MUCOLYTIC IN VITRO ACTIVITY OF ETHANOLIC EXTRACT OF Hibiscus rosa-sinensis L. RED STRAIGHT CROWN

https://doi.org/10.22146/tradmedj.7749

Dinar Hesti Permatasari(1), Mimiek Murrukmihadi(2*)

(1) Faculty of Pharmacy, Universitas Gadjah Mada
(2) Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Ethanolic extract of red shoe flower (Hibiscus rosa-sinensis L.) has been known to decrease mucus viscosity by in vitro. The aim of this study is to evaluate the effect of various concentration of the extract in syrup for decreasing mucus viscosity and to evaluate the extract concentration which is equal with asetilsistein syrup 2.00%. Ethanolic extract was produced by maseration and made into five different concentration of syrup formula (1.00; 1.25; 1.50; 1.75 and 2.00%). The result showed that there is not any mucolytic activity from all of the formulas by decreasing mucus viscosity and there is not any formula as effective as mucolytic activity of asetilsistein 2.00%.


Keywords


mucolytic, syrup, ethanolic extract, red shoe flower



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DOI: https://doi.org/10.22146/tradmedj.7749

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