[31] Pesavento, M., Zeni, L., De Maria, L., Alberti, G., and Cennamo, N., 2021, SPR-optical fiber-molecularly imprinted polymer sensor for the detection of furfural in wine, Biosensors, 11 (3), 72.‏

[32] Fang, L., Jia, M., Zhao, H., Kang, L., Shi, L., Zhou, L., and Kong, W., 2021, Molecularly imprinted polymer-based optical sensors for pesticides in foods: Recent advances and future trends, Trends Food Sci. Technol., 116, 387–404.‏

[33] Regasa, M.B., Soreta, T.R., Femi, O.E., Ramamurthy, P.C., and Kumar, S., 2020, Molecularly imprinted polyaniline molecular receptor–based chemical sensor for the electrochemical determination of melamine, J. Mol. Recognit., 33 (7), e2836.‏

[34] Leibl, N., Haupt, K., Gonzato, C., and Duma, L., 2021, Molecularly imprinted polymers for chemical sensing: A tutorial review, Chemosensors, 9 (6), 123.‏

[35] Zhang, M., Yang, Y., Wang, Y., Zhang, B., Wang, H., Fang, G., and Wang, S., 2022, A molecularly imprinted electrochemical sensor based on cationic intercalated two-dimensional titanium carbide nanosheets for sensitive and selective detection of triclosan in food samples, Food Control, 132, 108532.‏

[36] Crapnell, R.D., Hudson, A., Foster, C.W., Eersels, K., van Grinsven, B., Cleij, T.J., Banks, C.E., and Peeters, M., 2019, Recent advances in electrosynthesized molecularly imprinted polymer sensing platforms for bioanalyte detection, Sensors, 19 (5), 1204.‏

[37] Zhou, S., Liu, C., Lin, J., Zhu, Z., Hu, B., and Wu, L., 2022, Towards Development of molecularly imprinted electrochemical sensors for food and drug safety: Progress and trends, Biosensors, 12 (6), 369.‏

[38] Vahid, B., 2017, Specific fluorescence probe for direct recognition of dimethoate using molecularly imprinting polymer on ZnO quantum dots, J. Fluoresc., 27 (4), 1339–1347.

[39] Rutkowska, M., Płotka-Wasylka, J., Morrison, C., Wieczorek, P.P., Namieśnik, J., and Marć, M., 2018, Application of molecularly imprinted polymers in analytical chiral separations and analysis, TrAC, Trends Anal. Chem., 102, 91–102.

[40] Li, Z., Chen, L., Su, Q., Wu, L., Wei, X., Zeng, L., and Li, M., 2019, Synthesis and characterization of a surface-grafted Pb(II)-imprinted polymer based on activated carbon for selective separation and pre-concentration of Pb(II) ions from environmental water samples, RSC Adv., 9 (9), 5110–5120.

[41] Ma, Y., Dai, J., Wang, L., Yan, Y., and Gao, M., 2020, Fabrication of porous molecularly imprinted polymer using halloysite nanotube as template for selective recognition and separation of chloramphenicol, J. Iran. Chem. Soc., 17 (3), 555–565.

[42] Bagheri, A.R., Arabi, M., Ghaedi, M., Ostovan, A., Wang, X., Li, J., and Chen, L., 2019, Dummy molecularly imprinted polymers based on a green synthesis strategy for magnetic solid-phase extraction of acrylamide in food samples, Talanta, 195, 390–400.

[43] Sun, X., Wang, M., Peng, J., Yang, L., Wang, X., Wang, F., Zhang, X., Wu, Q., Chen, R., and Chen, J., 2019, Dummy molecularly imprinted solid phase extraction of climbazole from environmental water samples, Talanta, 196, 47–53.

[44] Azizi, A., Shahhoseini, F., and Bottaro, C.S., 2020, Magnetic molecularly imprinted polymers prepared by reversible addition fragmentation chain transfer polymerization for dispersive solid phase extraction of polycyclic aromatic hydrocarbons in water, J. Chromatogr. A, 1610, 460534.

[45] Wackerlig, J., and Lieberzeit, P.A., 2015, Molecularly imprinted polymer nanoparticles in chemical sensing – Synthesis, characterisation and application, Sens. Actuators, B, 207, 144–157.

[46] Anirudhan, T.S., Deepa, J.R., and Binussreejayan, B., 2018, Electrochemical sensing of cholesterol by molecularly imprinted polymer of silylated graphene oxide and chemically modified nanocellulose polymer, Mater. Sci. Eng., C, 92, 942–956.

[47] Abdin, M.J., Altintas, Z., and Tothill, I.E., 2015, In silico designed nanoMIP based optical sensor for endotoxins monitoring, Biosens. Bioelectron., 67, 177–183.

[48] Ensafi, A.A., Nasr-Esfahani, P., Rezaei, B., 2017, Simultaneous detection of folic acid and methotrexate by an optical sensor based on molecularly imprinted polymers on dual-color CdTe quantum dots, Anal. Chim. Acta, 996, 64–73.

[49] Ensafi, A.A., Nasr-Esfahani, P., and Rezaei, B., 2018, Synthesis of molecularly imprinted polymer on carbon quantum dots as an optical sensor for selective fluorescent determination of promethazine hydrochloride, Sens. Actuators, B, 257, 889–896.

