THE ADDITION EFFECT OF SULPHANILIC ACID TO THE SYNTHESIS OF 3,4-METHYLENEDIOXYBENZALDEHYDE

https://doi.org/10.22146/ijc.21382

Feti Fatimah(1*), Sanusi Gugule(2)

(1) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Manado
(2) Department of Chemistry, Faculty of Mathematics and Natural Sciences, Manado State University
(*) Corresponding Author

Abstract


It was conducted a research about the addition effect of sulphanilic acid to the synthesis 3,4-methylenedioxybenzaldehyde from the isosafrole using reagents of sodium dichromate, sulphuric acid, and sulphanilic acid. The separation and purification of product were performed using the chromatography column. The purity of the result was tested using thin layer chromatography and determination of the melting point. Furthermore, it was identified its structure using infrared spectrophotometer, 1H and 13C nuclear magnetic resonance spectrometry, and mass spectrometry. The experimental result showed that the percentage yield of 3,4-methylenedioxybenzaldehyde with addition sulphanilic acid was 79.54%.

Keywords


3,4-methylenedioxybenzaldehyde; sulphanilic acid; isosafrole

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References

[1]   Freeman, S., and Alder, J.F., 2002, Eur. J. Med. Chem., 37, 7, 527–539.

[2]   Bjorsvik, H.R., Lucia, L., and Francesco, M., 2000, Org. Process Res. Dev., 4, 6, 534–543.

[3]   French, G., 1995, J. Chem. Educ., 72, 6, 485–489.

[4]   Zarzo, M., 2008, Food Qual. Preference, 19, 3, 315–322.

[5]   Grimshaw, J., and Hua, C., 1994, Electrochim. Acta, 39, 4, 497–499.

[6]   Torii, S., Uneyama, K., and Ueda, K., 1984, J. Org. Chem., 49., 1830–1832.

[7]   Salazar F.C., Avella-Moreno, E., and Cortés, M.T., 2007, J. Electroanal. Chem., 606, 1, 1–7.

[8]   Santos, A.S., Pereira, N.Jr., da Silva, I.M., Sarquis, M.I.M., and Antunes, O.A.C., 2004, Process Biochem., 39, 12, 2269–2275.

[9]   Borzatta, V., Capparella, E., Chiappino, R., Impala, D., and Vaccari, A., 2009, Catal. Today, 140, 1-2, 112–116.

[10] Harding, K.E., Leslie, M., and Kevin, F.D., 1975, J. Org. Chem., 40, 11, 1664–1665.

[11] Lee, D.G., and Udo, A.S., 1970, J. Org. Chem., 35, 10, 3589–3590.

[12] Awasthy, A.K., and Jan, R., 1969, J. Am. Chem. Soc., 91, 4, 991–996.

[13] Roberts, R.M., Gilbert, J.C., Rodewald, L.B., and Wingrove, A.S., 1978, Modern Experimental Organic Chemistry, 3Th Ed., Hott-Saunders Tokyo, 278–279.

[14] Poucher, W.A., 1974, Parfums, Cosmetics and Soap Vol.I, BI Publications, 330.

[15] Watanabe, K., Midori, M., Shizuka, F., Toshiyuki, K., Tamihide, M., and Ikuo, Y., 2001, J. Health Sci., 47, 3, 327–329.

[16] Stanfill, S.B., and Ashley, D.L., 1999, J. Chromatogr. A, 858, 1, 79–80.



DOI: https://doi.org/10.22146/ijc.21382

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