Penilaian Kualitas Hidup Pasien Hemodialisis Rutin dengan Anemia di Yogyakarta

https://doi.org/10.22146/jmpf.43187

Candra Eka Puspitasari(1*), Tri Murti Andayani(2), Fredie Irijanto(3)

(1) Study Program of Pharmacy, Faculty of Medicine, Mataram University
(2) Department of Pharmacology, Faculty of Pharmacy, Universitas Gadjah Mada
(3) Department of Kidney and Dialysis, Universitas Gadjah Mada Hospital
(*) Corresponding Author

Abstract


Anemia is often experienced by hemodialysis patients and can have an impact on the quality of life. This study aims to determine the effect of hemoglobin (Hb), hematocrit (Ht), and the characteristics and sociodemographic of the subjects on quality of life. The method used in this study was cross sectional and consecutive sampling technique. The data is retrieved by interviews which then analyzed using dummy multiple regression. Inclusion criteria included routine hemodialysis patients and did not receive blood transfusions. The validity and reliability test of the KDQoL-SF36 questionnaire showed reliable results. The results of the study on 112 subjects obtained an increase in Hb levels positively correlated with an increase in the KDQoL-SF36 score but not for an increase in Ht levels. Increased KDQoL-SF36 score illustrates the better quality of life of patients. Characteristics and sociodemography that influence quality of life include comorbid dummy hypertension-diabetes and work status. The condition of anemia can worsen the quality of life for hemodialysis patients.

Keywords


anemia; hemoglobin; hematocrit; quality of life; KDQoL-SF36

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References

1. Sadeghi M, Ebrahimi H, Abbasi M, Norouzadeh R. Relationship between anemia, quality of life, and laboratory indices in hemodialysis patients. Saudi J Kidney Dis Transpl. 2016;27(5):1063-1067. doi:10.4103/1319-2442.190905

2. Mikhali A, Brown C, Williams JA, et al. Clinical Practice Guideline Anaemia of Chronic Kidney Disease. Anaemia Chronic Kidney Dis. 2017;(June). www.nice.org.uk/accreditation.

3. Konsensus Manajemen Anemia Pada Pasien Gagal Ginjal Kronis. Jakarta: PERNEFRI; 2011.

4. Ayoub AMA. Quality of Life Among Dialysis Patients in United Arab Emirates. 2012.

5. Ron D. Hays, JOel D Kallich, Donna L Mapes, Stephen Joel Coons, Naseem Amin WBC and CK. Kidney Disease Quality of Life Short Form. Version 1.3. A Manual for Use and Scoring. Rand. 1997:1-39. doi:10.5747/cv2010.v02.n2.v032

6. De Goeij MCM, Meuleman Y, Van Dijk S, Grootendorst DC, Dekker FW, Halbesma N. Haemoglobin levels and health-related quality of life in young and elderly patients on specialized predialysis care. Nephrol Dial Transplant. 2014;29(7):1391-1398. doi:10.1093/ndt/gft533

7. Astrini WGA. Hubungan Kadar Hemoglobin, Indeks Masa Tubuh Dan Tekanan Darah Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisis Di RSUD Dokter Soedarso Pontianak April 2013. 2013;(April):1-9. http://jurnal.untan.ac.id/index.php/jfk/article/view/8095.

8. Setyaningrum N. Kajian Drug-Related Problems dan Gambaran Kualitas Hidup Pasien Hemodialisis Rutin Lanjut Usia di RSUP dr. Sardjito Yogyakarta. 2013.

