* Corresponding Author
Pengukuran Kualitas Hidup Pasien Kanker Payudara di Kota Denpasar Menggunakan Instrumen EQ-5D-5L
https://doi.org/10.22146/jmpf.47192 Abdillah Mursyid(1), Restu Nur Hasanah Haris(2), Dwi Endarti(3*), Chairun Wiedyaningsih(4), Susi Ari Kristina(5)
(1) Graduate Program of Pharmacy Management, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(2) Institut Teknologi dan Kesehatan Avicena, Kendari
(3) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(4) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(5) Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author
Abstract
Breast cancer is the second most common cancer in the world and is one of the biggest causes of cancer deaths every year. Measurement of the quality of life in breast cancer patients could improve treatment and become a prognosic factor along with medical parameters for the patients. This study aims to measure the life quality of breast cancer patients and observe how it affects the life quality based on patient characteristics. The study was conducted on 93 breast cancer patients. Data were collected form patients in several breast cancer comunities in Denpasar which were carried outh within 3 months (January – March 2019). This study used a cross sectional design using a snowball sampling technique involving breast cancer patients in several cancer communities in Denpasar. The patient's life quality data was obtained using the EuroQol-5 Dimension-5 Level (EQ-5D-5L) generic instrument and conversion to health utility (utility) used the Indonesian value set. The entire data was analyzed using the independent t-test and multivariate regression. The results showed that pain/discomfort and anxiety/depression were the most dominant problem in breast cancer patients (82,7%). The utility value of breast cancer patients was 0.821±0.123 and the VAS value was 74.41±11.67. There was a significant difference in utility value based on patient characteristics of occupation (p=0.035), symptoms (p=0,003), and cancer stadium (p=0.015). Affected 20.5% of the quality of life of breast cancer patients in Denpasar city.
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1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424. doi:10.3322/caac.21492
2. Kementerian Kesehatan Republik Indonesia. Riset Kesehatan Dasar. 2013.
3. Canário ACG, Cabral PUL, Paiva LC de, Florencio GLD, Spyrides MH, Gonçalves AK da S. Physical activity, fatigue and quality of life in breast cancer patients. Rev Assoc Médica Bras. 2016;62(1):38-44. doi:10.1590/1806-9282.62.01.38
4. Ataollahi Mr, Sharifi J, Paknahad MR. Breast cancer and associated factors: A review. J Med Life. 2015;8(4):6.
5. Chen Q, Li S, Wang M, Liu L, Chen G. Health-Related Quality of Life among Women Breast Cancer Patients in Eastern China. BioMed Res Int. 2018;2018:1-12. doi:10.1155/2018/1452635
6. Setyowibowo H, Purba FD, Hunfeld JAM, et al. Quality of life and health status of Indonesian women with breast cancer symptoms before the definitive diagnosis: A comparison with Indonesian women in general. Lin C-Y, ed. PLOS ONE. 2018;13(7):e0200966. doi:10.1371/journal.pone.0200966
7. Devlin NJ, Brooks R. EQ-5D and the EuroQol Group: Past, Present and Future. Appl Health Econ Health Policy. 2017;15(2):127-137. doi:10.1007/s40258-017-0310-5
8. Devlin NJ, Krabbe PFM. The development of new research methods for the valuation of EQ-5D-5L. Eur J Health Econ. 2013;14(Suppl 1):1-3. doi:10.1007/s10198-013-0502-3
9. Rautalin M, Färkkilä N, Sintonen H, et al. Health-related quality of life in different states of breast cancer – comparing different instruments. Acta Oncol. 2018;57(5):622-628. doi:10.1080/0284186X.2017.1400683
10. Kimman ML, Dirksen CD, Lambin P, Boersma LJ. Responsiveness of the EQ-5D in breast cancer patients in their first year after treatment. Health Qual Life Outcomes. 2009;7(1). doi:10.1186/1477-7525-7-11
11. Rukminingsih F, Andayani TM, Rahmawati F, Widayati K. HEALTH-RELATED QUALITY OF LIFE IN EARLY BREAST CANCER PATIENTS WITH HORMONE RESPONSIVE. Int J Pharm Pharm Sci. December 2018:47-49. doi:10.22159/ijpps.2018v10i12.29648
12. Purba FD, Hunfeld JAM, Iskandarsyah A, et al. The Indonesian EQ-5D-5L Value Set. PharmacoEconomics. 2017;35(11):1153-1165. doi:10.1007/s40273-017-0538-9
