ISOLATION AND IDENTIFICATION OF MAIN AND SIDE PRODUCTS FROM ADDITION REACTION OF CARYOPHYLLENE OXIDE BY FORMIC ACID

https://doi.org/10.22146/ijc.21910

M Muchalal(1*), Trisulistyaningsih Rahayu(2)

(1) Chemistry Department, Faculty of Mathematics and Natural Sciences Gadjah Mada University, Yogyakarta
(2) Chemistry Department, Faculty of Mathematics and Natural Sciences Gadjah Mada University, Yogyakarta
(*) Corresponding Author

Abstract


Main and side products from reaction of caryophyllene oxide and formic acid have been isolated using column chromatography with silica gel 60 G as stationary phase and n-hexane : ethyl acetat (9:1, v/v) as mobile phase. The first and second fraction were analyzed using infrared spectrophotometer, gas chromatography, and gas chromatography-mass spectrometer. Caryophyllene formiate as a main product was found in the first fraction. The side product that had been identified were 4,10,10-trimethyl-7-methylenebicyclo[6,2,0]decane-4-carbaldehyde, 2-(9-hydroxy-4,4,8 trimethyltricyclo[6,3,1,01,5]dodecyl)metanoate, clovanediol,4,11,11-trimethyl-8 methylene-3-bicyclo-[7,2,0]-undecen-5-ol,2,5-(6,10,10 imethyltricyclo[7,2,1,01,9]dodecyl)metanedioat, and derivative of caryophylleneformiate.


Keywords


Isolation; identification; caryophyllene oxide

Full Text:

Full Text PDF


References

[1] Guenther, E., 1950, The Essential Oils, diterjemahkan oleh S. Ketaren, 1990, Minyak Atsiri, jilid IV A, UI Press, Jakarta.

[2] Yang, X., C. Lederer, M. McDaniel, and M. Deinzer, 1993, J. Agric. Food. Chem, 41, 2082-2085.

[3] Wibowo, F.R., 2000, Hidrasi dan Adisi Metanol pada β-Kariofilena, Tesis, Program Pasca Sarjana UGM, Yogyakarta.

[4] Yang, X., and M. Deinzer, 1994, J. Nat. Prod. 57, 4, 514-517.

[5] Arata, K., K. Hayano and H. Shirahama, 1993, Bull. Chem. Soc. Japan, 66,218-223.



DOI: https://doi.org/10.22146/ijc.21910

Article Metrics

Abstract views : 1481 | views : 1879


Copyright (c) 2010 Indonesian Journal of Chemistry

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

 

Indonesian Journal of Chemistry (ISSN 1411-9420 /e-ISSN 2460-1578) - Chemistry Department, Universitas Gadjah Mada, Indonesia.

Web Analytics View The Statistics of Indones. J. Chem.