M. Amzad Hossain(1*), Atiqur Rahman(2), Sun Chul Kang(3)

(1) Chemistry Division, Atomic Energy Centre, GPO Box 164, Ramna, Dhaka-1000
(2) Department of Biotechnology, College of Engineering, Daegu University, Kyungsan 712-714; Department of Applied Chemistry & Chemical Technology, Islamic University, Kushtia-7003
(3) Department of Biotechnology, College of Engineering, Daegu University, Kyungsan 712-714
(*) Corresponding Author


Phytochemical investigations on the chloroform extract of the arial part of Orthosiphon stamineus resulted in isolation of one new prenylated compound 5,7-dimethoxy-3,4′-dihydroxy-3′,8-di-C-prenylflavanone together with four known flavonoids compounds, sinensetin, eupatorin, 5,6,7,4¢-tetramethoxyflavone and 3-hydroxy-5,6,7,4¢-tetramethoxyflavone. The structures were deduced on basis of different analytical methods such as UV, IR, 1H-NMR, 13C-NMR, DEPT, COSY, HMBQ and GC-MS. The prenylated compound is reported for the first time from this plant.


Orthosiphon stamineus; prenylated flavanone; flavonoids

Full Text:

Full Text Pdf


[1] World Health Organisation, 2001, Geneva Legal Status of Traditional Medicine and Complementary/Alternative Medicine, A worldwide Review, 129.

[2] Eisai, P. T., 1995, Indonesia Medicinal Herb Index in Indonesia, 263.

[3] Fomum, Z. T., Ayafor, J. F., and Mbi, C. M., 1986, J Chem Soc, 33, 33-37.

[4] Shibuya, H., Bohgaki, T., Matsubara, T., Watari, M., Ohashi, K., and Kitagawa, I., 1999, Chem. Pharm. Bull, 47, 695-699.

[5] Bwin, D. M., and Gwan, U. S., 1967, Plants with Reputed Hypoglycemic Action, 126-133.

[6] Stampoulis, P., Banskota, A. H., Awale, S., Tran, K. Q., Saik, I. and Kadota, S., 1999, Tetrahedron Letters, 40, 4239-4243.

[7] Hossain, M. A., and Ismail, Z., 2003, Bang J Acad Scis, 23, 174-179.

[8] Tezuka, Y., Stampoulis, P., Banskota, A. H., Awale, S., Tran, K. Q., Saik, I., and Kadota, S., 2000, Chem. Pharm. Bull, 48, 1711-1719.

[9] Sumaryono, W., Proksch, P., Wray, V., Witte, L., and Hartmann, T., 1991, Planta Med. 57, 176-183.

DOI: https://doi.org/10.22146/ijc.21661

Article Metrics

Abstract views : 1492 | views : 1673

Copyright (c) 2010 Indonesian Journal of Chemistry

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.


Indonesian Journal of Chemistry (ISSN 1411-9420 /e-ISSN 2460-1578) - Chemistry Department, Universitas Gadjah Mada, Indonesia.

Analytics View The Statistics of Indones. J. Chem.