13. Kementerian Kesehatan Republik Indonesia. InfoDATIN “Bulan Peduli Kanker Payudara.” Indonesia; 2016:1-12.
14. Sugiyono. Metode Penelitian Pendidikan: Pendekatan Kuantitatif, Kualitatif Dan R &D. Bandung: Alfabeta; 2010.
15. Ganesh S, Lye M-S, Lau FN. Quality of Life among Breast Cancer Patients In Malaysia. Asian Pac J Cancer Prev. 2016;17(4):1677-1684. doi:10.7314/APJCP.2016.17.4.1677
16. Chen H, Zhou M, Tian W, Meng K, He H. Effect of Age on Breast Cancer Patient Prognoses: A Population-Based Study Using the SEER 18 Database. Coleman WB, ed. PLOS ONE. 2016;11(10):e0165409. doi:10.1371/journal.pone.0165409
17. Wang K, Li X, Zhou C, Ren Y, Wang X-B, He J-J. Socio-economic Factors Influencing Tumor Presentation and Treatment Options in Chinese Breast Cancer Patients. Asian Pac J Cancer Prev. 2013;14(1):267-274. doi:10.7314/APJCP.2013.14.1.267
18. Matalqah LM, Radaideh KM, Yusoff ZM, Awaisu A. Health-related quality of life using EQ-5D among breast cancer survivors in comparison with age-matched peers from the general population in the state of Penang, Malaysia. J Public Health. 2011;19(5):475-480. doi:10.1007/s10389-011-0406-6
19. Li S, Wang M, Liu L, Chen G. Which approach is better in eliciting health state utilities from breast cancer patients? Evidence from mainland China: XXXX. Eur J Cancer Care (Engl). 2019;28(2):e12965. doi:10.1111/ecc.12965
20. Hashemi S-M, Balouchi A, Al-Mawali A, et al. Health-related quality of life of breast cancer patients in the Eastern Mediterranean region: A systematic review and meta-analysis. Breast Cancer Res Treat. 2019;174(3):585-596. doi:10.1007/s10549-019-05131-0
21. Abu Farha NH, Khatib MT, Salameh H, Zyoud SH. Cancer-related post-treatment pain and its impact on health-related quality of life in breast cancer patients: A cross sectional study in Palestine. Asia Pac Fam Med. 2017;16(1). doi:10.1186/s12930-017-0037-3
22. Yfantis A, Intas G, Tolia M, et al. Health-related quality of life of young women with breast cancer. Review of the literature. JBUON. 2018;23:6.
23. Gangane N, Khairkar P, Hurtig A-K, Sebastián MS. Quality of Life Determinants in Breast Cancer Patients in Central Rural India. Asian Pac J Cancer Prev. 2017;(12). doi:10.22034/APJCP.2017.18.12.3325
24. Sani A, Naab F, Aziato L. Influence of educational level on knowledge and practice of breast self-examination among women in Sokoto, Nigeria. J Basic Clin Reprod Sci. 2016;5(2):100. doi:10.4103/2278-960X.194482
25. Gurdal SO, Saracoglu GV, Oran ES, Yankol Y, Soybir GR. The Effects of Educational Level on Breast Cancer Awareness: A Cross-Sectional Study in Turkey. Asian Pac J Cancer Prev. 2012;13(1):295-300. doi:10.7314/APJCP.2012.13.1.295
26. Al-Jabi SW, Yahya R, Salameh R, et al. Health-related quality of life in patients with breast cancer in Palestine: An assessment of a cross-sectional study using the EuroQoL-5 dimensions scale. The Lancet. 2018;391:S34. doi:10.1016/S0140-6736(18)30359-3
27. Shi J-F, Huang H-Y, Guo L-W, et al. Quality-of-life and health utility scores for common cancers in China: A multicentre cross-sectional survey. The Lancet. 2016;388:S29. doi:10.1016/S0140-6736(16)31956-0
DOI: https://doi.org/10.22146/jmpf.47192
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