Dasril Basir(1*), Julinar Julinar(2)

(1) Department of Chemistry, Faculty of Science, University of Sriwijaya, Palembang 30662, South Sumatra
(2) Department of Chemistry, Faculty of Science, University of Sriwijaya, Palembang 30662, South Sumatra
(*) Corresponding Author


This paper describes 3-hydroxyurs-12-en-28-oic acid and its structural isomer 3-hydroxyolean-12-en-28-oic acid isolated from Fragraea fragrans fruits and their biological activities; anti-tumor, anti-inflammation, anti-microbial, and anti-fungal included their ultra violet photo-protective effect after exposed under sunlight radiation. They are useful for cosmetic ingredient. The above triterpenes are very promoting compounds for leukemia L1210 anti-tumor due to limited reports dealing with this type triterpenoid anti-tumor test. They significantly gave IC50 value of 5.78 µg/mL against leukemia L1210 cells, relatively closed to IC50 value of drugs, 4.0 µg/mL [12-13,17].


Isomeric; ursolic acid; oleanolic acid; Fragraea fragrans; cosmetic

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