Profil Penggunaan Obat Antihipertensi Pada Pasien Lanjut Usia Yang Dirawat Inap RS Akademik UGM

https://doi.org/10.22146/farmaseutik.v19i3.78446

Arina Titami(1), Chairun Wiedyaningsih(2*), I Dewa Putu Pratama(3)

(1) Magister Farmasi Klinik, Fakultas Farmasi, Universitas Gadjah Mada
(2) Universitas Gadjah Mada
(3) SMF Geriatri, RSUP Dr. Sardjito, Yogyakarta
(*) Corresponding Author

Abstract


Hypertension is a common disease that is simply defined as a persistent increase in arterial blood pressure. Elderly is correlated with increased blood pressure, which increases the risk of heart disease, stroke, and kidney disease. Intensive treatment of hypertension can significantly reduce the risk of heart and cerebral vascular disease, including target organ damage. This study is an observational study with a retrospective cohort design. The subjects in this study were elderly patients with a diagnosis of hypertension who were hospitalized at the Gadjah Mada University Academic Hospital (RSA UGM) Yogyakarta in the period January 1, 2021–December 31, 2021. The data in this study were sourced from the medical records of the UGM RSA. Data analysis was carried out descriptively to describe the profile of the use of antihypertensive drugs in elderly patients with a diagnosis of hypertension who were hospitalized. The number of patients in that period was found to be 534 patients and then 120 patients who met the inclusion criteria. The 60-69 years age group was the most patient group (71 patients). The proportion of women was more (73 patients) than men. The highest prevalence of comorbidities was diabetes as many as 29 patients. The highest prevalence of length of stay in hospital (LoS) is 1-5 days as many as 66 patients. In this study, the most common use of antihypertensive drugs in elderly patients with hypertension who were treated at UGM RSA was combination therapy (66 patients). Most patients used single therapy with calcium channel blocker (CCB) antihypertensive drugs, namely amlodipine as many as 24 patients and the most combination therapy was amlodipine and candesartan as many as 20 patients.


Keywords


elderly; hypertension; antihypertensive drugs

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References

1. DiPiro JT, Yee GC, Posey LM. Pharmacotherapy: A Pathophysiologic Approach, Eleventh Edition. McGraw Hill Professional; 2020.

2. Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018;39(33):3021-3104. doi:10.1093/eurheartj/ehy339

3. Hanif AAM, Shamim AA, Hossain MM, et al. Gender-specific prevalence and associated factors of hypertension among elderly Bangladeshi people: findings from a nationally representative cross-sectional survey. BMJ Open. 2021;11(1):e038326. doi:10.1136/bmjopen-2020-038326

4. Unger T, Borghi C, Charchar F, et al. 2020 International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension. 2020;75(6):1334-1357. doi:10.1161/HYPERTENSIONAHA.120.15026

5. Turana Y, Tengkawan J, Soenarta AA. Asian management of hypertension: Current status, home blood pressure, and specific concerns in Indonesia. J Clin Hypertens. 2020;22(3):483-485. doi:10.1111/jch.13681

6. Gurven M, Blackwell AD, Rodríguez DE, Stieglitz J, Kaplan H. Does Blood Pressure Inevitably Rise With Age? Hypertension. 2012;60(1):25-33. doi:10.1161/HYPERTENSIONAHA.111.189100

7. Baek H, Cho M, Kim S, Hwang H, Song M, Yoo S. Analysis of length of hospital stay using electronic health records: A statistical and data mining approach. PLoS One. 2018;13(4):e0195901. doi:10.1371/journal.pone.0195901

8. Javelin A, Sartika RAD. Hypertension as a common comorbidity in patients with diabetes: Occurrence based on eating habits and other determinants in Jakarta, Indonesia. Journal of International Dental and Medical Research. 2019;12(1):355-361.

9. James PA, Oparil S, Carter BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311(5):507-520. doi:10.1001/jama.2013.284427

10. Caballero-Gonzalez FJ. Calcium channel blockers in the management of hypertension in the elderly. Cardiovasc Hematol Agents Med Chem. 2015;12(3):160-165. doi:10.2174/1871525713666150310111554

11. Fajar DR, Fardin F, Dyka NF. Pola Penggunaan Obat Antihipertensi Pada Pasten Geriatri Rawat Jalan di Rumah Sakit TK. II Pelamonia Makassar Pada Bulan Januari-Maret talun 2019. Sasambo Journal of Pharmacy. 2020;1(1):22-25. doi:10.29303/sjp.v1i1.20



DOI: https://doi.org/10.22146/farmaseutik.v19i3.78446

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