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* Corresponding Author
Potensi kombinasi ekstrak buah bit dan virgin coconut oil dalam disclosing toothpaste
https://doi.org/10.22146/mkgk.60758 Rifki Kurniasari(1), Sevina Dwi Oktaviani(2), Eka Anis Rahayuningsih(3), Archadian Nuryanti(4*)
(1) Pendidikan Dokter Gigi, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta
(2) Pendidikan Dokter Gigi, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta
(3) Pendidikan Dokter Gigi, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta
(4) Departemen Biomedika, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author
Abstract
Akumulasi plak gigi dapat menyebabkan karies dan penyakit periodontal. Disclosing agent, sediaan yang dapat memvisualisasikan plak gigi, dapat dikombinasikan dengan pasta gigi menjadi disclosing toothpaste. Buah bit (Beta vulgaris) sering digunakan sebagai pewarna alami sedangkan Virgin Coconut Oil (VCO) memiliki efek antimikroba. Keduanya berpotensi digunakan sebagai bahan disclosing toothpaste. Penulisan studi literatur bertujuan untuk memberikan kajian mengenai potensi kombinasi ekstrak buah bit dan Virgin Coconut Oil dalam disclosing toothpaste. Literatur yang digunakan sebagai sumber referensi berupa jurnal dan artikel ilmiah yang tersedia di PubMed, Science Direct, dan Google Scholar berdasarkan kata kunci yang telah ditentukan. Berdasarkan studi literatur, ditemukan bahwa buah bit mengandung pigmen betalain yang berfungsi sebagai indikator perubahan pH melalui warna yang ditimbulkannya. Di sisi lain, asam laurat dalam VCO memiliki aksi antibakteri dengan merusak integritas membran sel serta menghambat enzim yang berperan dalam proses metabolisme dan transfer nutrisi sel. Selain itu, VCO mengandung asam kaprat sebagai antifungi yang dapat menghambat adhesi fungi serta menyebabkan kerusakan seluler. Oleh karena itu, kombinasi ekstrak buah bit dan Virgin Coconut Oil sebagai agen antimikroba berpotensi untuk digunakan menjadi bahan disclosing toothpaste.
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1. Keerthana R, Jeevanandan G. Recent developments in dental plaque. Drug Invention
Today. 2018; 10(1): 2769-2772.
2. Listyasari NA, Santoso O. Inhibition of dental plaque formation by toothpaste containing
propolis. Dental Journal (Majalah Kedokteran Gigi). 2012; 45(4): 2018-2211.
doi: 10.20473/j.djmkg.v45.i4.p208-211
3. Seneviratne CJ, Zhang CF, dan Samaranayake LP. Dental plaque biofilm in oral health and
disease. Chin J Dent Res. 2011; 14(2): 87-94.
4. Prasanth M. Antimicrobial efficacy of different toothpastes and mouthrinses: an in vitro study.
Dent Res J (Isfahan). 2011; 8(2): 85–94.
5. Nightingale KJ, Chinta SK, Agarwal P, Nemelivzky M, Frisina AC, Cao Z, Norman RG, Fisch GS, dan Corby P. Toothbrush efficiacy for plaque removal. Int J Dent Hyg. 2014; 12(4): 251-256. doi: 10.1111/idh.12081
6. Kementerian Kesehatan RI. Laporan Nasional Riskesdas 2018. 2018. Diunduh dari www.
depkes.go.id pada 2 Desember 2019
7. Karadaglioglu OI, Ulusoy N, Baser KHC, Hanoglu A, Sik I. Aranntibacterial activities of herbal
toothpastes combined with essential oils against Streptococcus mutans. Pathogens. 2019; 8(1):
1-17. doi: 10.3390/pathogens8010020
8. Verma SK, Sharma N, Singh S, dan Razi MA. Comparison of different tooth brushes on the
degree of plaque removal. J Family Med Prim Care. 2020; 9(2): 556-560.
doi: 10.4103/jfmpc.jfmpc_666_19
9. Mangiri BS, Yani S, Anitasari S. Sari Buah Naga Super Merah (hylocereus costaricensis)
sebagai pewarna alami plak gigi. Jurnal Material Kedokteran Gigi. 2018; 7(1): 28-34.
doi: 10.32793/jmkg.v7i1.278.
