The Oriented Attachment Model Applied on Crystal Growth of Hydrothermal Derived Magnetite Nanoparticles

https://doi.org/10.22146/ijc.42917

Ahmad Fadli(1*), Amun Amri(2), Iwantono Iwantono(3), Arisman Adnan(4), Sunarno Sunarno(5), Sukoco Sukoco(6), Mayangsari Mayangsari(7)

(1) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km.12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(2) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km.12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(3) Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km.12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(4) Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km.12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(5) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km.12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(6) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km.12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(7) Department of Chemical Engineering, Faculty of Engineering, Universitas Riau, Kampus Binawidya, Jl. HR. Soebrantas Km.12.5, Simpang Baru, Panam Pekanbaru, Riau 28293, Indonesia
(*) Corresponding Author

Abstract


Magnetite (Fe3O4) nanoparticles are very promising to be applied as a drug delivery system (DDS) for cancer chemotherapy. In this research, the crystal growth of hydrothermal derived magnetite particles was studied by oriented attachment (OA) model. The OA model was used to investigate the mechanism and the statistical kinetic of crystal growth. The crystal diameter change as a function of time with different concentration was measured using XRD. Firstly, 0.3248 g FeCl3 and 1.1764 g of sodium citrate, as well as 0.3604 g urea were dissolved into 40 mL of distilled water in a reactor. Subsequently, the reactor temperature was maintained at 210 °C and reaction time of 3.5–12 h in an air oven. The morphology of obtained particles was characterized using TEM, whereas VSM was used to determine the magnetic hysteresis curve. The XRD pattern showed that magnetite was obtained at temperature 210 °C and 3.5 h reaction time, as well as its intensity increased with reaction time. The crystal size of Fe3O4 was 9.44 nm at 3.5 h and appropriate with the oriented attachment model. The magnetite nanoparticles with shaped core-shell size less than 50 nm and suitable for biomedical application especially as drug delivery.


Keywords


magnetite, oriented attachment; crystal growth; hydrothermal, nanoparticles

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References

[1] Hung, L.H., and Lee, A.P., 2007, Microfluidic devices for the synthesis of nanoparticles and biomaterials, J. Med. Biol. Eng., 27(1), 1–6.

[2] Arruebo, M., Fernández-Pacheco, R., Ibarra, M.R., and Santamaría, J., 2007, Magnetics nanoparticles for drug delivery, Nano Today, 2 (3), 22–32.

[3] Chomoucka, J., Drbohlavova, J., Huska, D., Adam, V., Kizek, R., and Hubalek, J., 2010, Magnetic nanoparticles and targeted drug delivering, Pharmacol. Res., 62 (2), 144–149.

[4] Cheng, W., Tang, K., Qi, Y., Sheng, J., and Liu, Z., 2010, One-step synthesis of superparamagnetic monodisperse porous Fe3O4 hollow, J. Mater. Chem., 20 (9), 1799–1805.

[5] Zhang, J., Huang, F., and Lin, Z., 2010, Progress of nanocrystalline growth kinetics based on oriented attachment, Nanoscale, 2 (1), 18–34.

[6] Huang, F., Zhang, H., and Banfield, F.J., 2003, Two-stage crystal-growth kinetics observed during hydrothermal coarsening of nanocrystalline ZnS, Nano Lett., 3 (3), 373–378.

[7] Bae, Y.H., and Park, K., 2011, Targeted drug delivery to tumors, myths, reality and possibility, J. Phys. D: Appl. Phys., 153 (3), 198–205.

[8] Tartaj, P., Morales, M.P., Veintemillas-Verdaguer, S., González-Carreño, T., and Serna, C.J., 2003, The preparation of magnetic nanoparticles for applications in biomedicine, J. Phys. D: Appl. Phys., 36 (13), 182–197.

[9] Mohapatra, M., and Anand, S., 2010, Synthesis and applications of nano-structured iron oxides/hydroxides – A review, J. Eng. Sci. Technol., 2 (8), 127–146.

[10] Cao, X., Zhang, B., Zhao, F., and Feng L., 2012, Synthesis and properties of MPEG-Coated superparamagnetic magnetite nanoparticles, J. Nanomater., 2012, 607296.

[11] Zhang, H., and Banfield, J.F., 1999, New kinetic model for the nanocrystalline anatase-to-rutile transformation revealing rate dependence on number of particles, Am. Mineral., 84 (4), 528–535.

[12] Hwang, N.M., Jung, J.S., and Lee, D.K., 2012, “Thermodynamics and kinetics in the synthesis of monodisperse nanoparticles” in Thermodynamics-Fundamentals and Its Application in Science, Eds., Morales-Rodriguez, M., InTech, 371–388.

[13] Hyeon, T., Lee, S., Park, J., Chung, Y., and Na, H.B., 2001, Synthesis of highly crystalline and monodisperse maghemite nanocrystallites without a size-selection process, J. Am. Chem. Soc., 123 (51), 12798–12801.

[14] Lu, A., Salabas, E.L., and Schuth, F., 2007, Magnetic nanoparticles: Synthesis, protection, functionalization, and application, Angew. Chem. Int. Ed., 46 (8), 222–244.

[15] Chen, B.A., Mao, P., Cheng, J., Gao, F., Xia, G.H., Xu, W.L., Shen, H.L., Ding, J.H., Gao, C., Sun, Q., Chen, W.J., Chen, N.N., Liu, L.J., Li, X.M., and Wang, X.M., 2010, Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and MDR1 shRNA expression vector in leukemia cells, Int. J. Nanomed., 5, 437–444.

[16] Gustafson, H.H., Holt-Casper, D., Grainger, D.W., and Ghandehari, H., 2015, Nanoparticle uptake: The phagocyte problem, Nano Today, 10 (4), 487–510.

[17] Sabyrov, K., Burrows, N.D., and Penn, R.L., 2013, Size-dependent anatase to rutile phase transformation and particle growth, Chem. Mater., 25 (8), 1408–1415.

[18] Coulter, J.A., Jain, S., Butterworth, K.T., Taggart, L.E., Dickson, G.R., McMahon, S.J., Hyland, W.B., Muir, M.F., Trainor, C., Hounsell, A.R., O'Sullivan, J.M., Schettino, G., Currell, F.J., Hirst, D.G., and Prise, K.M., 2012, Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles, Int. J. Nanomed., 7, 2673–2685.



DOI: https://doi.org/10.22146/ijc.42917

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