Nurdin Saidi(1*), A. Hamid A. Hadi(2), Khalijah Awang(3), Mat Ropi Mukhtar(4)

(1) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Banda Aceh, 23111
(2) Department of Chemistry, Faculty of Science, University of Malaya K. Lumpur
(3) Department of Chemistry, Faculty of Science, University of Malaya K. Lumpur
(4) Department of Chemistry, Faculty of Science, University of Malaya K. Lumpur
(*) Corresponding Author


Isolation, identification and characterization of the compounds isolated from the bark of Cryptocarya ferrea yielded three known aphorpine alkaloids. They are (-)-O-methylisopiline 1, (+)-norlirioferine 2 and (+)-lirioferine 3. Structural elucidation was established through several spectroscopic methods, such as 1D-NMR (1H, 13C, DEPT, NOE), 2D-NMR (COSY, NOESY, HMQC, HMBC), UV, IR, and MS and comparison with the published data.


Cryptocarya ferrea; (-)-o-methylisopiline; (+)-norlirioferine; (+)-lirioferine

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[1] Lee, S.S., Lin, Y.J., Chen, C.K., Liu, K.S., and Chen, C.H., 1993, J. Nat. Prod., 56, 11, 1971-1976.

[2] Lee, S.S., Chen, C.H., and Liu, Y.C., 1993, J. Nat. Prod., 56, 2, 227-232.

[3] Lin, F.W., Wu, P.L., and Wu, T.S., 2001, Chem. Pharm. Bull., 49, 10, 1292-1294.

[4] Bick, I.R.C., Sevenet, T., Sinchai, W., Skelton, B.W., and White, A.H., 1981, Aust. J. Chem., 34, 195-200.

[5] Lamberton, J.A., and Vashist, V.N., 1972, Aust. J. Chem., 25, 2737-2738.

[6] Borthakur, N., Mahanta, P.K., and Rastogi, R.C., 1981, Phytochem., 20, 501-504.

[7] Ohashi, M., Wilson, J.M., Budzikiewicz, H., Shamma, M., Slusarchyk, W.A., and Djerassi, C., 1963, Am. Chem. Soc., 85, 2807-2809.

[8] Chen, C.L., and Chang, H., 1978, Phytochem., 17, 779-782.

[9] Connolly, J.D., Haque, M.E., and Kadir, A.A., 1996, Phytochem., 43, 1, 779-782.

[10] Chen, C.H., Chang, H.M., Cowling, E.B., Hsu, C.Y.H., and Gates, R.P., 1976, Phytochem., 15, 1161-1167.

[11] Castro, O.C., Lopes, J.L., and Vergera, A.G., 1985, Phytochem., 24, 1, 203-204.

[12] Marsaioli, A.J., Reis, F., de A.M., Magalhaes, A.F., and Ruveda, E.A., 1979, Phytochem., 18, 165-169.

[13] Smolnycki, W.D., Maniot, J.L., Hindenlang, D.M., Miana, G.A., and Shamma, M., 1978, Tetrahedron Lett., 47, 4617-4620.

[14] Shamma, M., 1960, Experienta, 16, 484.

DOI: https://doi.org/10.22146/ijc.21516

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