[50] Marcelo, G., Ferreira, I.C., Viveiros, R., and Casimiro, T., 2018, Development of itaconic acid-based molecular imprinted polymers using supercritical fluid technology for pH-triggered drug delivery, Int. J. Pharm., 542 (1-2), 125–131.

[51] Korde, B.A., Mankar, J.S., Phule, S., and Krupadam, R.J., 2019, Nanoporous imprinted polymers (nanoMIPs) for controlled release of cancer drug, Mater. Sci. Eng., C, 99, 222–230.

[52] Bhawani, S.A., Sen, T.S., and Ibrahim, M.N.M., 2018, Synthesis of molecular imprinting polymers for extraction of gallic acid from urine, Chem. Cent. J., 12 (1), 19.‏

[53] Lu, Y., Zhu, Y., Zhang, Y., and Wang, K., 2019, Synthesizing vitamin E molecularly imprinted polymers via precipitation polymerization, J. Chem. Eng. Data, 64 (3), 1045–1050.

[54] Liu, G., Huang, X., Li, L., Xu, X., Zhang, Y., Lv, J., and Xu, D., 2019, Recent advances and perspectives of molecularly imprinted polymer-based fluorescent sensors in food and environment analysis, Nanomaterials, 9 (7), 1030.

[55] Liu, W., Holdsworth, C., and Ye, L., 2020, Synthesis of molecularly imprinted polymers using a functionalized initiator for chiral‐selective recognition of propranolol, Chirality, 32 (3), 370–377.‏

[56] Hamed, E.M., and Li, S.F., 2022, Molecularly imprinted polymers-based sensors for bisphenol-A: Recent developments and applications in environmental, food and biomedical analysis, Trends Environ. Anal. Chem., 35, e00167.‏‏

[57] Iacob, B.C., Bodoki, A.E., Oprean, L., and Bodoki, E., 2018, “Metal–Ligand Interactions in Molecular Imprinting” in Ligand, Eds. Saravanan, C., and Biswas, B., IntechOpen, Rijeka, 1875–1895.‏

[58] Mukami, H.W., and Batlokwa, B.S., 2018, Application of a custom-synthesized molecularly imprinted polymer for the selective isolation of total glucose and fructose from 100% fruit juice samples prior to instrumental analysis, Mol. Imprinting, 5 (1), 16–24.‏

[59] Malik, M.I., Shaikh, H., Mustafa, G., and Bhanger, M.I., 2019, Recent Applications of Molecularly Imprinted Polymers in Analytical Chemistry, Sep. Purif. Rev., 48 (3), 179–219.

[60] Song, X., Xu, S., Chen, L., Wei, Y., and Xiong, H., 2014, Recent advances in molecularly imprinted polymers in food analysis, J. Appl. Polym. Sci., 131 (16), 40766.

[61] Sobiech, M., Bujak, P., Luliński, P., and Pron, A., 2019, Semiconductor nanocrystal–polymer hybrid nanomaterials and their application in molecular imprinting, Nanoscale, 11 (25), 12030–12074.

[62] Ali, M.F., Mehamod, F.S., and Yusof, N.N.M., 2018, Utilizing fluorescein methacrylate as fluorescent functional monomer on synthesizing fluorescent molecularly imprinted polymer in sensing caffeine, AIP Conf. Proc., 1985 (1), 050005.

[63] Triadhi, U., Zulfikar, M.A., Setiyanto, H., and Amran, M.B., 2018, Effects of (monomer – crosslinker - initiator) composition during non imprinted polymers synthesis for catechin retention, J. Phys.: Conf. Ser., 1013, 012192.

[64] Zhang, P., Ji, X., Zhang, H., and Xia, B., 2017, Quantum investigation into intermolecular interactions between bisphenol A and 2-vinyl/4-vinylpyridine: Theoretical insight into molecular imprinting complexes, Comput. Theor. Chem., 1108, 76–85.

[65] Janczura, M., Sobiech, M., Giebułtowicz, J., and Luliński, P., 2021, Computational and experimental designing of imprinted sorbent for the determination of nitroxidative stress products: An analysis of 4-hydroxyphenylacetic acid conversion, J. Mater. Sci., 56 (14), 8439–8460.

[66] Suryana, S., Mutakin, M., Rosandi, Y., and Hasanah, A.N., 2021, An update on molecularly imprinted polymer design through a computational approach to produce molecular recognition material with enhanced analytical performance, Molecules, 26 (7), 1891.

[67] Cai, T., Zhou, Y., Liu, H., Li, J., Wang, X., Zhao, S., and Gong, B., 2021, Preparation of monodisperse, restricted-access, media-molecularly imprinted polymers using bi-functional monomers for solid-phase extraction of sarafloxacin from complex samples, J. Chromatogr. A, 1642, 462009.

[68] Ndunda, E.N., 2020, Molecularly imprinted polymers—A closer look at the control polymer used in determining the imprinting effect: A mini review, J. Mol. Recognit., 33 (11), e2855.

[69] Liu, Y., Lian, Z., Li, F., Majid, A., and Wang, J., 2021, Review on molecular imprinting technology and its application in pre-treatment and detection of marine organic pollutants, Mar. Pollut. Bull., 169, 112541.

[70] Schauperl, M., and Lewis, D.W., 2015, Probing the structural and binding mechanism heterogeneity of molecularly imprinted polymers, J. Phys. Chem. B, 119 (2), 563–571.