10. Ladytama S, Nurhapsari A, Baehaqi M. Efektivitas larutan ekstrak jeruk nipis (citrus
aurantifolia) sebagai obat kumur terhadap penurunan indeks plak pada remaja usia 12
– 15 tahun - studi di SMP Nurul Islami, Mijen, Semarang. Odonto Dental Journal. 2014; 1(1):
39-43. doi: 10.30659/odj.1.1.39-43
11. British Dental Association. Motivation to brush for two minutes. Br Dent J. 2016; 22(5): 1.
doi: 10.1038/sj.bdj.2016.193
12. Datta D, Kumar SGR, Narayanan MBA, Selvamary AL, Sujatha A. Disclosing solutions
used in dentistry. World Journal of Pharmaceutical Research. 2017; 6(6): 1648-1656.
13. Fasoulas A, Pavlidou E, Petridis D, Mantzorou M, Seroglou K, Giaginis C. Detection of dental
plaque with disclosing agents in the context of preventive oral hygiene training programs.
Heliyon. 2019; 5(7): 1-8. doi: 10.1016/j.heliyon.2019.e02064
14. Haryani N, Mahmiyah E, Ayatullah DP. The use of turmeric (extracts and squeeze) to
detect plaque on teeth. Jurnal Info Kesehatan. 2019; 17(2): 169-175.
doi: 10.31965/infokes.Vol17.Iss2.276
15. Ratnaningsih DA, Nurilawaty V, Subiyandono. Extract Formulation and Effectiveness of
Beta vulgaris L. as dental plaque solution disclosing. International Journal of Medical
and Health Research. 2018; 4(2): 141-143.
16. Tumbel LK, Wowor PM, Siagian KV. Uji daya hambat minyak kelapa murni (virgin
coconut oil) terhadap pertumbuhan bakteri enterococcus faecalis. Jurnal e-GiGi (eG).
2017; 5(1): 100-105.
17. Susanto TD, Sujatno M, Kuswinarti, Yuwono HS. Efek antibakteri virgin coconut oil
terhadap methicillin resistant staphylococcus aureus. Medicinus. 2015; 4(8): 274-281.
18. Sari LNI, Fauziah E, Budiardjo, Suharsini M, Sutadi H, Indiarti IS, Rizal MF. Antibacterial
and antifungal effectiveness of virgin coconut oil (VCO) mousse against streptococcus
mutans and candida albicans biofilms. Journal of International Dental and Medical Research.
2019; 12(3):917-922.
19. Desseva I, Stoyanova M, Petkova N, Mihaylova D. Red beetroot juice phytochemicals bioaccessibility : an in vitro approach. Polish Journal of Food and Nutrition Science. 2020; 70 (1): 40-53.
20. Czyzowska A, Sieminowska K, Sniadowska M, Nowak A. Bioactive compounds and
microbial quality of stored fermented red beetroots and red beetroot juice. Pol. J. Food
Nutr. Sci. 2020; 70(1): 35–44.
21. Sarkar T, Sen MK, Nihar S. Extraction of natural pigment from beet root & proper packaging of
that red dye: a review. Journal of Agricultural Engineering and Food Technology. 2015; 2(2): 116-118.
22. Fatmasari D, Supriyana, dan Sukmawati. Larutan ubi jalar ungu dan buah bit sebagai
bahan identifikasi keberadaan plak gigi. Jurnal Kesehatan Gigi. 2014; 4(1): 19-24.
23. Baliga S, Muglika S, Kale R. Salivary pH: A diagnostic biomarker. Journal of Indian Society
of Periodontology. 2013; 17(4): 461-465.
24. Hidayah N, Hadijah D, dan Indrati. Ekstrak umbi bit (Beta vulgaris L.) sebagai bahan
pewarna plak. Jurnal Kedokteran Gigi Unpad. 2016; 28 (3): 15-19
25. Kunnika S, Pranee A. Influence of enzyme treatment on bioactive compounds and colour
stability of betacyanin in flesh and peel of red dragon fruit Hylocereus polyrhizus (Weber)
Britton and Rose. International Food Research Journal. 2011; 18(4): 1437-1448.
