Hair Growth Promoting Activity of Green Tea Leaves (Camellia sinensis l.) Ethanolic Extract

Vini Noviani(1), Shelly Thauresia(2), Elsa Fitria Apriani(3), Partomuan Simanjuntak(4*)

(1) Magister of Pharmaceutical Sciences, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia
(2) Magister of Pharmaceutical Sciences, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia
(3) Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Sriwijaya University, South Sumatra, Indonesia
(4) Magister of Pharmaceutical Sciences, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia
(*) Corresponding Author


Hair loss and baldness is one of the abnormalities in the hair that often occurs in both men and women. Many cosmetic products from natural to synthetic materials have been developed to overcome these problems, yet, synthetics product is potential to give side effects, such as local irritation. In this study, green tea (Camellia sinensis L.) leaves were used as active substances. The aim of this study was to attest the hair growth promoting activity of n-hexane, water, and ethyl acetate fractions from ethanolic extract of green tea leaves. Green tea leaves contain flavonoids which can help promoting hair growth. To obtain the compound, green tea leaves were made into ethanolic extract. The extract was obtained by maceration using 70% ethanol then partitioned using n-hexane, ethyl acetate, and water, to obtain the n-hexane, ethyl acetate, and water fractions. Ethyl acetate and water fractions have been shown to contain flavonoids, so it could continue the hair growth promoting activities with concentrations of 1% and 4%. Hair growth promoting activity was performed on rabbits. The results showed that 4% of water fraction containing flavonoids had the best hair growth promoting activity.


Greentea leaves; hair growth promoting activity; water fraction; flavonoids

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Adhirajan, N., Kumar, D.V. & Gowri, C., 2008, ‘Development and Evaluation of Herbal Formulations for Hair Growth’, E-Journal Chem. 5, 34–38.

Departemen Kesehatan Republik Indonesia, 1995, Farmakope Herbal Indonesia, 1st ed, pp. 6, Direktur Jendral Badan Pengawas Obat dan Makanan, Jakarta.

Departemen Kesehatan Republik Indonesia, 2000, Parameter Standar Umum Ekstrak Tumbuhan Obat, pp. 6-9, Direktorat Pengawasan Tradisional, Direktorat Jenderal Pengawasan Obat dan Makanan, Jakarta

Esfandiari, A. & Kelly, A.P., 2005, ‘The effects of tea polyphenolic compounds on hair loss amoung rodents’, Journal of the National Medical Association. 97, 1165-1169.

Harborne, J.B., 1987, Metode Fitokimia, 2nd ed, translated by Kosasih Padmawinata & Iwang Soediro, pp. 147, Penerbit ITB, Bandung.

Harrison, S. & Bergfeld, W., 2009, ‘Diffuse hair loss: its triggers and management’, Clev Clin J Med. 76, 361–367.

Lamria, E., 2013, ‘Uji Stabilitas Fisik, Aktivitas, Dan Keamanan Dari Sediaan Hair Tonic Yang Mengandung Ekstrak Etanol Teh Hijau (Camellia sinensis L) sebagai Nutrasetika’, Skripsi, Fakultas Farmasi Universitas, Jakarta.

Markham, K.R., 1988, Cara Mengidentifikasi Flavonoid, translated by Kosasih Padmawinata & Sofi Niksolihin, pp. 65-75, Penerbit ITB, Bandung.

Tanaka, S., Saito, M. & Tabata, M., 1980, ‘Bioassay of Crude Drugs for Hair Growth Promoting Activity in Mice by a New Simple Method’, Planta Medica Suppl. 1, 84-89.

Thorat, R., 2010, ‘Herbal Treatment For Hair Loss’, Int J Pharm Technol. 2, 497–503.


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