[71] Chen, L., Wang, X., Lu, W., Wu, X., and Li, J., 2016, Molecular imprinting: Perspectives and applications, Chem. Soc. Rev., 45 (8), 2137–2211.‏

[72] Bakar, N.A., Ahmad, M., and Daik, R., 2008, Molecularly imprinted polymer for recognition of p-xylene in organic medium, Sains Malays., 37 (4), 373–376.

[73] Wu, N., Feng, L., Tan, Y., and Hu, J., 2009, An optical reflected device using a molecularly imprinted polymer film sensor, Anal. Chim. Acta, 653 (1), 103–108.

[74] Zarejousheghani, M., Lorenz, W., Vanninen, P., Alizadeh, T., Cämmerer, M., and Borsdorf, H., 2019, Molecularly imprinted polymer materials as selective recognition sorbents for explosives: A review, Polymers, 11 (5), 888.

[75] Huang, J.J., Liu, J., Liu, J.X., and Wang, J.P., 2020, A microtitre chemiluminescence sensor for detection of pyrethroids based on dual‐dummy‐template molecularly imprinted polymer and computational simulation, Luminescence, 35 (1), 120–128.

[76] Altintas, Z., Guerreiro, A., Piletsky, S.A., and Tothill, I.E., 2015, NanoMIP based optical sensor for pharmaceuticals monitoring, Sens. Actuators, B, 213, 305–313.

[77] Zhang, Y., Qian, L., Yin, W., He, B., Liu, F., Hou, C., Huo, D., and Fa, H., 2016, A dual read-out molecularly imprinted composite membrane sensor based on zinc porphyrin for the detection of dimethyl methylphosphonate, Chem. Res. Chin. Univ., 32 (5), 725–730.

[78] Smolinska-Kempisty, K., Ahmad, O.S., Guerreiro, A., Karim, K., Piletska, E., and Piletsky, S., 2017, New potentiometric sensor based on molecularly imprinted nanoparticles for cocaine detection, Biosens. Bioelectron., 96, 49–54.

[79] Biswas, T.K., Yusoff, M.M., Sarjadi, M.S., Arshad, S.E., Musta, B., and Rahman, M.L., 2021, Ion-imprinted polymer for selective separation of cobalt, cadmium and lead ions from aqueous media, Sep. Sci. Technol., 56 (4), 671–680.‏

[80] Bhadra, J., Alkareem, A., and Al-Thani, N., 2020, A review of advances in the preparation and application of polyaniline based thermoset blends and composites, J. Polym. Res., 27 (5), 122.

[81] Zink, S., Moura, F.A., da Silva Autreto, P.A., Galvão, D.S., and Mizaikoff, B., 2018, Efficient prediction of suitable functional monomers for molecular imprinting via local density of states calculations, Phys. Chem. Chem. Phys., 20 (19), 13153–13158.

[82] Zhang, X., Shen, F., Zhang, Z., Xing, Y., and Ren, X., 2014, Synthesis of a novel cross-linker doubles as a functional monomer for preparing a water compatible molecularly imprinted polymer, Anal. Methods, 6 (23), 9483–9489.

[83] Safdar, M., Akhlaq, M., Alam, S., Rashid, S.A., and Hussain, A., 2016, Design and preparation of EGDMA cross-linked polyvinylpyrrolidone/acrylic acid hydrogel for controlled delivery of dexibuprofen, Lat. Am. J. Pharm., 35 (5A), 1182–1191.‏

[84] Golker, K., and Nicholls, I.A., 2016, The effect of crosslinking density on molecularly imprinted polymer morphology and recognition, Eur. Polym. J., 75, 423–430.

[85] Ahmad, A.L., Lah, N.F.C., and Low, S.C., 2018, Configuration of molecular imprinted polymer for electrochemical atrazine detection, J. Polym. Res., 25 (11), 243.‏

[86] Canfarotta, F., Poma, A., Guerreiro, A., and Piletsky, S., 2016, Solid-phase synthesis of molecularly imprinted nanoparticles, Nat. Protoc., 11 (3), 443–455.‏

[87] Wang, Z., Long, R., Peng, M., Li, T., and Shi, S., 2019, Molecularly imprinted polymers-coated CdTe quantum dots for highly sensitive and selective fluorescent determination of ferulic acid, J. Anal. Methods Chem., 2019, 1505878.

[88] Liu, Z., Zhang, Y., Feng, J., Han, Q., and Wei, Q., 2019, Ni(OH)2 nanoarrays based molecularly imprinted polymer electrochemical sensor for sensitive detection of sulfapyridine, Sens. Actuators, B, 287, 551–556.

[89] Cormack, P.A.G., and Elorza, A.Z., 2004, Molecularly imprinted polymers: Synthesis and characterisation, J. Chromatogr. B, 804 (1), 173–182.