26. Chowdhary Z, Mohan R, Sharma V, Rai R, Das A. Disclosing agents in periodontics: an
Update. Journal of Dental College Azamgarh. 2015; 1(1): 103-110.
27. Olumese FE, Oboh HA. Toxicity study of beetroot (beta vulgaris) extract in normal
sprague dawley rats. NISEB Journal. 2017; 17(3): 125-133.
28. Saputra L, Gita, Dewi RS. Effect of 12.5% Virgin Coconut Oil (Cocos nucifera)
mouthwash on plaque index of fixed prosthetic denture users. International Journal of Applied
Pharmaceutics. 2017; 9(2): 41-44.
29. Rohman A, Irnawati, Erwanto Y, Lukitaningsih E, Rafi M, Fadzilah NA, Windarsih A, Sulaiman
A, Zakaria Z. Virgin coconut oil: extraction, physicochemical properties, biological activities and its authentication analysis. Food Reviews International. 2019; 1-21.
30. Miksusanti M, Herlinab H, Annuriac FN, Zulhijjahd Z. Patch film from celullose derivative incorporating with virgin coconut oil and its physical and antibacterial properties. Key Engineering Material. 2020; 840: 361-359.
31. Peedikayil FC, Remy V, John S, Chandru TP, Sreenivasan P, Bijapur GA. Comparison of antibacterial efficacy of coconut oil and chlorhexidine on Streptococcus mutans: An in vivo study. Journal of International Society of Preventive and Community Dentistry. 2016; 6: 447-452.
32. Peedikayil FC, Sreenivasan P, Narayanan A. Effect of coconut oil in plaque related
gingivitis-A preliminary report. Nigerian Medical Journal. 2015; 56(2): 143-149.
33. Kaushik M, Reddy P, Roshni, Dameshi PU, Mehra N, Marwaha A. The effect of coconut oil pulling on streptococcus mutans count in saliva in comparison with chlorhexidine mouthwash. The Journal of contemporary dental practice. 2016; 17(1): 38-41.
34. Lee JH, Jo YW. Antimicrobial effect of a lauric acid on streptococcus mutans biofilm. Annals
of International Medical and Dental Research. 2016; 2(4): 60-65.
35. Shino B, Peedikayil FC, Jaiprakas SR, Bijapur GA, Kottayi S, Jose D. Comparison of antimicrobial activity of chlorhexidine, coconut oil, probiotics, and ketoconazole on candida
albicans isolated in children with early childhood caries: an in vitro study. Scientifica.
2016: 1-6.
36. Sari M. The utilization of VCO (Virgin Coconut Oil) in manufacturing of solid soap with red
betel leaf extract addition (paper crotum ruiz & pav). Materials Science and Engineering.
2018; 1-7.
37. Sezgin Y, Ozgulb BM, Alptekin NO. Efficacy of oil pulling therapy with coconut oil on four-day
supragingival plaque growth: A randomized crossover clinical trial. Complementary Therapies in Medicine. 2019; 47: 1-6.
38. Seleem D, Chen E, Benso B, Pardi V, Murata RM. In vitro evaluation of antifungal activity of
monolaurin against Candida albicans biofilms. PeerJ. 2016; 1-17.
39. Tjin LD, Setiawan AS, Rachmawati E. Exposure time of virgin coconut oil agains oral Candida albicans. Padjajaran Journal of Dentistry. 2016; 28(2): 89-94.
40. Maesaroh I, Silviani S. Formulasi sediaan pasta gigi karbon aktif dengan basis virgin
coconut oil (VCO). Jurnal Ilmiah Manuntung. 2019; 5(1): 8-17.
41. Listyasari NA. Pengaruh pasta gigi dengan kandungan propolis terhadap pembentukan
plak gigi. Laporan Akhir Penelitian Fakultas Kedokteran Umum Universitas Diponegoro.
2012; 79-80.
DOI: https://doi.org/10.22146/mkgk.60758
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