Deposition of Hydroxyapatite on Silica Made from Rice Husk Ash to Produce the Powder Component of Calcium Phosphate Cement

Tri Windarti; Widjijono Widjijono; Nuryono Nuryono

doi:10.22146/ijc.57900

Deposition of Hydroxyapatite on Silica Made from Rice Husk Ash to Produce the Powder Component of Calcium Phosphate Cement

https://doi.org/10.22146/ijc.57900

Tri Windarti^(1*), Widjijono Widjijono⁽²⁾, Nuryono Nuryono⁽³⁾

(1) Department of Chemistry, Faculty of Science and Mathematics, Universitas Diponegoro, Jl. Prof. Soedharto SH, Tembalang, Semarang 50275, Indonesia
(2) Department of Dental Biomaterials, Faculty of Dentistry, Universitas Gadjah Mada, Jl. Denta 1, Sekip Utara, Yogyakarta 55281, Indonesia
(3) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara, Yogyakarta 55281, Indonesia
(*) Corresponding Author

Abstract

Hydroxyapatite (HA) has been deposited on silica (SiO₂) particles to produce HA-SiO₂ composite that will be used as the powder component of calcium phosphate cement. HA was expected to be on the composite surface to maintain its bioactivity. SiO₂ was made by the sol-gel method, in which silicate solution was extracted from rice husk ash with NaOH solution. Deposition of HA on SiO₂ was carried out by wet chemical deposition method at various Ca/Si molar ratio (in a range of 5–25) followed by calcination at 600 °C for 2 h. Results showed that HA was successfully deposited on SiO₂ particles. The cell parameters of the HA crystals were slightly distorted by the presence of SiO₂ and HA in the composite had a bigger cell volume than pure HA. The crystallite size of HA in the composites increased with the increase of the Ca/Si ratio but the values were smaller than pure HA. SiO₂ acted as a morphology directing agent. At low Ca/Si ratio, the HA-SiO₂ particles were in a form of short rod-like particles with sizes of < 50 nm, while at high Ca/Si ratio, a mixture of short and long rod-like particles with the size of < 100 nm was obtained. The zeta potential of composites was almost similar to pure HA. These properties indicated that HA-SiO₂ composites support the bioactivity of injectable calcium phosphate cement.

Keywords

hydroxyapatite; silica; rice husk ash; calcium phosphate cement

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DOI: https://doi.org/10.22146/ijc.57900