Standardization of Phyllanthus niruri and Sonchus arvensis as Components of Scientific Jamu

https://doi.org/10.22146/mot.45955

Nikmatul Ikhrom Eka Jayani(1), Alfian Hendra Krisnawan(2), Nina Dewi Oktaviyanti(3), Kartini Kartini(4*)

(1) Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya
(2) Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya
(3) Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya
(4) 1) Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya 2) Centre for Information and Development of Traditional Medicine, University of Surabaya
(*) Corresponding Author

Abstract


Saintifikasi Jamu, or the scientific investigation of Jamu, is an evidence-based process to ensure the safety and efficacy of herbal medicine through health service research. Jamu has been empirically explored as a composition of various crude drugs, hence called as Scientific Jamu. Phyllanthus niruri and Sonchus arvensis are two of the 30 medicinal plants processed into Scientific Jamu. Components of the Scientific Jamu are standardized to ensure that these materials meet the predefined quality. This study was aimed to determine the specific parameters (macroscopic, microscopic, total flavonoid content, water-soluble extract content, and ethanol-soluble extract content) and non-specific parameters (loss on drying, total ash content, and acid insoluble ash content) of Phyllanthus niruri and Sonchus arvensis collected from Batu, Tawangmangu, and Bogor. The methods of the determination referred to the Indonesian Herbal Pharmacopoeia 1st Edition (2008). The results showed that Phyllanthus niruri and Sonchus arvensis from the three places did not meet the standard requirement.


Keywords


Standardization; Phyllanthus niruri; Sonchus arvensis; Scientific Jamu

Full Text:

PDF


References

Amessis-Ouchemoukh, N., Madani, K., Falé, PLV., Serralheiro, ML., Araújo, MEM., 2014, Antioxidant capacity and phenolic contents of some Mediterranean medicinal plants and their potential role in the inhibition of cyclooxygenase-1 and acetylcholinesterase activities, Industrial Crops and Products. 53(0):6-15.

Bagalkotkar, G., Sagineedu, S., Saad, M., Stanslas, J., 2006, Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review, Journal of Pharmacy and Pharmacology. 58(12):1559-70.

DEPKES RI, 2008, Farmakope Herbal Indonesia Edisi I. Departemen Kesehatan Republik Indonesia, Jakarta

DEPKES RI, 2000, Parameter standar umum ekstrak tumbuhan obat. Departemen Kesehatan Republik Indonesia, Jakarta

http://materiamedicabatu.jatimprov.go.id/ (accessed on April 1, 2020)

http://www.b2p2toot.litbang.kemkes.go.id/ (accessed on April 1, 2020)

https://ipb.ac.id/page/research/biopharmaca/ (accessed on April 1, 2020)

Jayani, NIE., Kartini., Putri, LK., 2020, Standardization of a Crude Drug Moringa oleifera Leaf from Africa, India and Local (Indonesian) which Cultivated in Bojonegoro Indonesia, International Journal of Pharmaceutical Research. 12 (2).

Krisyanella, K., Susilawati, N., Rivai, H., 2017, Pembuatan Dan Karakterisasi Serta Penentuan Kadar Flavonoid Dari Ekstrak Kering Herba Meniran (Phyllanthus niruri L.), Jurnal Farmasi Higea. 5(1):9-19.

Kumar, S., Pandey, AK., 2013, Chemistry and biological activities of flavonoids: an overview, The Scientific World Journal, 2013: 1-15

MENKES RI, 2010, Peraturan Menteri Kesehatan Republik Indonesia Nomor 003. MENKES/PER/2010 tentang saintifikasi jamu dalam penelitian berbasis pelayanan kesehatan. Menteri Kesehatan Republik Indonesia, Jakarta

MENKES RI, 2013, Peraturan Menteri Kesehatan Republik Indonesia Nomor 82 Tahun 2013. Menteri Kesehatan Republik Indonesia, Jakarta

Purwadianto, A., Poerwaningsih, E., Widiyastuti, Y., Neilwan, A., Sukasediati, N., 2017, Pedoman Penelitian Jamu Berbasis Pelayanan Kesehatan. Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan, Jakarta.

Seal, T., 2016, Quantitative HPLC analysis of phenolic acids, flavonoids and ascorbic acid in four different solvent extracts of two wild edible leaves, Sonchus arvensis and Oenanthe linearis of North-Eastern region in India, Journal of Applied Pharmaceutical Science, 6(2):157-66.

Tapas, AR., Sakarkar, D., Kakde, R., 2008, Flavonoids as nutraceuticals: a review, Tropical Journal of Pharmaceutical Research, 7(3):1089-99.

Triyono, A., 2016, Tujuh Ramuan Jamu Saintifik - Pemanfaatan Mandiri Oleh Masyarakat, Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan, Jakarta.

World Health Organization, 2011, Quality Control Methods for Herbal Materials. WHO Press, Geneva

Xia, Z., Liang, J., 2010, Steroids and phenols from Sonchus arvensis. Chinese Journal of Natural Medicines. 8(4):267-9.





DOI: https://doi.org/10.22146/mot.45955

Article Metrics

Abstract views : 3606 | views : 6586

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2020 Majalah Obat Tradisional

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Majalah Obat Tradisional (Traditional Medicine Journal)
 ISSN 2406-9086
Faculty of Pharmacy
Universitas Gadjah Mada