The difference of Natural Killer cell activities of the people live in the aircraft noise area of Adi Soemarmo Airport Boyolali, Surakarta, Indonesia

Abstract

Exposure to noises contributes to a health risk. There is sufficient scientific evidence that noise exposure could
induce hearing impairment, hypertension and ischemic heart disease, annoyance, sleep disturbances, and decreased
school performance. Other evidence as changes in the immune system and birth defects is limited. The aims of this
study is to find out the difference of Natural Killer (NK) cell activities of the people live in the aircraft noise area of
Adi Sumarmo Airport, Boyolali, Surakarta, Indonesia. The research design was an analytical with a cross sectional
approach, taking location at the Dibal and Gagak Sipat Villages, Ngemplak Sub district, Boyolali District. The study
was conducted from June 2008 to June 2009. The number of subjects involved was 39. They were divided into 3
groups. Group 1 was exposed to 52.17 dB of noise level (13 respondents). Group 2 was exposed to 71.79 dB of
noise level (13 respondents), and Group 3was exposed to 92.29 dB of noise level (13 respondents). The cytotoxicities
of NK cells was measured by flowcytometric and using a non-radioactive method. The samples were taken using a
simple random sampling. The data were analyzed by Anova followed by Post Hoc Test using LSD test completed
with Homogenous Subsets. The results showed that the activity of NK cells of Group 1, 2 and 3 were 12.50 +
3.25%,17.20 3.06%, and 22.33 6.30 %, respectively. The Anova test showed that there was a significant
difference of NK cell activities, in the groups of respondents (p =0.000). In conclusion, there was a significant
difference of the NK cell activities of the people live in the aircraft noise area of Adi Sumarmo Airport, Boyolali,
Surakarta, Indonesia.
Key words : noise-immune system-flowcytometric-blood mononuclear cells-health risk