Traditional Medicinal Plants for the Prevention and Treatment of Hypertension: A Literature Review

https://doi.org/10.22146/jmpf.89076

Athika Reza Febyanesti(1*), Bagoes Widjanarko(2), Zahroh Shaluhiyah(3)

(1) Master of Health Promotion, Faculty of Public Health, Diponegoro University, Semarang
(2) Faculty of Public Health, Diponegoro University, Semarang
(3) Faculty of Public Health, Diponegoro University, Semarang
(*) Corresponding Author

Abstract


Background: Hypertension is described as a disease that has a high prevalence in Indonesia. If it is not appropriately treated, it will cause advanced diseases such as stroke, heart failure, and kidney damage. Therefore, it is necessary to prevent and give early treatment, one of which is through alternative routine consumption of herbal medicines.

Objectives: This study aims to find out the benefits of herbal medicine for people with hypertension.

Methods: The method used in this research is a literature review. It is carried out in several stages by analyzing relevant previous pieces of literature using the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses) flowchart that illustrates the flow of information through the different phases of a systematic review.

Results: A total of 11 reviewed articles show that various herbal plants were obtained with multiple uses to reduce hypertension, and these plants were easy to get and use. It shows that the boiled leaves were the most frequently used part of the plant. Herbal treatment for hypertension aims to enrich antioxidants, block calcium channels, strengthen the endothelium, inhibit ACE, increase without production, and release and decrease biogenic amines. Herbal plants like lemongrass leaves, ginger, gotu kola leaves, and cat's whiskers are useful for lowering blood pressure levels in routine and intensive use without any side effect intervention by boiling.

Conclusion: Education regarding herbal plants for hypertension is also beneficial because the increased insight and knowledge they have reduced the possibility of hypertension occurring in the community


Keywords


Herbal plants; Hypertension; Prevention; Treatment

Full Text:

PDF


References

  1. Verma T, Sinha M, Bansal N, Yadav SR, Shah K, Chauhan NS. Plants Used as Antihypertensive. Nat Products Bioprospect. 2021;11(2):155-184. doi:10.1007/s13659-020-00281-x

  2. Ouedraogo WRC, Belemnaba L, Nitiéma M, et al. Phytochemical study, antioxidant and vasodilatation activities of leafy stem extracts of Flemingia faginea Guill. & Perr. (Barker), a medicinal plant used for the traditional treatment of arterial hypertension. Pharmacol Res - Mod Chinese Med. 2023;7(100231). doi:10.1016/j.prmcm.2023.100231

  3. Health Ministry of Indonesia. Hipertensi Penyakit Paling Banyak Diidap Masyarakat. Published 2019. Accessed August 11, 2023. https://sehatnegeriku.kemkes.go.id/baca/umum/20190517/5130282/hipertensi-penyakit-paling-banyak-diidap-masyarakat/

  4. Kementerian Kesehatan RI Badan Penelitian dan Pengembangan. Hasil Utama Riset Kesehatan Dasar. Kementrian Kesehat Republik Indones. Published online 2018:1-100. https://repository.badankebijakan.kemkes.go.id/id/eprint/3514/1/Laporan%20Riskesdas%202018%20Nasional.pdf

  5. Kementerian Kesehatan Republik Indonesia. Sepuluh Obat Anti Hipertensi. Published 2022. Accessed August 11, 2023. https://yankes.kemkes.go.id/view_artikel/1994/sepuluh-obat-anti-hipertensi

  6. Singh MP, Gohil KJ. Therapeuticefficacy andcost effectiveness ofherbal drugs–A reasonable approach. Pharmacol Res - Nat Prod. 2024;2(December 2023):100009. doi:10.1016/j.prenap.2023.100009

  7. Kamyab R, Namdar H, Torbati M, Ghojazadeh M, Araj-Khodaei M, Fazljou SMB. Medicinal plants in the treatment of hypertension: A review. Adv Pharm Bull. 2021;11(4):601-617. doi:10.34172/APB.2021.090

  8. Laristra T, Farida Y. Penggunaan Obat Herbal pada Pasien Hipertensi di Puskesmas Sibela Surakarta. Pros APC (Annual Pharm Conf. 2019;(March 2019):79-91. https://jurnal.uns.ac.id/Apc/Article/View/35613/23145

  9. Laouali N, Shah S, Macdonald CJ, et al. BMI in the Associations of Plant-Based Diets with Type 2 Diabetes and Hypertension Risks in Women: The E3N Prospective Cohort Study. J Nutr. 2021;151(9):2731-2740. doi:10.1093/jn/nxab158

  10. Faoziyah AR, Rahmah NN, Febriani L, et al. Pemanfaatan Tanaman Obat Sebagai Obat Tradisional sebagai Al ternatif Pengobatan Herbal Pasien Hipertensi dan Diabetes Mellitus. J Pengabdi Masy Al-Irsyad. 2019;I(2):63-71. Available online from: https://jpma.stikesalirsyadclp.ac.id/index.php/alirsyad/about/editorialTeam

