COMPARISON OF PHYSICAL STABILITY PROPERTIES OF POMEGRANATE SEED OIL NANOEMULSION DOSAGE FORMS WITH LONG-CHAIN TRIGLYCERIDE AND MEDIUM-CHAIN TRIGLYCERIDE AS THE OIL PHASE
Sri Hartanti Yuliani(1*), Medaliana Hartini(2)
(1) Faculty of Pharmacy, Universitas Sanata Dharma
(2) Faculty of Pharmacy, Universitas Sanata Dharma
(*) Corresponding Author
Abstract
Keywords
Full Text:
PDF (Bahasa Indonesia)References
Affandi, M.M.M., Julianto, T., and Majeed, A., 2011, Development and Stability Evaluation of Astaxanthin Nanoemulsion, Asian J Pharm Clin Res, 4 (1):142-148.
Aslam, M.N., Lansky, E.P., Varani, J., 2006. Pomegranate as a cosmeceutical source: Pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. J. Ethnopharmacol. 103: 311–318.
Bouchemal, K., Briançon, S., Perrier, E., Fessi, H., 2004. Nano-emulsion formulation using spontaneous emulsification: Solvent, oil and surfactant optimisation. Int. J. Pharm. 280: 241–251.
Chen, H., Khemtong, C., Yang, X., Chang, X., Gao, J., 2011. Nanonization strategies for poorly water-soluble drugs. Drug Discov. Today 16: 354–360.
Davidov-Pardo, G., McClements, D.J., 2015. Nutraceutical delivery systems: Resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification. Food Chem. 167: 205–212.
Fletcher, P.D.I. and Suhling, K., 1998, Interaction Between Weakly Charged Oil in- Water Microemulsion Droplets, Langmuir, 14 (15): 4065-4069.
Gupta, P.K., Pandit, J.K., Kumar, A., Swaroop, P., and Gupta, S., 2010, Pharmaceutical Nanotechnology Novel Nanoemulsion-High Energy Emulsification Preparation, Evaluation and Application, T. Ph. Res., 3:117-138.
Huynh-Ba, K., 2009. Handbook of Stability Testing in Pharmaceutical Development. Springer New York. pp. 34
Ismail, T., Sestili, P., Akhtar, S., 2012. Pomegranate peel and fruit extracts: A review of potential anti-inflammatory and anti-infective effects. J. Ethnopharmacol. 143: 397–405.
Lansky, E.P., Newman, R.A., 2007. Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. J. Ethnopharmacol. 109: 177–206.
Mahdi, E.S., Noor, A.M., Sakeena, M.H., Abdullah, G.Z., Abdulkarim, M.F., Sattar, M.A., 2011. Formulation and in vitro release evaluation of newly synthesized palm kernel oil esters-based nanoemulsion delivery system for 30 % ethanolic dried extract derived from local Phyllanthus urinaria for skin antiaging. Int. J. Nanomedicine. 6: 2499–2512.
Melo, I.L.P., Carvalho, E.B.T. de;, Mancini-filho, J., 2014. Pomegranate Seed Oil (Punica granatum L .): A Source of Punicic Acid ( Conjugated α -Linolenic Acid ). J. Hum. Nutr. Food Sci. 2: 1–11.
Miguel, M.G., Neves, M. a, Antunes, M.D., 2010. Pomegranate (Punica granatum L.): A medicinal plant with myriad biological properties - A short review. J. Med. Plants Res. 4: 2836–2847.
Silva, A.P.C., Nunes, B.R., Oliveira, M.C., Koester, L.S., Mayogra, P., Bassani, V.L., et al., 2009, Development of Topical Nanoemulsions Containing the Isoflavone Genistein, Pharmazie, 64: 32-35.
Schubert, S.Y., Lansky, E.P., Neeman, I., 1999. Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids. J. Ethnopharmacol. 66: 11–17.
Suciati, T., Aliyandi, A., Satrialdi, 2014. Development of transdermal nanoemulsion formulation for simultaneous delivery of protein vaccine and artin-m adjuvant. Int. J. Pharm. Pharm. Sci. 6: 536–546.
Tadros, T., Izquierdo, P., Esquena, J., Solans, C., 2004. Formation and stability of nano-emulsions. Adv. Colloid Interface Sci. 108-109: 303–318.
Verardo, V., Garcia-Salas, P., Baldi, E., Segura-Carretero, A., Fernandez-Gutierrez, A., Caboni, M.F., 2014. Pomegranate seeds as a source of nutraceutical oil naturally rich in bioactive lipids. Food Res. Int. 65: 445–452.
Wooster, T.J., Golding, M., Sanguansri, P., 2008. Impact of oil type on nanoemulsion formation and Ostwald ripening stability. Langmuir 24: 12758–12765.
DOI: https://doi.org/10.22146/tradmedj.12823
Article Metrics
Abstract views : 4509 | views : 16007Refbacks
- There are currently no refbacks.
Copyright (c) 2016 Majalah Obat Tradisional
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Faculty of Pharmacy
Universitas Gadjah Mada