A Green Synthesis of a Novel Calix[4]Resorcinarene from 7-Hydroxycitronellal Using Microwave Irradiation


Ratnaningsih Eko Sardjono(1*), Iqbal Musthapa(2), Iis Rosliana(3), Fitri Khoerunnisa(4), Galuh Yuliani(5)

(1) Department of Chemistry, Universitas Pendidikan Indonesia
(2) Department of Chemistry, Universitas Pendidikan Indonesia
(3) Department of Chemistry, Universitas Pendidikan Indonesia
(4) Department of Chemistry, Universitas Pendidikan Indonesia
(5) Department of Chemistry, Universitas Pendidikan Indonesia
(*) Corresponding Author


A new versatile macromolecule cyclic C-3,7-dimethyl-7-hydroxycalix[4]resorcinarene (CDHHK4R) has been synthesized from a fragrance agent, 7-hydroxycitronellal, via microwave irradiation. The reaction utilized a domestic microwave oven at various irradiation time and power to yield an optimum condition. As a comparison, the conventional heating method was also employed for the synthesis of the same calix[4]resorcinarene. Compared to the conventional method, microwave-assisted reaction effectively reduced the reaction time, the amount of energy consumption and the waste production. It is found that the synthesis of CDHHK4R by microwave irradiation yielded 77.55% of product, higher than by conventional heating which was only 62.17%.


calix[4]resorcinarene; 7-hydroxycitronellal; microwave irradiation

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DOI: https://doi.org/10.22146/ijc.25466

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