Pengaruh Medication Therapy Management terhadap Persepsi Sakit dan Outcome Klinik Pasien Diabetes Melitus di Puskesmas Kota Yogyakarta

https://doi.org/10.22146/jmpf.63876

Nanang Munif Yasin(1*), Tri Murti Andayani(2), Yanverty Idda Listyana(3)

(1) Faculty of Pharmacy UGM
(2) Faculty of Pharmacy UGM
(3) Magister Farmasi Klinik Faculty of Pharmacy UGM
(*) Corresponding Author

Abstract


Diabetes Melitus (DM) merupakan penyakit kronis yang komplek membutuhkan perawatan medis berkelanjutan dengan strategi pengurangan risiko multifaktorial di luar kendali glikemik. Penyakit DM memerlukan managemen terapi yang tepat, salah satu upaya yang diberikan adalah Medication Therapy Management (MTM). Pasien yang mendapatkan MTM memiliki persepsi sakit terhadap penyakitnya menjadi lebih baik dan akan berpengaruh pada hasil terapi. Penelitian ini bertujuan untuk mengetahui pengaruh pelayanan farmasi berbasis MTM terhadap persepsi sakit dan outcome klinik pada pasien diabetes melitus di Puskesmas Kota Yogyakarta pada periode Maret-April 2020. Jenis penelitian yang digunakan adalah quasi experimental one group with pretest and posttest design. Analisa menggunakan uji paired sample t-test dengan signifikansi yang digunakan P<0,05. Responden berjumlah 20 orang, merupakan pasien diabetes melitus tipe 2 yang memenuhi kriteria inklusi dan mendapatkan pelayanan farmasi berbasis MTM oleh apoteker berupa asesmen, edukasi, dan konseling. Hasil penelitian diperoleh skor persepsi sakit pasien terhadap penyakitnya yang diukur menggunalan brief illness perception questionnaire (BPI-Q), sebelum mendapatkan pelayanan MTM 49,95±10,41 menjadi 50,45± 10,06 (P=0.780). Outcome klinik berupa kadar glukosa darah puasa semula 128,66±43,99 mg/dL menjadi 129,96±23,46 mg/dL (P=0,876) setelah mendapatkan pelayanan berbasis MTM. MTM pada penelitian ini bisa meningkatkan skor persepsi sakit pasien terhadap penyakitnya meskipun belum berbeda bermakna, sedangkan hasil pemeriksaan kadar glukosa darah puasa pasien belum memberikan perbaikan outcome klinik pasien. Diperlukan penelitian dengan periode waktu yang lebih lama dan jumlah responden yang lebih banyak.  


Keywords


medication therapy management; diabetes melitus; persepsi sakit; outcome klinik; BIP-Q

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References

American Diabetes Association. Standars of Medical Care in Diabetes-2019. Diabetes Care. 2019;42:S1-S187.

Kementerian Kesehatan Republik Indonesia. Laporan Riset Kesehatan Dasar Indonesia Tahun 2018.; 2018.

Al-Tameemi NK, Sarriff A. Knowledge, attitude and practice of pharmacists on medication therapy management: a survey in Hospital Pulau Pinang, Penang, Malaysia. J Pharm Heal Care Sci. 2019;5(1):1-9. doi:10.1186/s40780-019-0131-9

Burns A. Medication therapy management in pharmacy practice: Core elements of an MTM service model (version 2.0). J Am Pharm Assoc. 2008;48(3):341-353. doi:10.1331/JAPhA.2008.08514

Notoatmojo. Promosi Kesehatan, Teori Dan Aplikasi. Rineka Cipta; 2010.

Broadbent E, Petrie KJ, Main J, Weinman J. The Brief Illness Perception Questionnaire. J Psychosom Res. 2006;60(6):631-637. doi:10.1016/j.jpsychores.2005.10.020

Strauss SM, Rosedale MT, Kaur N. Illness Perceptions Among Adults at Risk for Diabetes. Diabetes Educ. 2015;41(2):195-202. doi:10.1177/0145721715569003

Shallcross AJ, Becker DA, Singh A, et al. HHS Public Access. 2016;56(11):1-9. doi:10.1111/epi.13194.Illness

Martinez K, Lockhart S, Davies M, Lindsay JR, Dempster M. Diabetes distress, illness perceptions and glycaemic control in adults with type 2 diabetes. Psychol Heal Med. 2018;23(2):171-177. doi:10.1080/13548506.2017.1339892

Ashley L, Marti J, Jones H, Velikova G, Wright P. Illness perceptions within 6 months of cancer diagnosis are an independent prospective predictor of health-related quality of life 15 months post-diagnosis. Psychooncology. 2015;24(11):1463-1470. doi:10.1002/pon.3812

Masyithah N. Common Sense-Self Regulatory Model pada Pasien Diabetes Melitus Tipe 2 di RSUD Abdul Aziz Singkawang. Univ Ahmad Dahlan. Published online 2017.