[90] Azimi, M., Ahmadi Golsefidi, M., Varasteh Moradi, A., Ebadii, M., and Zafar Mehrabian, R., 2020, A novel method for extraction of galegine by molecularly imprinted polymer (MIP) technique reinforced with graphene oxide and its evaluation using polarography, J. Anal. Methods Chem., 2020, 3646712.‏

[91] Yuan, D., Fu, D., and Wang, C., 2021, Selective removal of Congo red from wastewater using molecularly imprinted polymer, Sep. Sci. Technol., 56 (2), 233–241.‏

[92] Giovannoli, C., Passini, C., Di Nardo, F., Anfossi, L., Baggiani, C., and Nicholls, I.A., 2018, Affinity capillary electrochromatography of molecularly imprinted thin layers grafted onto silica capillaries using a surface-bound azo-initiator and living polymerization, Polymers, 10 (2), 192.‏

[93] Agrofoglio, L.A., Krstulja, A., De Schutter, C., Favetta, P., Delépée, R., Roy, V., Dejous, C., Hallil, H., Lachaud, J.L., Lebal, N., Omar Aouled, N., Raimbault, V., Rebière, D., Dulong, S., Levi, F., Junot, C., Théodoro, F., Pruvost, A., and Vidal, R., 2014, Detection of urinary modified nucleosides by a bulk acoustic wave MIP sensor–Results and future work, IRBM, 35 (2), 66–71.

[94] Kamel, A.H., Ezzat, S., Ahmed, M.A., Amr, A.E.G.E., Almehizia, A.A., and Al-Omar, M.A., 2020, Modified potentiometric screen-printed electrodes based on imprinting character for sodium deoxycholate determination, Biomolecules, 10 (2), 251.‏

[95] Çakır, O., and Baysal, Z., 2019, Pesticide analysis with molecularly imprinted nanofilms using surface plasmon resonance sensor and LC-MS/MS: Comparative study for environmental water samples, Sens. Actuators, B, 297, 126764.

[96] Saylan, Y., Akgönüllü, S., Çimen, D., Derazshamshir, A., Bereli, N., Yılmaz, F., and Denizli, A., 2017, Development of surface plasmon resonance sensors based on molecularly imprinted nanofilms for sensitive and selective detection of pesticides, Sens. Actuators, B, 241, 446–454.

[97] Lim, K.F., and Holdsworth, C.I., 2018, Effect of formulation on the binding efficiency and selectivity of precipitation molecularly imprinted polymers, Molecules, 23 (11), 2996.

[98] Castro-Grijalba, A., Montes-García, V., Cordero-Ferradás, M.J., Coronado, E., Pérez-Juste, J., and Pastoriza-Santos, I., 2020, SERS-based molecularly imprinted plasmonic sensor for highly sensitive PAH detection, ACS Sens., 5 (3), 693–702.

[99] Huang, J., Tong, J., Luo, J., Zhu, Y., Gu, Y., and Liu, X., 2018, Green synthesis of water-compatible fluorescent molecularly imprinted polymeric nanoparticles for efficient detection of paracetamol, ACS Sustainable Chem. Eng., 6 (8), 9760–9770.

[100] Fauziah, S., Gafur, A.M., Soekamto, N., Taba, P., and Sapar, A., 2021, Synthesis and characterization of molecularly imprinted polymers of di-(2-Ethylhexyl) phthalate using the precipitation polymerization method, Egypt. J. Chem., 64 (5), 2385–2392.‏

[101] Winingsih, W., Ibrahim, S., and Damayanti, S., 2022, Purification of andrographolide methanolic extract using molecularly imprinted polymer prepared by precipitation polymerization, Sci. Pharm., 90 (2), 27.‏

[102] Feng, G., Sun, J., Wang, M., Wang, M., Li, Z., Wang, S., Zheng, L., Wang, J., She, Y., and Abd El-Aty, A.M., 2021, Preparation of molecularly imprinted polymer with class-specific recognition for determination of 29 sulfonylurea herbicides in agro-products, J. Chromatogr. A, 1647, 462143.

[103] Amaly, N., Istamboulie, G., El-Moghazy, A.Y., and Noguer, T., 2021, Reusable molecularly imprinted polymeric nanospheres for diclofenac removal from water samples, J. Chem. Res., 45 (1-2), 102–110.

[104] Hasanah, A.N., Soni, D., Pratiwi, R., Rahayu, D., Megantara, S., and Mutakin, M., 2020, Synthesis of diazepam-imprinted polymers with two functional monomers in chloroform using a bulk polymerization method, J. Chem., 2020, 7282415.

[105] Hasanah, A.N., Dwi Utari, T.N., and Pratiwi, R., 2019, Synthesis of atenolol-imprinted polymers with methyl methacrylate as functional monomer in propanol using bulk and precipitation polymerization method, J. Anal. Methods Chem., 2019, 9853620.‏

[106] Hou, L., Han, X., and Wang, N., 2020, High performance of molecularly imprinted polymer for the selective adsorption of erythromycin in water, Colloid Polym. Sci., 298 (8), 1023–1033.‏

[107] Zhang, Y., Huang, Y., Kang, Y., Miao, J., and Lai, K., 2021, Selective recognition and determination of malachite green in fish muscles via surface-enhanced Raman scattering coupled with molecularly imprinted polymers, Food Control, 130, 108367.‏

[108] Zhang, X., Sun, X., Wang, M., Wang, Y., Wu, Q., Ji, L., Li, Q., Yang, J., and Zhou, Q., 2020, Dummy molecularly imprinted microspheres prepared by Pickering emulsion polymerization for matrix solid-phase dispersion extraction of three azole fungicides from fish samples, J. Chromatogr. A, 1620, 461013.‏

[109] Jayasinghe, G.D.T.M., Domínguez-González, R., Bermejo-Barrera, P., and Moreda-Piñeiro, A., 2020, Room temperature phosphorescent determination of aflatoxins in fish feed based on molecularly imprinted polymer-Mn-doped ZnS quantum dots, Anal. Chim. Acta, 1103, 183–191.‏

[110] Öter, Ç., and Zorer, Ö. S., 2021, Molecularly imprinted polymer synthesis and selective solid phase extraction applications for the detection of ziram, a dithiocarbamate fungicide, Chem. Eng. J. Adv., 7, 100118.