  11. Ajeigbe OF, Oboh G, Ademosun AO. Ficus plants in the Co-management of Hypertension and Erectile dysfunction. Phytomedicine Plus. 2021;1(100096):100096. doi:10.1016/j.phyplu.2021.100096

  12. Aumeeruddy MZ, Mahomoodally MF. Traditional herbal therapies for hypertension: A systematic review of global ethnobotanical field studies. South African J Bot. 2020;135:451-464. doi:10.1016/j.sajb.2020.09.008

  13. Nurhidayati LG, Rejeki DS, Pramiastuti O, Murti FK. SOSIALISASI RAMUAN TANAMAN HERBAL UNTUK PENGOBATAN HIPERTENSI PADA MASYARAKAT DESA BLUBUK KECAMATAN DUKUHWARU KABUPATEN TEGAL. J-Abdi J Pengabdi Kpd Masy. 2023;2(10):6689-6694. doi:https://doi.org/10.53625/jabdi.v2i10.5194

  14. Mphuthi DD, Husaini DC. Traditional medicinal plants used by hypertensive patients in Belize: a qualitative evaluation of beliefs and practices. Bull Natl Res Cent. 2022;46(107). doi:10.1186/s42269-022-00789-x

  15. Septianingrum NMAN, Nurpalupi NR, Astuti ND, Hanafi MT, Setiawan SA. Pemanfaatan Terapi Herbal dan Pijat Akupresur Sebagai Pilihan Terapi Hipertensi pada Kelompok Lanjut Usia. Community Empower. 2020;5(3):129-137. doi:10.31603/ce.4351

  16. Al-anbaki M, Cavin A laure, Nogueira RC, et al. Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention. Plants. 2021;10(1018):1-12. doi:https://doi.org/10.3390/plants10051018

  17. Magalhães PKA, Araujo EN, Santos AM, et al. Ethnobotanical and ethnopharmacological study of medicinal plants used by a traditional community in Brazil’s northeastern. Brazilian J Biol. 2022;82:1-12. doi:10.1590/1519-6984.237642

  18. Handayani S, Malik A, Mufidah NI, et al. Ethnopharmacy Study of Herbal Medicine as Antihypertension in Simbang District. J Fitofarmaka Indones. 2022;9(3):7-12. doi:10.33096/jffi.v9i3.914

  19. Xue Z, Li Y, Zhou M, et al. Traditional Herbal Medicine Discovery for the Treatment and Prevention of Pulmonary Arterial Hypertension. Front Pharmacol. 2021;12(November):1-27. doi:10.3389/fphar.2021.720873

  20. Setiawati A, Immanuel H, Utami MT. The inhibition of Typhonium flagelliforme Lodd. Blume leaf extract on COX-2 expression of WiDr colon cancer cells. Asian Pac J Trop Biomed. 2016;6(3):251-255. doi:https://doi.org/10.1016/j.apjtb.2015.12.012

  21. Goit LN, Yang S. Treatment of Hypertension: A Review. Yangtze Med. 2019;03(02):101-123. doi:10.4236/ym.2019.32011

  22. Aatif M, Raza MA, El Oirdi M, et al. Bioassay-Guided Alkaloids Isolation from Camellia sinensis and Colchicum luteum: In Silico and In Vitro Evaluations for Protease Inhibition. Molecules. 2023;28(6). doi:10.3390/molecules28062459

  23. Bhattacharjee S, Elancheran R, Dutta K, Deb PK, Devi R. Cardioprotective potential of the antioxidant-rich bioactive fraction of Garcinia pedunculata Roxb. ex Buch.-Ham. against isoproterenol-induced myocardial infarction in Wistar rats. Front Pharmacol. 2022;13(October):1-21. doi:10.3389/fphar.2022.1009023

  24. Eff ARY, Rahayu ST, Mahayasih PG, Januarko MU. Standardization of Indonesian traditional antihypertensive medicines (JAMU) through the ACE inhibitor mechanism. Pharmacogn J. 2020;12(3):422-429. doi:10.5530/pj.2020.12.65

  25. Zuhrotun A, Hasanah AN, Sulistiyaningsih R. Edukasi Pemanfaatan Tumbuhan Berkhasiat Obat menjadi Sediaan Herbal. Media Karya Kesehat. 2020;3(2). doi:10.24198/mkk.v3i2.24887

  26. Nursiswati, Harun H, Andhika D. Social Media Campaign tentang Aktivitas Produksi dan Konsumsi Healthy Veggie Juice dalam Pencegahan Penyakit Kronis. Media Karya Kesehat. 2023;6(1):20-29. doi:10.24198/mkk.v6i1.42765



DOI: https://doi.org/10.22146/jmpf.89076

Article Metrics

Abstract views : 3 | views : 0

Refbacks

  • There are currently no refbacks.


Copyright (c) 2024 JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

©Jurnal Manajemen dan Pelayanan Farmasi
Faculty of Pharmacy
Universitas Gadjah Mada
Creative Commons License
View My Stats