Pengaruh Medication Therapy Management (MTM) terhadap Outcome Klinik dan Kualitas Hidup Pasien Hipertensi di Puskesmas Kota Yogyakarta

https://doi.org/10.22146/jmpf.58113

Tiara Dewi Salindri Pratama(1), Nanang Munif Yasin(2*), Susi Ari Kristina(3)

(1) Faculty of Pharmacy, Universitas Gadjah Mada
(2) Faculty of Pharmacy, Universitas Gadjah Mada
(3) Faculty of Pharmacy, Universitas Gadjah Mada
(*) Corresponding Author

Abstract


Medication therapy management (MTM), is a service model aimed at helping general health problems by preventing morbidity and mortality. Hypertension is a non-communicable disease which is a serious health problem which requires long-term therapy.  This study aims to see the effect of MTM on clinical Outcomes and quality of life of patients in hypertensive patients. This type of research is a quasi experimental one group with a pretest-posttest design. Analysis using paired sample t-test and Wilcoxon test with a significance used P <0,05. Respondents were 70 people, 67,1% were women. The characteristics of the majority age are 55-64 years with a percentage of 51,4%, the majority of education level is high school with 42,8%, non-civil servant jobs with a percentage of 45,7%, the length of diagnosis is dominated by 1-10 years (77,1%) and comorbidities diabetes mellitus occurred the most (10,0%). The results showed that the quality of life increased from before getting MTM 54,4 ± 8,9 and after MTM intervention 60,4 ± 6,6 (P value <0,001). Clinical outcome from systolic 159,2 ± 8,9 mmHg and diastolic 103,8 ± 8,0 mmHg before MTM to 144,1 ± 14,4 mmHg for systolic and 89,7 ± 8,8 mmHg for diastolic with p value <0,001 (p <0,05) for systolic blood pressure and p value: 0,016 (p <0,05) after receiving MTM intervention. Medication Therapy Management (MTM) has a significant influence on improving the quality of life and clinical Outcomes of hypertensive patients. The higher the quality of life of patients, blood pressure becomes more controlled.


Keywords


clinical outcome; hypertension; medication therapy management; quality of life; SF-36