[111] Liu, X., Wu, F., Au, C., Tao, Q., Pi, M., and Zhang, W., 2019, Synthesis of molecularly imprinted polymer by suspension polymerization for selective extraction of p‐hydroxybenzoic acid from water, J. Appl. Polym. Sci., 136 (3), 46984.‏

[112] Ahmad, O.S., Bedwell, T.S., Esen, C., Garcia-Cruz, A., and Piletsky, S.A., 2019, Molecularly imprinted polymers in electrochemical and optical sensors, Trends Biotechnol., 37 (3), 294–309.

[113] Yang, S., Wang, Y., Jiang, Y., Li, S., and Liu, W., 2016, Molecularly imprinted polymers for the identification and separation of chiral drugs and biomolecules, Polymers, 8 (6), 216.

[114] Wang, Y., Wang, J., Cheng, R., Sun, L., Dai, X., and Yan, Y., 2018, Synthesis of molecularly imprinted dye‐silica nanocomposites with high selectivity and sensitivity: Fluorescent imprinted sensor for rapid and efficient detection of τ‐fluvalinate in vodka, J. Sep. Sci., 41 (8), 1880–1887.

[115] Ye, T., Yin, W., Zhu, N., Yuan, M., Cao, H., Yu, J., Gou, Z., Wang, X., Zhu, H., Reyihanguli, A., and Xu, F., 2018, Colorimetric detection of pyrethroid metabolite by using surface molecularly imprinted polymer, Sens. Actuators, B, 254, 417–423.

[116] Capoferri, D., Álvarez-Diduk, R., Del Carlo, M., Compagnone, D., and Merkoçi, A., 2018, Electrochromic molecular imprinting sensor for visual and smartphone-based detections, Anal. Chem., 90 (9), 5850–5856.

[117] Feng, S., Hu, Y., Ma, L., and Lu, X., 2017, Development of molecularly imprinted polymers-surface-enhanced Raman spectroscopy/colorimetric dual sensor for determination of chlorpyrifos in apple juice, Sens. Actuators, B, 241, 750–757.

[118] Foguel, M.V., Pedro, N.T.B., Zanoni, M.V.B., Sotomayor, M.P.T., 2017, Molecularly imprinted polymer (MIP): A promising recognition system for development of optical sensor for textile dyes, Procedia Technol., 27, 299–300.

[119] Kadhem, A.J., Xiang, S., Nagel, S., Lin, C.H., and Fidalgo de Cortalezzi, M., 2018, Photonic molecularly imprinted polymer film for the detection of testosterone in aqueous samples, Polymers, 10 (4), 349.

[120] Yang, Q., Wu, X., Peng, H., Fu, L., Song, X., Li, J., Xiong, H., and Chen, L., 2018, Simultaneous phase-inversion and imprinting based sensor for highly sensitive and selective detection of bisphenol A, Talanta, 176, 595–603.

[121] Xiao, D., Su, L., Teng, Y., Hao, J., and Bi, Y., 2020, Fluorescent nanomaterials combined with molecular imprinting polymer: Synthesis, analytical applications, and challenges, Microchim. Acta, 187 (7), 399.

[122] Ghasempour, Z., Khaled-Abad, M.A., Vardast, M.R., Bari, M.R., and Kia, E.M., 2019, Fabrication of betanin imprinted polymer for rapid detection of red beet adulteration in pomegranate juice, Polym. Bull., 76 (4), 1793–1805.

[123] Yang, Q., Li, J., Wang, X., Peng, H., Xiong, H., and Chen, L., 2018, Strategies of molecular imprinting-based fluorescence sensors for chemical and biological analysis, Biosens. Bioelectron., 112, 54–71.

[124] Li, X., Jiao, H.F., Shi, X.Z., Sun, A., Wang, X., Chai, J., Li, D.X., and Chen, J., 2018, Development and application of a novel fluorescent nanosensor based on FeSe quantum dots embedded silica molecularly imprinted polymer for the rapid optosensing of cyfluthrin, Biosens. Bioelectron., 99, 268–273.

[125] Xiao, T.T., Shi, X.Z., Jiao, H.F., Sun, A.L., Ding, H., Zhang, R.R., Pan, D.D., Li, D.X., and Chen, J., 2016, Selective and sensitive determination of cypermethrin in fish via enzyme-linked immunosorbent assay-like method based on molecularly imprinted artificial antibody-quantum dot optosensing materials, Biosens. Bioelectron., 75, 34–40.

[126] Sun, A., Chai, J., Xiao, T., Shi, X., Li, X., Zhao, Q., Li, D., and Chen, J., 2018, Development of a selective fluorescence nanosensor based on molecularly imprinted-quantum dot optosensing materials for saxitoxin detection in shellfish samples, Sens. Actuators, B, 258, 408–414.

[127] Xu, S., Lin, G., Zhao, W., Wu, Q., Luo, J., Wei, W., Liu, X., and Zhu, Y., 2018, Necklace-like molecularly imprinted nanohybrids based on polymeric nanoparticles decorated multiwalled carbon nanotubes for highly sensitive and selective melamine detection, ACS Appl. Mater. Interfaces, 10 (29), 24850–24859.

