Synthesis and Characterization of Ferrofluid-Chitosan-Au Nanoparticles as Brachytherapy Agent Candidate
Muflikhah Muflikhah(1*), Ahmad Marzuki Ramadhan(2), Maria Christina Prihatiningsih(3), Mujamilah Mujamilah(4), Aloma Karo Karo(5)
(1) Center for Science and Technology of Advanced Materials, National Nuclear Energy Agency of Indonesia, Kawasan Puspiptek Serpong, Banten 15314, Indonesia
(2) Polytechnic Institute of Nuclear Technology, National Nuclear Energy Agency of Indonesia, Jl. Babarsari POB 6101 Yk bb, Yogyakarta 55281, Indonesia
(3) Polytechnic Institute of Nuclear Technology, National Nuclear Energy Agency of Indonesia, Jl. Babarsari POB 6101 Yk bb, Yogyakarta 55281, Indonesia
(4) Center for Science and Technology of Advanced Materials, National Nuclear Energy Agency of Indonesia, Kawasan Puspiptek Serpong, Banten 15314, Indonesia
(5) Center for Science and Technology of Advanced Materials, National Nuclear Energy Agency of Indonesia, Kawasan Puspiptek Serpong, Banten 15314, Indonesia
(*) Corresponding Author
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[1] Pati, S.S., Singh L.H., Oliveira, A.C., and Garg, V.K., 2016, Chitosan functionalized Fe3O4@Au core-shell nanomaterials for targeted drug delivery, Int. J. Chem. Mol. Nucl. Mater. Metall. Eng., 9 (6), 643–646.
[2] Pati, S.S., Singh, L.H., Guimar, E.M., Mantilla, J., Coaquira, J.A.H., Oliveira, A.C., Sharma, V.K., and Garg, V.K., 2016, Magnetic chitosan-functionalized Fe3O4@Au nanoparticles: Synthesis and characterization, J. Alloys Compd., 684, 68–74.
[3] Sun, S.N., Wei, C., Zhu, Z.Z., Hou, Y.L., Venkatraman, S.S., and Xu, Z.C., 2014, Magnetic iron oxide nanoparticles: Synthesis and surface coating techniques for biomedical applications, Chin. Phys. B, 23 (3), 037503.
[4] Leamy, P.J., 2003, Preparation, characterization, and in vitro testing of poly(lactide-co-glycolide) and dextran magnetic microspheres for in vivo applications, Dissertation, University of Florida.
[5] Mohammed, L., 2016, Polymeric superparamagnetic nanoparticles for drug delivery applications, Thesis, University of Western Ontario.
[6] Sulungbudi, G.T., and Mujamilah, 2016, An effort on homogenizing size distribution of magnetic nanosphere Fe3O4-poly-lactic acid for hyperthermia treatment, MPI, 19 (1), 68–83.
[7] Ebrahimi, M., 2016, A short review on ferrofluids surface modification by natural and biocompatible polymers, Nanomed. J., 3 (3), 155–158.
[8] Wu, W., He, Q., and Jiang, C., 2008, Magnetic iron oxide nanoparticles: Synthesis and surface functionalization strategies, Nanoscale Res. Lett., 3 (11), 397.
[9] Mahdavi, M., Ahmad, M.B., Haron, J., Namvar, F., Nadi, B., Rahman, M.Z., and Amin, J., 2013, Synthesis, surface modification and characterisation of biocompatible magnetic iron oxide nanoparticles for biomedical applications, Molecules, 18 (7), 7533–7548.
[10] Pylypchuk, I.V., Kołodyńska, D., Kozioł, M., and Gorbyk, P.P., 2016, Gd-DTPA adsorption on chitosan/magnetite nanocomposites, Nanoscale Res. Lett., 11 (1), 168.
[11] Qu, H., Ma, H., Riviere, A., Zhou, W., and Connor, C.J.O., 2012, One-pot synthesis in polyamines for preparation of water-soluble magnetite nanoparticles with amine surface reactivity, J. Mater. Chem., 22 (8), 3311–3313.
[12] Abouelmagd, S.A., Ku, Y.J., and Yeo, Y., 2015, Low molecular weight chitosan-coated polymeric nanoparticles for sustained and ph-sensitive delivery of paclitaxel, J. Drug Targeting, 23 (7-8), 725–735.
[13] Muflikhah, Rusdiarso, B., Putra, E.G.R., and Nuryono, 2017, Modification of silica coated on iron sand magnetic material with chitosan for adsorption of Au(III), Indones. J. Chem., 17 (2), 264–273.
