STUDY OF REACTION OF TRANS-[Pt(15NH3)2(H2O)2]2+ WITH N-ACETYL-L-CYSTEINE

https://doi.org/10.22146/ijc.21839

Sutopo Hadi(1*), Trevor G Appleton(2)

(1) Department of Chemistry, University of Lampung Jl. S. Brojonegoro No. 1 Bandar Lampung 35145
(2) Centre for Metals in Biology, Department of Chemistry, University of Queensland Brisbane QLD 4072
(*) Corresponding Author

Abstract


A study of the reaction between trans-[Pt(15NH3)2(H2O)2](NO3)2 and N-acetyl-L-cysteine (H3accys) was undertaken to confirm the identity of the products formed. In alkaline solution, the platinum products observed were mononuclear species, while in acidic solution, the oligomeric products were obtained. The mass spectrometry of the reaction in alkaline solution showed a sulfur-bridged dinuclear platinum(II) species, trans-[{Pt(H2accys-S)2(15NH3)2}2((-H2accys-S)]+ giving m/z 948 and the lost of two ammines was observed.


Keywords


thiolate; oligomers; 2D NMR; mass spectrometry

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DOI: https://doi.org/10.22146/ijc.21839

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