APHRODISIAC EFFECTS OF RED GINGER (Zingiber officinale Rosc. red clone) ESSENTIAL OIL AND ESSENTIAL OIL FREE ETANOLIC EXTRACT IN MALE RATS

https://doi.org/10.22146/tradmedj.7999

Dipta Wana Anandita(1), Nurlaila Nurlaila(2), Suwijiyo Pramono(3*)

(1) Fakultas Farmasi, Universitas Gadjah Mada
(2) Fakultas Farmasi, Universitas Gadjah Mada
(3) Fakultas Farmasi, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Nowadays, many young men experience sexual disfunction due to many factors. Red ginger is  traditionally used to solve problems related to sexual disfunction. Oleoresin compound of red ginger has been reported to function as aphrodisiac. This research aims to compare aphrodisiac effect of  essential oil and essential oil free extract  in male rats. Red ginger essential oil was obtained by  destilation  while the red ginger free of essential oil was extracted using ethanol 70%. Rats were divided into five groups, administered by : etanolic extract suspension (140 mg/kg BM), essential oil emultion (15 μl/kg BM), pasak bumi extract suspension as positive control (500mg/kg BM), red ginger powder suspension as positive control (2,5 g/kg BM), and CMC Na 1% suspension as negative control. All rats were treated orally for 32 days. Parameters measured were introduction, climbing, and coitus frequency. The result showed that essential oil increased libido but its activity was lower  than pasak bumi.  Etanolic extract of red ginger and red ginger powder did not increase libido and sexual activity as compared with negative control.

Keywords


Aphrodisiac, red ginger, Zingiber officinale, coitus



References

Ang,H.H., Ngai, T.H., dan Tan, T.H., 2003, Effects of Eurycoma longifolia Jack on Sexual Qualities In Middle Aged Male Rats, Phytomedicine, 10, 590– 593

Anonim, 1986, Sediaan Galenik, 1,5-6,10-11, Departemen Kesehatan Republik Indonesia, Jakarta

Azis, S., Rahayu, T.R., 1996, Dasar Formulasi Jamu Majun / Kuat Pria,Cermin dunia Kedokteran, 112, 16-18

Gregoire, A., 1999, ABC of Sexual Health Assessing and Managing Male Sexual Problems, BMJ, 318, 315-317

Ippoushi, K., Azuma, K., Ito, H., Horie, H., dan Higashio, H., 2003, [6]-Gingerol inhibits nitric oxide synthesis in activated J774.1 mouse macrophages and prevents peroxynitrite-induced oxidation and nitration reactions, Life Sci, 73 (26), 3427-3437

Krinke, J.G., 2000, The Laboratory Rat (Handbook of Experimental Animals), 172-173, Academic Press, United States

Low, W.Y. dan Tan, H.M. , 2007, Asian Traditional Medicine for Erectile Dysfunction, J Men's Health & Gender, 4(3) , 245-250

Okata, J.M., Uboh, M., Obonga, W.O., 2008, Herb Drug Interaction : A Case Study of Effect Ginger on the Pharmacokinetics of Metronidazole in Rabbit, Indian J Pharm Sci, (70)2, 230-232

Setyowati, D., 2007, Pengaruh Pemberian Ekstrak Etanolik Rimpang Jahe Merah (Zingiber Officinale Roscoe var Rubrum) Terhadap Frequensi Minat dan Frequensi Koitus Tikus Putih Jantan Galur Wistar Sebagai Parameter Aprodisiaka, Skripsi, Fakultas Farmasi Universitas Setya Budi, Surakarta

Silalahi, J., 2005, Gas Nitrogen : Polutan atau Vital Bagi Kehidupan, Cermin Dunia Kedokteran, 147, 26-30

Suckow, M.A., Weisbroten, S.H., dan Franklin, C.L., 2006, The Laboratory Rat, second edition, 149-152, 166, Elsevier Inc, United States

Wagner, H., dan Bladt, S., 1984, Plant Drug Analysis : A Thin Layer Chromatograpy Atlas, Second Edition,300, Springer Verlag, Berlin

Yakubu, M.T., Akanji, M.A dan Oladiji, A.T, 2005, Aphrodisiac Potentials of the Aqueous Extract of Fadogia Agrestis (Schweinf. Ex Hiern) Stem In Male Albino Rats, Asian J Androl, 7 (4), 399–404



DOI: https://doi.org/10.22146/tradmedj.7999

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