[128] Marjanovic, M., Schranzhofer, L., Jungmann, C., and Lieberzeit, P.A., 2019, Surface molecular imprinting strategies: an innovative tool to detect engineered nanoparticles in aqueous solutions, ECS Meet. Abstr., MA2019-02, 2282.‏

[129] Xu, Y., Zhang, W., Shi, J., Zou, X., Li, Y., Haroon Elrasheid, T., Huang, X., Li, Z., Zhai, X., and Hu, X., 2017, Electrodeposition of gold nanoparticles and reduced graphene oxide on an electrode for fast and sensitive determination of methylmercury in fish, Food Chem., 237, 423–430.

[130] Rao, H., Chen, M., Ge, H., Lu, Z., Liu, X., Zou, P., Wang, X., He, H., Zeng, X., and Wang, Y., 2017, A novel electrochemical sensor based on Au@PANI composites film modified glassy carbon electrode binding molecular imprinting technique for the determination of melamine, Biosens. Bioelectron., 87, 1029–1035.

[131] Beloglazova, N.V., Lenain, P., De Rycke, E., Goryacheva, I.Y., Knopp, D., and De Saeger, S., 2018, Capacitive sensor for detection of benzo(a)pyrene in water, Talanta, 190, 219–225.

[132] Wang, H., Yao, S., Liu, Y., Wei, S., Su, J., and Hu, G., 2017, Molecularly imprinted electrochemical sensor based on Au nanoparticles in carboxylated multi-walled carbon nanotubes for sensitive determination of olaquindox in food and feedstuffs, Biosens. Bioelectron., 87, 417–421.

[133] González-Vila, Á., Debliquy, M., Lahem, D., Zhang, C., Mégret, P., Caucheteur, C., 2017, Molecularly imprinted electropolymerization on a metal-coated optical fiber for gas sensing applications, Sens. Actuators, B, 244, 1145–1151.

[134] Zhang, R.R., Zhan, J., Xu, J.J., Chai, J.Y., Zhang, Z.M., Sun, A.L., Chen, J., and Shi, X.Z., 2020, Application of a novel electrochemiluminescence sensor based on magnetic glassy carbon electrode modified with molecularly imprinted polymers for sensitive monitoring of bisphenol A in seawater and fish samples, Sens. Actuators, B, 317, 128237.

[135] Serrano, V.M., Cardoso, A.R., Diniz, M., and Sales, M.G.F., 2020, In-situ production of Histamine-imprinted polymeric materials for electrochemical monitoring of fish, Sens. Actuators, B, 311, 127902.

[136] Hubilla, F.A.D., Mabilangan, A.I., Advincula, R.C., and del Mundo, F.R., 2017, A surface plasmon resonance histamine sensor based on an electropolymerized molecularly imprinted polymer (E-MIP), MATEC Web Conf., 95, 02006.

[137] Arabi, M., Ostovan, A., Bagheri, A.R., Guo, X., Wang, L., Li, J., Wang, X., Li, B., and Chen, L., 2020, Strategies of molecular imprinting-based solid-phase extraction prior to chromatographic analysis, TrAC, Trends Anal. Chem., 128, 115923.

[138] Jia, B.J., Huang, J., Liu, J.X., Wang, J.P., 2019, Detection of chloramphenicol in chicken, pork and fish with a molecularly imprinted polymer-based microtiter chemiluminescence method, Food Addit. Contam., Part A, 36 (1), 74–83.

[139] Atlabachew, M., Torto, N., Chandravanshi, B.S., Redi‐Abshiro, M., Chigome, S., Mothibedi, K., and Combrinck, S., 2016, A (−)‐norephedrine‐based molecularly imprinted polymer for the solid‐phase extraction of psychoactive phenylpropylamino alkaloids from Khat (Catha edulis Vahl. Endl.) chewing leaves, Biomed. Chromatogr., 30 (7), 1007–1015.

[140] Anene, A., Hosni, K., Chevalier, Y., Kalfat, R., and Hbaieb, S., 2016, Molecularly imprinted polymer for extraction of patulin in apple juice samples, Food Control, 70, 90–95.

[141] Maragou, N.C., Thomaidis, N.S., Theodoridis, G.A., Lampi, E.N., and Koupparis, M.A., 2020, Determination of bisphenol A in canned food by microwave assisted extraction, molecularly imprinted polymer-solid phase extraction and liquid chromatography-mass spectrometry, J. Chromatogr. B, 1137, 121938.

[142] Wu, B., Muhammad, T., Aihebaier, S., Karim, K., Hu, Y., and Piletsky, S., 2020, A molecularly imprinted polymer based monolith pipette tip for solid-phase extraction of 2,4-dichlorophenoxyacetic acid in an aqueous sample, Anal. Methods, 12 (40), 4913–4921.‏

[143] Khan, S., Bhatia, T., Trivedi, P., Satyanarayana, G.N.V., Mandrah, K., Saxena, P.N., Mudiam, M.K.R., and Roy, S.K., 2016, Selective solid-phase extraction using molecularly imprinted polymer as a sorbent for the analysis of fenarimol in food samples, Food Chem., 199, 870–875.

[144] Zhu, G., Cheng, G., Wang, P., Li, W., Wang, Y., and Fan, J., 2019, Water compatible imprinted polymer prepared in water for selective solid phase extraction and determination of ciprofloxacin in real samples, Talanta, 200, 307–315.

