DIOSGENIN DETERMINATION OF Costus speciosus WATER EXTRACT USING HPLC METHOD
Hari Susanti(1*), Subagus Wahyuono(2), Ratna Asmah Susidarti(3), Ika Puspita Sari(4)
(1) Faculty of Pharmacy, Ahmad Dahlan University, Yogyakarta
(2) Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(3) Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(4) Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author
Abstract
Keywords
Full Text:
PDF (Bahasa Indonesia)References
Abdelkarim A.S., Ali, B., Ali M., 2015, HPTLC determination of bioactive diosgenin for Sudanese and Indian fenugreek (Trigonellafoenum-graecum L.) seeds, International Journal of Advances in Pharmacy Medicine Bioallied Sciences , Vol 2, Issue 3:165-168.
Adnan and Pagarra, B., 2000, Effect of Rhizome Extract from Pacing (Costus speciosus, J.E Smith) on spermatogenesis mice (Mus musculus) ICR male, Research Report, Department of Biological Science, State University of Makassar.
Ahuja, S., Dong, M.W., 2005. Handbook of Pharmaceutical Analysis by HPLC, New York : Elsevier Academic Press. 6: 201-203.
Amir, M. , Mujeeb M., Sabih , A., Ahmad, S., Ahmad, A., Siddiqui, WA., 2010, Validation of HPTLC Method for Estimation of Diosgenin in Callus and Rhizome of Dioscorea deltoidea, Planta Medica; 76 :35.
Anonim, 2008, Farmakope Herbal edisi I, Departemen Kesehatan RI, Jakarta.
Anonim, 2009. The United State Pharmacopoeia : 32th Edition. USA : Pharmacopoieal Convention.
AOAC, 2012. Official Methods of Analysis 2012 : Guidelines for Standard Method Performance Requirements. Appendix F, . 9.
Chapagain , B., and Wiesman, Z., 2005, Variation in diosgenin level in seed kernels among different provenances of Balanites aegyptiaca Del (Zygophyllaceae) and its correlationwith oil content. African J. Biotech. Vol. 4 (11): 1209-1213.
Devi dan Urooj, 2010, Nutrient Profile and antioxidant component of Costus speciosus, Natural Product Resources, 1(1): 116-118
Eliza J., Daisy, P., Ignacimuthu, S., Duaripadiyan, V, 2009, Antidiabetic and Antilipidemic Effect of Eremanthin from Costus speciosus (koen)Sm. In STZ-induced diabetic rat, Chemico-Biological Interaction , 182 : 67-72.
Eliza J., Daisy, P., Ignacimuthu, S., 2010, Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm., Chemico-Biological Interaction, 188: 467-472.
Ghosh S, More P, Derle A, Patil AB, Markad P, et al.. 2014, Diosgenin from Dioscorea bulbifera: Novel Hit for Treatment of Type II Diabetes Mellitus with Inhibitory Activity against a-Amylase and a-Glucosidase. PLoS ONE 9(9): e106039 open access.
Joshi, B.N., Munat,H., Harkidar, M., Kulkarni, A.A., 2013,Orally Active Hypoglygemic protein from Costus igneus NE Br: An in vitro and in vivo Study, Biochemical and Biophysical Research Communication, 436:278-282.
Li, P., Mou Y, Lu, S., Sun , W., , Lou, J.,, Yin, C., and Zhou,L., 2012, Paper Quantitative determination of diosgenin in Dioscorea zingiberensis cell cultures by microplatespectrophotometry and high performance liquid chromatography, Af. J.Pharmacy Pharm. Vol. 6(15):1186 – 1193.
Qiao CF1, Li QW, Dong H, Xu LS, Wang ZT, 2002, Studies on Chemical Constituents of Two Plants from Costus, Zhongguo zhong Yao Zhi, 27(2):123-5 .
Selim, S. dan Al Jouni, S., 2015, Anticancer and apoptotic effects on cell proliferation of diosgenin isolated from Costus speciosus (Koen.) Sm. International Society for Complementary Medicine Research 15:301, DOI: 10.1186/s12906-015-0836-8, open access
Snyder, L.R., Kirkland, J.J., Dolan J.W., 2010. Introduction to Modern Liquid Chromatography, 3th Ed., USA:John Wiley & Sons, Inc. Publication.
Son, IS.,,Kim, J.H., Sohn, H.Y., Son, K.H., 2007, Antioxidative and Hypolipidemic Effect of Diosgenin, a Steroidal Saponin of Yam (Dioscorea spp) on High-Cholesterol Fed Rats, Biosci. Biotechnol. Biochem. 71 (12) : 3063-3071.
Susanti H, 2015, Potensi Pacing Sebagai antihiperkolesterol, Laporan Penelitian, UAD, Yogyakarta.
DOI: https://doi.org/10.22146/tradmedj.24171
Article Metrics
Abstract views : 5275 | views : 20558Refbacks
- There are currently no refbacks.
Copyright (c) 2017 Majalah Obat Tradisional
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Faculty of Pharmacy
Universitas Gadjah Mada