Sinuraya RK, Oktrina A, Handayani NK, Destiani DP, Puspitasari IM. Pelayanan Farmasi Klinis Meningkatkan Kontrol Gula Darah Pasien Diabetes Melitus. Indones J Clin Pharm. 2019;8(4):271. doi:10.15416/ijcp.2019.8.4.271

Katadi S, Andayani TM, Endarti D. The Correlation of Treatment Adherence with Clinical Outcome and Quality of Life in Patients with Type 2 Diabetes. J Manaj DAN PELAYANAN Farm (Journal Manag Pharm Pract. 2019;9(1):19. doi:10.22146/jmpf.42927

Rokhman R, Darakay C, Raditya R. Pengaruh Pemberian Home Care Oleh Apoteker Pada Pasien Diabetes Melitus. J Manaj dan Pelayanan Farm. 2015;5(3):217-224.

Harreiter J, Kautzky-Willer A. Sex and gender differences in prevention of type 2 diabetes. Front Endocrinol (Lausanne). 2018;9(MAY):1-15. doi:10.3389/fendo.2018.00220

Raman B, Edelson GW. Lipid metabolism in women. Infertil Reprod Med Clin North Am. 2000;11(2):147-171. doi:10.1079/pns2003314

Ratna Saraswati M, Suastika K, Budhiarta A, Made Pande Dwipayana I. Hubungan Massa Lemak Tubuh Dengan Resistensi Insulin Pada Populasi Dengan Faktor Resiko Diabetes. Published online 2014. http://www.dtu.ox.ac.uk/Homacalculator/index.php.

Khan MZ. Mechanism linking diabetes mellitus and obesityAl-Goblan, Abdullah S. Al-Alfi, Mohammed A. Diabetes, Metab Syndr Obes Targets Ther. 2014;7:587-591.

Wild sarah roglic gojka. Estimates for the year 2000 and projections for 2030. World Health. 2004;27(5).

Chiu KC, Chu A, Go VLW, Saad MF. Hypovitaminosis D is associated with insulin resistance and β cell dysfunction. Am J Clin Nutr. 2004;79(5):820-825. doi:10.1093/ajcn/79.5.820

Ajabshir S, Asif A, Nayer A. The effects of vitamin D on the Renin-Angiotensin system. J Nephropathol. 2014;3(2):41-43. doi:10.12860/jnp.2014.09

Targher G, Bertolini L, Padovani R, et al. Serum 25-hydroxyvitamin D3 concentrations and carotid artery intima-media thickness among type 2 diabetic patients. Clin Endocrinol (Oxf). 2006;65(5):593-597. doi:10.1111/j.1365-2265.2006.02633.x

Tao X, Li J, Zhu X, et al. Association between socioeconomic status and metabolic control and diabetes complications: A cross-sectional nationwide study in Chinese adults with type 2 diabetes mellitus. Cardiovasc Diabetol. 2016;15(1):1-10. doi:10.1186/s12933-016-0376-7

Reagan LA, Walsh SJ, Shelton D. Relationships of illness representation, diabetes knowledge, and self-care behaviour to glycemic control in incarcerated persons with diabetes. Int J Prison Health. 2016;12(3):157-172. doi:10.1108/IJPH-04-2015-0010

Rasdianah N, Martodiharjo S, Andayani TM, Hakim L. The Description of Medication Adherence for Patients of Diabetes Mellitus Type 2 in Public Health Center Yogyakarta. Indones J Clin Pharm. 2016;5(4):249-257. doi:10.15416/ijcp.2016.5.4.249

Abougalambou SSI, Abougalambou AS. A study evaluating prevalence of hypertension and risk factors affecting on blood pressure control among type 2 diabetes patients attending teaching hospital in Malaysia. Diabetes Metab Syndr Clin Res Rev. 2013;7(2):83-86. doi:10.1016/j.dsx.2013.02.019

Kugbey N, Oppong Asante K, Adulai K. Illness perception, diabetes knowledge and self-care practices among type-2 diabetes patients: A cross-sectional study. BMC Res Notes. 2017;10(1):1-7. doi:10.1186/s13104-017-2707-5

Voigt A, Madrid E, Pacheco-Huergo V, et al. Association of glycaemia with perceived threat of illness in patients with type 2 diabetes. Prim Care Diabetes. 2015;9(6):426-431. doi:10.1016/j.pcd.2015.03.001

Michiels Y, Bugnon O, Chicoye A, et al. Impact of a Community Pharmacist-Delivered Information Program on the Follow-up of Type-2 Diabetic Patients: A Cluster Randomized Controlled Study. Adv Ther. 2019;36(6):1291-1303. doi:10.1007/s12325-019-00957-y

Ndefo UA, Moultry AM, Davis PN, Askew R. Provision of medication therapy management by pharmacists to patients with type-2 diabetes mellitus in a federally qualified health center. P T. 2017;42(10):632-637.

Zhu H, Zhu S, Zhang X, et al. Comparative efficacy of glimepiride and metformin in monotherapy of type 2 diabetes mellitus: Meta-analysis of randomized controlled trials. Diabetol Metab Syndr. 2013;5(1):1-11. doi:10.1186/1758-5996-5-70

Sahay RK, Mittal V, Gopal GR, et al. Glimepiride and Metformin Combinations in Diabetes Comorbidities and Complications: Real-World Evidence. Cureus. 2020;12(9). doi:10.7759/cureus.10700



DOI: https://doi.org/10.22146/jmpf.63876

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