Application of Fuzzy Control in the Development of Electrical Stimulation to Accelerate Wound Healing

  • Rahmawati Program Sudi Teknologi Elektronika, Jurusan Teknik Elektro, Politeknik Negeri Lhokseumawe, Lhokseumawe, Aceh 24375, Indonesia
  • Achmad Arifin Departemen Teknik Biomedik, Fakultas Teknologi Elektro dan Informatika Cerdas, Institut Teknologi Sepuluh November, Surabaya, Jawa Timur 60111, Indonesia
  • Duti Sriwati Aziz Department of Anatomy Pathology, Faculty of Medicine, Hang Tuah University, Surabaya, Jawa Timur 60155, Indonesia
  • Gunawan Program Sudi Teknologi Rekayasa Mekatronika, Jurusan Teknik Elektro, Politeknik Negeri Lhokseumawe, Lhokseumawe, Aceh 24375, Indonesia
  • Raisah Hayati Program Sudi Teknologi Telekomunikasi, Jurusan Teknik Elektro, Politeknik Negeri Lhokseumawe, Lhokseumawe, Aceh 24375, Indonesia
  • Siti Amra Program Sudi Teknologi Elektronika, Jurusan Teknik Elektro, Politeknik Negeri Lhokseumawe, Lhokseumawe, Aceh 24375, Indonesia
Keywords: Electrical Stimulation, Fuzzy Logic, Wound Healing, Microcontroller

Abstract

Chronic wound healing, such as diabetic ulcers, requires an innovative approach, where electrical stimulation (ES) has proven effective but is still dominated by an open-loop system that is less adaptive. This study aims to develop a closed-loop electrical stimulation system based on fuzzy control that adjusts the stimulation duration dynamically. The system is designed by integrating an electrical stimulator, fuzzy control, and a wound area reduction model. The Atmega32 microcontroller is used to regulate stimulation with fuzzy control. Preclinical testing on experimental animals to compare the effectiveness of the control method (without therapy), open-loop, and closed-loop. The test results show that the electrical stimulator circuit works according to specifications, with a signal frequency of 20 Hz, a pulse width of 250 µs, and a boost converter output voltage of 50V. The error in the maximum stimulation duration is 2.5%, which is still within the safe limit for wound therapy. Fuzzy control is proven to be effective in adjusting the stimulation duration based on wound development, with an estimation error of only 0.3%. Preclinical testing showed that the fuzzy-controlled closed-loop system accelerated wound healing with a 64–67% reduction in wound area in seven days, higher than open-loop (44–50%) and no therapy (37.5%). Closed-loop also produced the highest tissue density (75–100%) compared to open-loop (50%) and no therapy (25–50%), proving its effectiveness in accelerating tissue regeneration. Fuzzy-controlled closed-loop electrical stimulation was able to accelerate wound healing up to 1.5 times faster than the open-loop method and almost twice as fast as no therapy. Fuzzy control adjusted the stimulation duration in real-time, avoiding over- and understimulation. This system is more effective than conventional methods and has the potential to increase the acceleration of wound healing.

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Published
2025-11-28
How to Cite
Rahmawati, Achmad Arifin, Duti Sriwati Aziz, Gunawan, Raisah Hayati, & Siti Amra. (2025). Application of Fuzzy Control in the Development of Electrical Stimulation to Accelerate Wound Healing. Jurnal Nasional Teknik Elektro Dan Teknologi Informasi, 14(4), 288-297. https://doi.org/10.22146/jnteti.v14i4.20232
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Articles