The impact of COVID-19 pandemic on decreasing hospitalization rates and management of acute coronary syndrome: a study from single centre hospital in Yogyakarta, Indonesia

https://doi.org/10.19106/JMedSci005502202303

Hendry Purnasidha Bagaswoto(1), Ferdinandus Bayu Satria(2), Hani Khairina(3), Nahar Taufik(4*), Budi Yuli Setianto(5)

(1) Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital
(2) Resident of Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital
(3) Research Assistant of Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia
(4) Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital
(5) Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital
(*) Corresponding Author

Abstract


The Corona virus disease-2019 (COVID-19) pandemic has an impact on the medical field, one of which is service for patients with acute coronary syndrome (ACS). Studies in other countries showed a sudden decrease in admission rates, and percutaneous coronary intervention (PCI), one of ACS treatments, has an impact due to this pandemic. This study aimed to ascertain the effect of COVID-19 on the admissions and management of patients with ACS in Yogyakarta, Indonesia. It was an observational single center study conducted by collecting data for ACS patients at Dr. Sardjito General Hospital, Yogyakarta. Admission data for March 2019 to February 2020 were pre pandemic data, while those gathered from March to December 2020 were pandemic data. Data from 864 (pre pandemic period) and 338 patients (during the pandemic period) were further analyzed. The results showed a decrease in ACS patients’ admission during the pandemic. The most remarkable reduction occurred in those with ST-segment elevation myocardial infarction (STEMI), followed by non-STEMI (NSTEMI) and unstable angina pectoris (UAP) (63.4, 61.4, and 40.9%, respectively). Furthermore, the PCI procedure decreased compared to the period before the pandemic. No significant differences in patients’ characteristics was observed (p>0.05), except for the incidence of pneumonia (p <0.001). Finally, the mortality rate was higher during the pandemic than before (14.8 vs 13.2%), although it was not significant (p>0.05). This study showed that COVID-19 caused a sensible reduction in the admission rates for ACS patients and the number of PCI procedures have been performed. On the other hand, their mortality rate did not increase significantly. However, it is essential to improve healthcare services for ACS patients considering the uncertainty of ending the COVID-19 outbreak.


Keywords


COVID-19 pandemic;admission rates;management;acute coronary syndrome

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References

Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet 2003; 361(9351):13-20.
https://doi.org/10.1016/S0140-6736(03)12113-7
2.Araiza-Garaygordobil D, Montalto C, Martinez-Amezcua P, Cabello-Lopez A, Gopar-Nieto R, Alabrese R, et al. Impact of the COVID-19 pandemic on hospitalizations for acute coronary syndromes: a multinational study. QJM 2021;114(9):642-7.
https://doi.org/10.1093/qjmed/hcab013
3.Guha S, Mukhopadhay S, Karak A, Choudhury B, Kapoor A, Yadav R. Managing ACS during COVID-19 infection: Do not follow the traditional route. Indian Heart J 2020; 72(2):128-30.
https://dpoi.org/10.1016/j.ihj.2020.04.003
4.Jing ZC, Zhu HD, Yan XW, Chai WZ, Zhang S. Recommendations from the Peking Union Medical College Hospital for the management of acute myocardial infarction during the COVID-19 outbreak. Eur Heart J 2020; 41(19):1791-4.
https://doi.org/10.1093/eurheartj/ehaa258
5.Zhang L, Fan Y, Lu Z. Experiences and lesson strategies for cardiology from the COVID- 19 outbreak in Wuhan, China, by “on the scene” cardiologist. Eur Heart J 2020; 41(19):1788–90.
https://doi.org/10.1093/eurheart/ehaa266
6.Center for System Science and Engineering at John Hopkins University. Coronavirus Resource Center. [cited 2020, January 2nd] Available from: https://coronavirus.jhu.edu/
7.World Health Organization Regional Office for Europe. WHO Announces COVID-19 Outbreak Pandemic. [cited 2020, January 2nd]. Available from: http://www. euro.who.int/en/health-topics/health-emergencies/corona virus-covid-19/news/news/2020/3/ who-announces-covid-19- outbreak-a-pandemic
8.Bhatt AS, Moscone A, McElrath EE, Varshney AS, Claggett BL, et al. Fewer hospitalizations for acute cardiovascular conditions during the COVID-19 pandemic. J Am Coll Cardiol 2020; 76(3):280-8.
https://doi.org/10.1016/j.jacc.2020.05.038
9.Calvão J, Amador AF, Costa CMD, Araújo PM, Pinho T, Freitas J, et al. The impact of the COVID-19 pandemic on acute coronary syndrome admissions to a tertiary care hospital in Portugal. Rev Port Cardiol 2022;41(2):147-52.
http:s//doi.org/10.1016/j.repc.2021.01.007
10.de Filippo O, D'Ascenzo F, Angelini F, Bocchino PP, Conrotto F, Saglietto A, et al. Reduced rate of hospital admissions for ACS during Covid-19 outbreak in Northern Italy. N Engl J Med 2020;383(1):88-9.
https://doi.org/10.1056/NEJMc2009166
11.Metzler B, Siostrzonek P, Binder RK, Bauer A, Reinstadler SJ. Decline of acute coronary syndrome admissions in Austria since the outbreak of COVID-19: the pandemic response causes cardiac collateral damage. Eur Heart J 2020; 41(19):1852-3.
https://doi.org/10.1093/eurheartj/ehaa314
12.Solomon MD, McNulty EJ, Rana JS, Leong TK, Lee C, Sung SH, et al. The Covid-19 pandemic and the incidence of acute myocardial infarction. N Engl J Med 2020; 383(7):691-3.
https://doi.org/10.1056/NEJMc2015630
13.de Rosa S, Spaccarotella C, Basso C, Calabro MP, Curcio A, Filardi PP, et al. Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era. Eur Heart J 2020; 41(22):2083-8.
https://doi.org/10.1093/eurheartj/ehaa409
14.Pessoa-Amorim G, Camm CF, Gajendragadkar P, De Maria GL, Arsac C, Laroce C, et al. Admission of patients with STEMI since the outbreak of the COVID-19 pandemic: a survey by the European Society of Cardiology. Eur Heart J Qual Care Clin Outcomes 2020; 6(3):210-6.
https://doi.org/10.1093/ehjqcco/qcaa046
15.Mafham MM, Spata E, Goldacre R, Gair D, Curnow P, Bray M, et al. COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England. Lancet 2020; 396(10248):381-89.
https://doi.org/10.1016/S0140-6736(20)31356-8
16.Matsushita K, Hess S, Marchandot B, Sato C, Truong DP, Kim NT, et al. Clinical features of patients with acute coronary syndrome during the COVID-19 pandemic. J Thromb Thrombolysis 2021; 52(1):95-104.
https://doi.org/10.1007/s11239-020-02340-z
17.Garcia S, Stanberry L, Schmidt C, Sharkey S, Megaly M, Albaghdadi MS, et al. Impact of COVID-19 pandemic on STEMI care: an expanded analysis from the United States. Cathether Cardiovasc Interv 2021; 98(2):217-22.
https://doi.org/10.1002/ccd.29154
18.Lin Z, Yongzhen F, Zhibing L. Experiences and lesson strategies for cardiology from the COVID-19 outbreak in Wuhan, China, by ‘on the scene’ cardiologists. Eur Heart J 2020; 41(19):1788-90.
https://doi.org10.1093/eurheartj/ehaa266



DOI: https://doi.org/10.19106/JMedSci005502202303

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