* Corresponding Author
Secondary acute myeloblastic leukemia after adjuvant chemotherapy and radiotherapy in breast cancer: A case report
https://doi.org/10.19106/JMedScie004603201405 Mardiah Suci Hardianti(1*), Johan Kurnianda(2), Kartika Widayati Taroeno-Hariadi(3)
(1) Division of Hematology-Medical Oncology, Department of Internal Medicine, Dr. Sardjito General Hospital/ Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia
(2) Division of Hematology-Medical Oncology, Department of Internal Medicine, Dr. Sardjito General Hospital/ Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia
(3) Division of Hematology-Medical Oncology, Department of Internal Medicine, Dr. Sardjito General Hospital/ Faculty of Medicine Universitas Gadjah Mada, Yogyakarta, Indonesia
(*) Corresponding Author
Abstract
A rising number of long-term survivors and potential long-term outcome related to the treatment is
one of the most important issue due to the advances of management in cancer. The development of
secondary malignancy has been reported in a number of cohorts. We present a case of breast cancer
patient developing acute myeloid leukemia (AML)- M5 within a relatively short interval of two and a
half years from her primary treatment with adjuvant chemotherapy with 4 cycles of doxorubicin and
cyclophosphamide, followed by 4 cycles of three weekly paclitaxel (AC-T) and radiotherapy. What
could be attributed to the occurrence of secondary leukemia in this patient will be discussed.
one of the most important issue due to the advances of management in cancer. The development of
secondary malignancy has been reported in a number of cohorts. We present a case of breast cancer
patient developing acute myeloid leukemia (AML)- M5 within a relatively short interval of two and a
half years from her primary treatment with adjuvant chemotherapy with 4 cycles of doxorubicin and
cyclophosphamide, followed by 4 cycles of three weekly paclitaxel (AC-T) and radiotherapy. What
could be attributed to the occurrence of secondary leukemia in this patient will be discussed.
Keywords
breast cancer- secondary leukemia- adjuvant chemotherapy-radiotherapy-breast cancer
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PDF DOI: https://doi.org/10.19106/JMedScie004603201405
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