Antioxidant Activity of Temulawak (Curcuma xanthorrhiza Roxb.) and its Classification with Chemometrics

  • Indah Widyastuti Departemen Kimia Farmasi, Fakultas Farmasi, Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia
  • Hanna Zaidah Luthfah Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia
  • Yuniar Intan Hartono Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia
  • Rosy Islamadina Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia
  • Adelin Theresia Can Fakultas Farmasi Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia
  • Abdul Rohman Departemen Kimia Farmasi, Fakultas Farmasi, Universitas Gadjah Mada, Jalan Sekip Utara, Sendowo, Sinduadi, Mlati, Sleman, 55281, Yogyakarta
DOI: https://doi.org/10.22146/ijcpa.507
Keywords: chemometric, antioxidant, flavonoid, phenolic

Abstract

Temulawak (Curcuma xanthorrhiza Roxb.) or Javanese turmeric is one of the medicine plants from Indonesia, which contains curcuminoid and xanthorrhizol. These compounds have large biological activity, such as antioxidant capacity. The location of this plant grows, affects the variance of the active compound which causes the changes in its activity. This study aims to evaluate antioxidant capacity, total phenolic, and total flavonoid content (TPC and TFC) of the sample collected from different markets, and to classify the samples into different culsters with chemometric techniques. The antioxidant capacity is determined by using DPPH radical scavenging assay, meanwhile, TPC and TFC are determined by Folin-Ciocalteu and AlCl3 method using Spectrophotometry UV/Vis. These data were used to analyze the samples with chemometric principal component analysis (PCA) and cluster analysis (CA) to classify the samples into different clusters. Sample TL02 (Sambi Market, Kediri, East Java) has the highest phenolic-flavonoid content and antioxidant capacity. Clustering samples based on PCA and CA resulting in 3 clusters.

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Published
2021-02-14
How to Cite
Widyastuti, I., Luthfah, H. Z., Hartono, Y. I., Islamadina, R., Can, A. T., & Rohman, A. (2021). Antioxidant Activity of Temulawak (Curcuma xanthorrhiza Roxb.) and its Classification with Chemometrics. Indonesian Journal of Chemometrics and Pharmaceutical Analysis, 1(1), 28-41. https://doi.org/10.22146/ijcpa.507
Issue
Vol 1 No 1 (2021)
Section
Original Articles
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