EFFECTS OF DRYING METHODS IN GAINING OF EXTRACTIVE, PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY IN Gynura pseudochina (Lour.)

https://doi.org/10.22146/tradmedj.8065

Harrizul Rivai(1*), Hazli Nurdin(2), Hamzar Suyani(3), Amri Bakhtiar(4)

(1) Faculty of Pharmacy, University of Andalas
(2) Faculty of Mathematics and Science, University of Andalas
(3) Faculty of Mathematics and Science, University of Andalas
(4) Faculty of Pharmacy, University of Andalas
(*) Corresponding Author

Abstract


Effects of drying methods in gaining of extractive, phenolic content and antioxidant activity in Gynura pseudochina (Lour.) DC leaves have been investigated. The drying methods tested were air-drying at ± 25 oC, oven-drying at 40 OC,  oven-drying at 60 OC, microwave oven-drying and fresh samples as control. Results revealed that drying of the fresh plant caused the decrease of extractive obtainability, phenolic content and antioxidant activity. There were significant differences among drying methods (P < 0.05). Among the drying methods tested, the highest  extractive obtainability was by microwave oven-drying, whereas the highest phenolic concentration and antioxidant activity were by air-drying at ± 25 oC.


Keywords


Antioxidant; Gynura pseudochina (L.) DC; drying methods; phenolic compounds



References

Abdullah, T., 2005, Pengaruh pemberian ekstrak etanol daun dewa (Gynura pseudochina (Lour.) DC. terhadap kadar kolesterol total, kolesterol HDL, kolesterol LDL dalam serum tikus jantan hiperkolesterolemik, Tesis, Universitas Airlangga, Surabaya

Badan POM, 2004, Monografi Ekstrak Tumbuhan Obat Indonesia, Volume 1, Jakarta: Badan Pengawas Obat dan Makanan Republik Indonesia

Ditjen POM, 2000, Parameter Standar Umum Ekstrak Tumbuhan Obat, Jakarta: Departemen Kesehatan Republik Indonesia

Fu, P.P., Yang, Y.C., Xia, Q., Chou, M.W., Cui, Y.Y. and Lin, L., 2002, Pyrrolizidine alkaloids – tumorigenic components in Chinese herbal medicines and dietary supplements, J. Food and Drug Anal., 10(4), 198-211

Gaedcke, F., Steinhoff, B. and Blasius, H., 2003, Herbal Medicinal Products: Scientific and Regulatory Basis for Development, Quality Assurance and Marketing Authorisation, Stuttgart: Medpharm Scientific Publisher

Harmita, 2004, Petunjuk pelaksanaan validasi metode dan cara perhitungannya, Majalah Ilmu Kefarmasian, 1(3), 117-135

Herwindriandita, Kusmadiyani, S. dan Nawawi, A., 2006, Telaah fitokimia daun dewa (Gynura pseudochina (Lour.) DC., Skripsi, Sekolah Farmasi ITB, http://bahan-alam.fa.itb.ac.id (diakses tanggal 5 Mei 2009)

Mitra, S., and Brukh, R., 2003, Sample Preparation: An Analytical Perspective, in Sample Preparation Techniques in Analytical Chemistry, (Ed: Mitra, S.), New York: John Wiley & Sons, Inc., 1-36

Mosquera, O. M., Correa, Y.M., and Nino, J., 2009, Antioxidant activity of plants extract from Colombian flora, Braz. J. Pharmacogn., 19(2A), 382-387

Novayanti, D., 2009, Pengaruh ekstrak daun dewa (Gynura pseudochina (Lour.) DC., terhadap waktu perdarahan dan koagulasi pada tikus putih (Rattus norwegicus, L.) Skripsi, UIN Sunan Kalijaga, Yogyakarta

Perry, L.M. 1980. Medicinal Plants of East and South East Asia: Attributed Properties and Uses. Cambridge, M.A. : MIT Press

Pewnim, T., and Thadaniti, S., 1988, Study on medicinal plants of the Thachin basin with on emphasis on the chemical and biological properties, Research Summary: Silpakorn University No.3, Bangkok (Thailand), 158 p

Pewnim, T., 1993, Production of peroxidase from plants in the Thachin Basin, Research Abstracts Silpakorn University, Bangkok (Thailand), 156 p

Pourmorad, F., Hosseinimehr, S.J. and Shahabimajd, N., 2006, Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants, Afr. J. Biotechnol., 5(11),1142-1145

Qi, X., Wu, B., Cheng, Y., and Qu., H., 2009, Simultaneous characterization of pyrrolizidine alkaloids and N-oxides in Gynura segetum by liquid chromatography/ion trap mass spectrometry, Rapid Commun. Mass Spcrom., 23(2), 291-302

Sayuthi, D., Darusman, L.K., Suparto, I.H., Imanah, A., 2000, Potensi senyawa bioaktif daun dewa (Gynura pseudochina (Linn.) DC. sebagai antikanker, Tahap I, Buletin Kimia, 1(1), 23-29

Sayuthi, D., 2001, Ekstraksi, fraksinasi, karakterisasi dan uji hayati in vitro senyawa bioaktif daun dewa (Gynura pseudochina (Linn.) DC. sebagai antikanker, Tahap II, Buletin Kimia, 1(2), 75-79

Sudibyo, M., 1998, Alam Sumber Kesehatan: Manfaat dan Kegunaan, Jakarta: Balai Pustaka

WHO, 1998, Quality control methods for medicinal plant materials, Geneva: World Health Organization

Yuan, S.Q., Gu, G.M., and Wei, T.T., 1990, Studies on the alkaloids of Gynura segetum (Lour.) Merr., Yau Xue Xue Bao, 25(3), 191-197



DOI: https://doi.org/10.22146/tradmedj.8065

Article Metrics

Abstract views : 1690 | views : 46520

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2010 Majalah Obat Tradisional

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Majalah Obat Tradisional (Traditional Medicine Journal)
 ISSN 2406-9086
Faculty of Pharmacy
Universitas Gadjah Mada