[145] Zhao, M., Shao, H., He, Y., Li, H., Yan, M., Jiang, Z., Wang, J., Abd El-Aty, A.M., Hacımüftüoğlu, A., Yan, F., Wang, Y., and She, Y., 2019, The determination of patulin from food samples using dual-dummy molecularly imprinted solid-phase extraction coupled with LC-MS/MS, J. Chromatogr. B, 1125, 121714.

[146] Lu, W., Wang, X., Wu, X., Liu, D., Li, J., Chen, L., and Zhang, X., 2017, Multi-template imprinted polymers for simultaneous selective solid-phase extraction of six phenolic compounds in water samples followed by determination using capillary electrophoresis, J. Chromatogr. A, 1483, 30–39.

[147] Hashemi-Moghaddam, H., Hosseni, M., and Mohammadhosseini, M., 2017, Preparation of molecularly imprinted polymers on the surface of optical fiber for HS-solid-phase microextraction of phenol, Sep. Sci. Technol., 52 (11), 1826–1834.

[148] Sarafraz-Yazdi, A., and Razavi, N., 2015, Application of molecularly-imprinted polymers in solid-phase microextraction techniques, TrAC, Trends Anal. Chem., 73, 81–90.

[149] Ma, J.K., Huang, X.C., and Wei, S.L., 2018, Preparation and application of chlorpyrifos molecularly imprinted solid‐phase microextraction probes for the residual determination of organophosphorous pesticides in fresh and dry foods, J. Sep. Sci., 41 (15), 3152–3162.

[150] Xiang, X., Wang, Y., Zhang, X., Huang, M., Li, X., and Pan, S., 2020, Multifiber solid‐phase microextraction using different molecularly imprinted coatings for simultaneous selective extraction and sensitive determination of organophosphorus pesticides, J. Sep. Sci., 43 (4), 756–765.

[151] Sun, C., Wang, J., Huang, J., Yao, D., Wang, C.Z., Zhang, L., Hou, S., Chen, L., and Yuan, C.S., 2017, The multi-template molecularly imprinted polymer based on SBA-15 for selective separation and determination of panax notoginseng saponins simultaneously in biological samples, Polymers, 9 (12), 653.

[152] Ashley, J., Shahbazi, M.A., Kant, K., Chidambara, V.A., Wolff, A., Bang, D.D., and Sun, Y., 2017, Molecularly imprinted polymers for sample preparation and biosensing in food analysis: Progress and perspectives, Biosens. Bioelectron., 91, 606–615.

[153] Jayasinghe, G.D.T.M., Domínguez-González, R., Bermejo-Barrera, P., and Moreda-Piñeiro, A., 2020, Ultrasound assisted combined molecularly imprinted polymer for the selective micro-solid phase extraction and determination of aflatoxins in fish feed using liquid chromatography-tandem mass spectrometry, J. Chromatogr. A, 1609, 460431.

[154] Barciela-Alonso, M.C., Plata-García, V., Rouco-López, A., Moreda-Piñeiro, A., and Bermejo-Barrera, P., 2014, Ionic imprinted polymer based solid phase extraction for cadmium and lead pre-concentration/determination in seafood, Microchem. J., 114, 106–110.

[155] Ding, H., Jiao, H.F., Shi, X.Z., Sun, A.L., Guo, X.Q., Li, D.X., and Chen, J., 2017, Molecularly imprinted optosensing sensor for highly selective and sensitive recognition of sulfadiazine in seawater and shrimp samples, Sens. Actuators, B, 246, 510–517.

[156] Moreno-González, D., Jáč, P., Riasová, P., and Nováková, L., 2020, In-line molecularly imprinted polymer solid phase extraction-capillary electrophoresis coupled with tandem mass spectrometry for the determination of patulin in apple-based food, Food Chem., 334, 127607.

[157] Zhou, Q., Tan, X.C., Guo, X.J., Huang, Y.J., and Zhai, H.Y., 2018, Preparation and characterization of molecularly imprinted solid-phase extraction column coupled with high-performance liquid chromatography for selective determination of melamine, R. Soc. Open Sci., 5 (9), 180750.

[158] Bai, X., Zhang, B., Liu, M., Hu, X., Fang, G., and Wang, S., 2020, Molecularly imprinted electrochemical sensor based on polypyrrole/dopamine@graphene incorporated with surface molecularly imprinted polymers thin film for recognition of olaquindox, Bioelectrochemistry, 132, 107398.

[159] Zheng, X., and Wang, J., 2019, A novel metal-organic framework composite, MIL-101(Cr)@MIP, as an efficient sorbent in solid-phase extraction coupling with HPLC for tribenuron-methyl determination, Int. J. Anal. Chem., 2019, 2547280.

[160] Bitas, D., and Samanidou, V., 2018, Molecularly imprinted polymers as extracting media for the chromatographic determination of antibiotics in milk, Molecules, 23 (2), 316.

[161] Zhai, H., Liang, G., Guo, X., Chen, Z., Yu, J., Lin, H., and Zhou, Q., 2019, Novel coordination imprinted polymer monolithic column applied to the solid-phase extraction of flumequine from fish samples, J. Chromatogr. B, 1118, 55–62.

[162] Huang, L., Zhai, H., Liang, G., Su, Z., Yuan, K., Lu, G., and Pan, Y., 2016, Chip-based dual-molecularly imprinted monolithic capillary array columns coated Ag/GO for selective extraction and simultaneous determination of bisphenol A and nonyl phenol in fish samples, J. Chromatogr. A, 1474, 14–22.