[14] Yao, C., Zhang, L., Wang, J., He, Y., Xin, J., Wang, S., Xu, H., and Zhang, Z., 2016, Gold nanoparticle mediated phototherapy for cancer, J. Nanomater., 2016, 5497136.
[15] Boyles, M.S.P., Kristl, T., Andosch, A., Zimmermann, M., Tran, N., Casals, E., Himly, M., Puntes, V., Huber, C.G., Lütz‑Meindl, U., and Duschl, A., 2015, Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components, J. Nanobiotechnology, 13 (1), 84.
[16] Chanda, N., Kan, P., Watkinson, L.D., Shukla, R., Zambre, A., Carmack, T.L., Engelbrecht, H., Lever, J.R., Katti, K., Fent, G.M., Casteel, S.W., Smith, C.J., Miller, W.H., Jurisson, S., Boote, E., Robertson, J.D., Cutler, C., Dobrovolskaia, M., Kannan, R., and Katti, K.V., 2010, Radioactive gold nanoparticles in cancer therapy: Therapeutic efficacy studies of Ga-198 AuNP nanoconstruct in prostate tumor–bearing mice, Nanomed. Nanotechnol. Biol. Med., 6 (2), 201–209.
[17] Ritawidya, R., Pujiyanto, A., Setiawan, H., Ramli, M., and Kurniasih, D., 2012, Synthesis and characterization of poly(amidoamine) dendrimers encapsulated 198Au nanoparticles, At. Indones., 38 (3), 118–126.
[18] Hemalatha, T., Prabu, P., Gunadharini, D.N., and Gowthaman, M.K., 2018, Fabrication and characterization of dual acting oleyl chitosan functionalised iron oxide/gold hybrid nanoparticles for MRI and CT imaging, Int. J. Biol. Macromol., 112, 250–257.
[19] Nasution, T.I., Asrosa, R., Nainggolan, I., Balyan, M., Indah, R., and Wahyudi, A., 2018, Sodium tripolyphosphate cross-linked chitosan based sensor for enhancing sensing properties towards acetone, IOP Conf. Ser.: Mater. Sci. Eng., 309, 012083.
[20] Unsoy, G., Yalcin, S., Khodadust, R., Gunduz, G., and Gunduz, U., 2012, Synthesis optimization and characterization of chitosan-coated iron oxide nanoparticles produced for biomedical applications, J. Nanopart. Res., 14 (11), 964.
[21] Parisien-La Salle, J.C., 2012, In-situ adsorption of gold(III) chloride on activated carbon under pressure oxidation-leaching conditions, Thesis, Mc Gill University.
[22] Zhao, M., Zhao, J., Huang, Z., Wang, S., and Zhang, L., 2019, One pot preparation of magnetic chitosan-cystamine composites for selective recovery of Au (III) from the aqueous solution, Int. J. Biol. Macromol., 137, 721–731.
[23] Liu, X.L., Yang, X., Xin, H.Y., Tang, X.P., Weng, L.J., Han, Y.Y., and Geng, D., 2016, Ecofriendly fabrication of Au/Fe3O4-chitosan composites for catalytic reduction of methyl orange, Dig. J. Nanomater. Biostruct., 11 (2), 337–348.
[24] Pham, X.N., Nguyen, T.P., Pham, T.N., Tran, T.T.N., Tran, T.V.T., 2016, Synthesis and characterization of chitosan- coated magnetite nanoparticles and their application in curcumin drug delivery, Adv. Nat. Sci.: Nanosci. Nanotechnol., 7 (4), 045010.
[25] Shirazi, H., Daneshpour, M., Kashanian, S., and Omidfar, K., 2015, Synthesis, characterization and in vitro biocompatibility study of Au/TMC/Fe3O4 nanocomposites as a promising, nontoxic system for biomedical applications, Beilstein J. Nanotechnol., 6, 1677–1689.
[26] Pestov, A., Nazirov, A., Modin, E., Mironenko, A., and Bratskaya, S., 2014, Mechanism of Au(III) reduction by chitosan: Comprehensive study with 13C and 1H NMR analysis of chitosan degradation products, Carbohydr. Polym., 117, 70–77.
[27] Podrepšek, G.H., Knez, Ž., and Leitgeb, M., 2020, Development of chitosan functionalized magnetic nanoparticles with bioactive compounds, Nanomaterials, 10 (10), 1913.
DOI: https://doi.org/10.22146/ijc.62191
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