Antitussive Activity of Herbal Cough Medicine on Guinea Pigs (Cavia porvellus)
Zullies Ikawati(1), Poppy Firzani Arifin(2*), Severinus Nugraha Krisma Sandy(3), Raphael Aswin Susilowidodo(4), Rosalina Wisastra(5)
(1) Faculty of Pharmacy, Gadjah Mada University (UGM), Jl. Sekip Utara, Yogyakarta, Indonesia
(2) SOHO Centre of Excellence in Herbal Research (SCEHR), SOHO Global Health
(3) Faculty of Pharmacy, Gadjah Mada University (UGM), Jl. Sekip Utara, Yogyakarta, Indonesia SOHO Centre of Excellence in Herbal Research (SCEHR), SOHO Global Health
(4) SOHO Centre of Excellence in Herbal Research (SCEHR), SOHO Global Health
(5) SOHO Centre of Excellence in Herbal Research (SCEHR), SOHO Global Health
(*) Corresponding Author
Abstract
Keywords
Full Text:
PDFReferences
Agrawal DK, Bergren DR, Byorth PJ, Townley RG. 1991. Platelet- activating factor induces non-specific desensitization to bronchodilators in guinea pigs. J Pharmacol Exp Ther,259:1–7
Alam G, Wahyuono S., Ganjar IG, Hakim L, Timmerman H, Verpoort R. 2002. Tracheospasmolytic activity of Viteosin-A and VitexicarpinIsolated from Vitex trifolia L. Planta Medica 68 : 1047-1049.
Arifin PF, Suyatna FD,Arozal W, Wikanendra GB,Susilowidodo RA, Wisastra R.2020. Mucoactive Effect Evaluation and Acute Toxicity Study of Natural Herbal Combination of Echinacea purpurea, Sambucus nigra, Glycyrrhiza glabra, Vitex trifolia, and Zingiber officinale. Pharmacology Online, 1:186-194
Chen C, Zuckerman DM, Brantley S, Sharpe M, Childress K, Hoiczyk E, Pendleton AR. 2014. Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication. BMC Vet Res,10(1), 24.
Herdwiani W. 2011. Pengaruh Ekstrak Daun Legundi (Vitextrifolia, L) dan Rimpang Temulawak (Curcuma xanthorrhiza, Roxb) Terhadap Kadar IgE Total Serum dan Eosinofil Usapan Mukosa Hidung Penderita Rinitis Alergi, Tesis, Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta.
Hudson JB. 2012. Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases, J. Biom. Biotechnol., 769896.
Ikawati Z, Yuniarti N, Sudarman,K. 2009. Pengembangan formula ekstrak daun legundi (Vitex trifolia L) dan rimpang temulawak (Curcuma Xanthorrhiza Roxb) sebagai fitofarmaka untuk anti alergi, Laporan Penelitian Hibah Riset Peningkatan Kapasitas IPTEK dan Sistem Produksi, Yogyakarta. Ikawati Z. 2014. Penyakit Sistem Pernafasan dan Tatalaksana Terapinya. 1st ed.4th print. Bursa Ilmu, Yogyakarta,p 69.
Kuang Y, Li B, Fan J, Qiao X, Ye M. 2018. Antitussive and expectorant activities of licorice and its major compounds. Bioorg Med Chem. 26(1), 278-284
McGowan P., Jeffries A., Turley A. 2006. Crash Course: Respiratory System. 2nd ed. United Kingdom: Mosby. Rehman R., Akram M., Akhtar N., Jabeen Q., Shah, S.M.A. 2011. Zingiber officinale Roscoe (pharmacological activity ), J. Med. Plants Res., 5(3), 344-348.
Reynolds S.M.,Spina, D. & Page CP. 2003, Pharmacology of Peripherally Acting Antitussives in Chung KF., Widdicombe JG., Boushey HA., (Eds.), Cough: Causes, Mechanisms and Therapy, Blackwell Publishing Ltd., U.K, 237-246
Song KJ., Shin YJ., Lee, KR., Lee EJ., Suh, YS., Kim KS. 2015, Expectorant and Antitussive Effect of Hedera helix and Rhizoma coptidis Extracts Mixture, Yonsei Med. J., 56(3), 819-824.
Suekawa M., Ishige A., Yuasa K., Sudo K, Aburada M., Hosoya E.1984, Pharmacological studies on ginger. I. Pharmacological actions of pungent constitutents, (6)-gingerol and (6)-shogaol, J Pharmacobiodyn., 7(11):836-48
Weinberger SE. 2005. Cough and Hemoptysis. In: Kasper, DL., Braunwald, E., Fauci AS., Hauser SL., Longo DL., Jameson, JL., Harrison’s Principles of Internal Medicine. 16th ed. USA: McGraw Hill, 205-206.
Wisastra R, Arifin PF. 2020. Ex Vivo evaluation of the mucolytic effect from a natural herbal combination of Echinacea purpurea, Sambucus nigra, Glycyrrhiza glabra, Vitex trifolia, and Zingiber officinale. Res.J.Pharm.Biol.Chem.Sci; 11(1): 109-115
DOI: https://doi.org/10.22146/mot.56620
Article Metrics
Abstract views : 2258 | views : 5146Refbacks
- There are currently no refbacks.
Copyright (c) 2021 Majalah Obat Tradisional
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Faculty of Pharmacy
Universitas Gadjah Mada