[163] Tang, T., Wei, F., Wang, X., Ma, Y., Song, Y., Ma, Y., Song, Q., Xu, G., Cen, Y., and Hu, Q., 2018, Determination of semicarbazide in fish by molecularly imprinted stir bar sorptive extraction coupled with high performance liquid chromatography, J. Chromatogr. B, 1076, 8–14.

[164] Guo, Y., Yuan, G., Hu, X., Zhang, J., and Fang, G., 2022, A high-luminescence biomimetic nanosensor based on N, S-GQDs-embedded zinc-based metal–organic framework@molecularly imprinted polymer for sensitive detection of octopamine in fermented foods, Foods, 11 (9), 1348.‏

[165] Hong, L., Pan, M., Yang, X., Xie, X., Liu, K., Yang, J., Wang, S., and Wang, S., 2022, A UCMPs@MIL-100 based thermo-sensitive molecularly imprinted fluorescence sensor for effective detection of β-lactoglobulin allergen in milk products, J. Nanobiotechnol., 20 (1), 51.‏‏

[166] Peng, S., Wang, A., Lian, Y., Jia, J., Ji, X., Yang, H., Li, J., Yang, S., Liao, J., and Zhou, S., 2022, Technology for rapid detection of cyromazine residues in fruits and vegetables: Molecularly imprinted electrochemical sensors, Biosensors, 12 (6), 414.‏

[167] Chuiprasert, J., Boontanon, S.K., Srinives, S., Boontanon, N., Polprasert, C., and Ramungul, N., 2022, Molecularly imprinted polymer functionalized on reduced graphene oxide electrochemical sensor for detection of ciprofloxacin, IOP Conf. Ser.: Earth Environ. Sci., 973, 012003.‏

[168] Herrera-Chacon, A., Gonzalez-Calabuig, A., and del Valle, M., 2021, Dummy molecularly imprinted polymers using DNP as a template molecule for explosive sensing and nitroaromatic compound discrimination, Chemosensors, 9 (9), 255.‏

[169] Thach, U.D., Nguyen Thi, H.H., Pham, T.D., Mai, H.D., and Nhu-Trang, T.T., 2021, Synergetic effect of dual functional monomers in molecularly imprinted polymer preparation for selective solid phase extraction of ciprofloxacin, Polymers, 13 (16), 2788.‏

[170] Chen, J., Tan, L., Cui, Z., Qu, K., and Wang, J., 2022, Graphene oxide molecularly imprinted polymers as novel adsorbents for solid-phase microextraction for selective determination of norfloxacin in the marine environment, Polymers, 14 (9), 1839.‏

[171] Tamandani, M., Hashemi, S.H., Kaykhaii, M., Jamali Keikha, A., and Nasiriyan, A., 2022, Determination of profenofos in seawater and foodstuff samples after its molecularly imprinted polymer pipette-tip micro solid phase extraction optimized by response surface methodology, BMC Chem., 16 (1), 12.‏

[172] Hroboňová, K., and Lomenova, A., 2018, Molecularly imprinted polymer as stationary phase for HPLC separation of phenylalanine enantiomers, Monatsh. Chem., 149 (5), 939–946.‏

[173] Pan, Y., Liu, X., Liu, J., Wang, J., Liu, J., Gao, Y., and Ma, N., 2022, Chemiluminescence sensors based on molecularly imprinted polymers for the determination of organophosphorus in milk, J. Dairy Sci., 105 (4), 3019–3031.‏

[174] Abdulhussein, A.Q., Jamil, A.K.M., and Bakar, N.K.A., 2021, Magnetic molecularly imprinted polymer nanoparticles for the extraction and clean-up of thiamethoxam and thiacloprid in light and dark honey, Food Chem., 359, 129936.‏

[175] Ansari, S., 2017, Combination of molecularly imprinted polymers and carbon nanomaterials as a versatile biosensing tool in sample analysis: recent applications and challenges, TrAC, Trends Anal. Chem., 93, 134–151.

[176] Rangel, P.X.M., Laclef, S., Xu, J., Panagiotopoulou, M., Kovensky, J., Bui, B.T.S., and Haupt, K., 2019, Solid-phase synthesis of molecularly imprinted polymer nanolabels: Affinity tools for cellular bioimaging of glycans, Sci. Rep., 9 (1), 3923.

[177] Florea, A., Feier, B., and Cristea, C., 2019, “In Situ Analysis Based on Molecularly Imprinted Polymer Electrochemical Sensors” in Comprehensive Analytical Chemistry, Elsevier, Amsterdam, 193–234.

[178] Cao, Y., Feng, T., Xu, J., and Xue, C., 2019, Recent advances of molecularly imprinted polymer-based sensors in the detection of food safety hazard factors, Biosens. Bioelectron., 141, 111447.

[179] Garcia, R., da Silva, M.D.G., and Cabrita, M.J., 2018, “On-off” switchable tool for food sample preparation: merging molecularly imprinting technology with stimuli-responsive blocks. Current status, challenges and highlighted applications, Talanta, 176, 479–484.

[180] Sarpong, K.A., Xu, W., Huang, W., and Yang, W., 2019, The development of molecularly imprinted polymers in the clean-up of water pollutants: A review, Am. J. Anal. Chem., 10 (5), 202–226.


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