The optimization of ultrasonic method for the extraction of Pumpkin seed (Cucurbita maxima)

  • Irnawati Irnawati Fakultas Farmasi, Universitas Halu Oleo Kendari, Sulawesi Tenggara 93232 Indonesia
  • Sugeng Riyanto Departemen Kimia Farmasi, Fakultas Farmasi, Universitas Gadjah Mada, Jalan Sekip Utara, Sendowo, Sinduadi, Mlati, Sleman, 55281, Yogyakarta
  • Sudibyo Martono Departemen Kimia Farmasi, Fakultas Farmasi, Universitas Gadjah Mada, Jalan Sekip Utara, Sendowo, Sinduadi, Mlati, Sleman, 55281, Yogyakarta
  • Abdul Rohman Departemen Kimia Farmasi, Fakultas Farmasi, Universitas Gadjah Mada, Jalan Sekip Utara, Sendowo, Sinduadi, Mlati, Sleman, 55281, Yogyakarta
DOI: https://doi.org/10.22146/ijcpa.527
Keywords: pumpkin seed oil, The Box Behnken design (BBD), optimize, ultrasonic-assisted extraction

Abstract

The purpose of the present study was to determine the optimal ultrasound-assisted extraction (UAE) conditions (sample-to-solvent ratio, ultrasonic power, and time) for the extraction of pumpkin seed oil.  Pumpkin seed oil was analyzed for yield, 2.2’-Diphenyl-1-picrylhydrazyl (DPPH) scavenging activity, and total phenolic content.  Soxhlet extraction methods were assessed for comparison.  The Box Behnken design (BBD) was applied to optimize UAE conditions.  The optimum UAE conditions were obtained using sample-to-solvent ratio of 1:10 mL g-1, ultrasonic power of 150 Watt in 15 min extraction time.  Compared with Soxhlet extraction methods, UAE exhibited lower oil yield and total phenolic content but had higher DPPH scavenging activity.  The advantage of ultrasonic-assisted extraction was clearly reduction of extraction duration.

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Published
2021-02-14
How to Cite
Irnawati, I., Riyanto, S., Martono, S., & Rohman, A. (2021). The optimization of ultrasonic method for the extraction of Pumpkin seed (Cucurbita maxima). Indonesian Journal of Chemometrics and Pharmaceutical Analysis, 1(1), 42-51. https://doi.org/10.22146/ijcpa.527
Issue
Vol 1 No 1 (2021)
Section
Original Articles
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