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References

  1. Bolívar JJ. Essential Hypertension : An Approach to Its Etiology and Neurogenic Pathophysiology. Int J ofHypertension. Published online 2013.
  2. Al-tameemi NK, Sarriff A. Knowledge , attitude and practice of pharmacists on medication therapy management : a survey in Hospital Pulau. J Pharm Heal Care Sci. 2019;5(1):1-9.
  3. APA, Foundation NA of CDS. Medication therapy management in pharmacy practice: Core elements of an MTM service model (version 2.0). J Amarican Pharm Assoc. 2008;48(3):341-353.
  4. Viswanathan M, Kahwati LC, Golin CE, et al. Medication Therapy Management Interventions in Outpatient Settings A Systematic Review and Meta-analysis. 2015;175(1):76-87.
  5. Perlroth D, Packard M, Olinger L. Medication Therapy Management in Chronically Ill Populations : Final Report.; 2013.
  6. October E, Table C, Centers T, et al. Program Rujuk Balik Bagi Peserta JKN. Departemen Kesehatan Republik Indonesia. 2012;1(1):1-75.
  7. Dipiro JT, Talber RL, Yee GC, Matzke GR, Wells BG, Posey LM. 8th Edition Pharmacotherapy A Pathophysiologic Approach.; 2015.
  8. World Health Organization. A global brief on Hyper ­ tension World Health Day 2013. In: ; 2013.
  9. Anonim. Riset Kesehatan Dasar 2013. In: Kementerian Kesehatan Republik Indonesia. ; 2013.
  10. Anonim. Riset Kesehatan Dasar 2018. In: Kementerian Kesehatan Republik Indonesia. ; 2018.
  11. Flanagan S, Damery S, Combes G. The effectiveness of integrated care interventions in improving patient quality of life (QoL) for patients with chronic conditions. An overview of the systematic review evidence. Health Qual Life Outcomes. 2017;15(1):1-11.
  12. Ha NT, Duy HT, Le NH, Khanal V, Moorin R. Quality of life among people living with hypertension in a rural Vietnam community. BMC Public Health. 2014;14(1):1-9.
  13. Han SJ, Kim HK, Storfjell J, Kim MJ. Clinical outcomes and quality of life of home health care patients. Asian Nurs Res (Korean Soc Nurs Sci). 2013;7(2):53-60.
  14. Wittayanukorn S, Westrick SC, Hansen RA, et al. Evaluation of medication therapy management services for patients with cardiovascular disease in a self-insured employer health plan. J Manag Care Pharm. 2013;19(5):385-395.
  15. Billor N, Braxton-lloyd K, Fox BI, Garza KB. Evaluation of Medication Therapy Management Services for Patients with Cardiovascular Disease in a Self-Insured Employer Health Plan. J Manag Care Pharm. 2013;19(5).
  16. Rachmawati Y, Perwitasari DA, Adnan. Validasi Kuesioner Sf-36 Versi Indonesia Terhadap Pasien Hipertensi Di Puskesmas Yogyakarta. Pharmacy. 2014;11(01):14-25.
  17. Chua R, Keogh AM, Byth K, Loughlin AO. Comparison and validation of three measures of quality of life in patients with pulmonary hypertension. Intern Med J. 2006;36:705-710.
  18. Dos Santos RL, Da Silva FB, Ribeiro RF, Stefanon I. Sex hormones in the cardiovascular system. Horm Mol Biol Clin Investig. 2014;18(2):89-103.
  19. Wu JH, Wang SC, Lin LM. Mobile computing acceptance factors in the healthcare industry: A structural equation model. Int J Med Inform. 2007;76(1):66-77.
  20. Yoon SS, Burt V, Louis T, Carroll MD. Hypertension among adults in the United States, 2009-2010. NCHS Data Brief. 2012;(107):1-8.
  21. Yoon SS, Gu Q, Nwankwo T, Wright JD, Hong Y, Burt V. Trends in blood pressure among adults with hypertension United States, 2003 to 2012. Hypertension. 2015 ;65(1):54-61.
  22. Chajaee F, Pirzadeh A, Hasanzadeh A, Mostafavi F. Relationship between health literacy and knowledge among patients with hypertension in Isfahan province, Iran. Electron physician. 2018;10(3):6470-6477. doi:10.19082/6470
  23. Naser Ghasemi A, Peyman N, Tehrani H, et al. The Relationship of Health Literacy with Hypertension Self-Efficacy and General Self-Efficacy Among Schoolteachers. Mod Care J. 2018;15(4).
  24. Ramanath K V., Balaji DBSS, Nagakishore CH, Mahesh Kumar S, Bhanuprakash M. A study on impact of clinical pharmacist interventions on medication adherence and quality of life in rural hypertensive patients. J Young Pharm. 2012;4(2):95-100.
  25. De Boer IH, Bangalore S, Benetos A, et al. Diabetes and hypertension: A position statement by the American diabetes association. Diabetes Care. 2017;40(9):1273-1284.
  26. Lastra G, Syed S, Kurukulasuriya LR, Manrique C, Sowers JR. Type 2 diabetes mellitus and hypertension: An update. Endocrinol Metab Clin North Am. 2014;43(1):103-122.
  27. Ference BA, Ginsberg HN, Graham I, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement fromthe European Atherosclerosis Society Consensus Panel. Eur Heart J. 2017;38(32):2459-2472.
  28. Xiao M, Zhang F, Xiao N, Bu X, Tang X, Long Q. Health-related quality of life of hypertension patients: A population-based cross-sectional study in Chongqing, China. Int J Environ Res Public Health. 2019;16(13).
  29. Kaliyaperumal S, Hari SB, Siddela PK, Yadala S. Assessment of quality of life in hypertensive patients. J Appl Pharm Sci. 2016;6(5):143-147.

  30. Dennison-himmelfarb C, Handler J, Lackland DT. 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8). J Am Med Assoc. 2014;1097:1-14.




DOI: https://doi.org/10.22146/jmpf.58113

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