9. Azwar S. Reliabilitas Dan Validitas. Edisi Keti. Yogyakarta: Pustaka Pelajar; 2011.

10. Azwar S. Penyusunan Skala Psikologi. Edisi Pert. Yogyakarta: Pustaka Pelajar; 2009.

11. Siregar S. Statistik Parametrik Untuk Penelitian Kuantitatif. Jakarta: Bumi Aksara; 2013.

12. Alsén P, Brink E. Fatigue after myocardial infarction - a two-year follow-up study. J Clin Nurs. 2013;22(11-12):1647-1652. doi:10.1111/jocn.12114

13. Artom M, Moss-Morris R, Caskey F, Chilcot J. Fatigue in advanced kidney disease. Kidney Int. 2014;86(3):497-505. doi:10.1038/ki.2014.86

14. Henfridsson P, Bengtsson M, Hugosson I, et al. Factors Related to Fatigue in Patients With Cirrhosis Before and After Liver Transplantation. Clin Gastroenterol Hepatol. 2011;10(2):174-181.e1. doi:10.1016/j.cgh.2011.07.029

15. Neugarten J, Acharya A, Silbiger SR. Effect of Gender on the Progression of Nondiabetic Renal Disease A Meta-Analysis. J Am Soc Nephrol. 2000;11(2):319-329.

16. Brunner L, Suddarth D. Buku Ajar Keperawatan Medical Bedah. 8th ed. Jakarta: EGC; 2002.

17. Murtisiwi L. Perbandingan Kualitas Hidup Paien Yang Menjalani Hemodialisis Dengan Terapi Epoetin Alfa Dan Epoetin Beta Di RS PKU Muhammadiyah Yogyakarta. Yogyakarta; 2015.

18. Dörhöfer L, Lammert A, Krane V, et al. Study design of DIACORE (DIAbetes COhoRtE) - a cohort study of patients with diabetes mellitus type 2. BMC Med Genet. 2013;14:25. doi:10.1186/1471-2350-14-25

19. Himmelfarb J, Ikizler TA. Hemodialysis. N Engl J Med. 2010;363(19):1833-1845. doi:10.1056/NEJMra0902710

20. Indonesian Renal Registry. Program Indonesian Renal Regestry (IRR). 2015:1-45.

21. Finkelstein FO, Story K, Firanek C, et al. Health-Related Quality of Life and Hemoglobin Levels in Chronic Kidney Disease Patients. Clin J Am Soc Nephrol. 2009;4(1):33-38. doi:10.2215/CJN.00630208

22. Wang L-J, Chen C-K. The Psychological Impact of Hemodialysis on Patients with Chronic Renal Failure. 2012. doi:DOI: 10.5772/36832

23. Kim K, Kang GW, Woo J. The quality of life of hemodialysis patients is affected not only by medical but also psychosocial factors: A canonical correlation study. J Korean Med Sci. 2018;33(14):1-11. doi:10.3346/jkms.2018.33.e111

24. Fryar CD, Gu Q, Ogden CL, et al. Association of frailty and physical function in patients with non-dialysis CKD: a systematic review. J Ren Nutr. 2013;2(6):1. doi:10.1186/1471-2369-14-228

25. Georgios T, Victoria A, Evangelos F, Savvas P, Sofia Z. Assessment of quality of life and fatigue among haemodialysis patients. Am J Nurs Sci. 2015;4(2-1):66-73.

26. Bohlke M, Nunes DL, Marini SS, Kitamura C, Andrade M, Von-Gysel MPO. Predictors of quality of life among patients on dialysis in southern Brazil. Sao Paulo Med J. 2008;126(5):252-256. doi:10.1590/S1516-31802008000500002

27. Lima MG, Barros MB de A, César CLG, Goldbaum M, Carandina L, Ciconelli RM. Health related quality of life among the elderly: a population-based study using SF-36 survey. Cad Saude Publica. 2009;25(10):2159-2167.

28. Khatib ST, Hemadneh MK, Hasan SA, Khazneh E, Zyoud SH. Quality of life in hemodialysis diabetic patients: A multicenter cross-sectional study from Palestine. BMC Nephrol. 2018;19(1):1-9. doi:10.1186/s12882-018-0849-x

29. Van KN, Duangpaeng S, Deenan A, Bonner A. Examining the health-related quality oflife of people v ^ ith end-stage kidney disease living in Hanoi , Vietnam. Ren Soc Australas J. 2012;8(3):140-145.

30. Moreno F, Sanz-Guajardo D, Lopez-Gomez JM, Jofre R, Valderrabano F. Increasing the hematocrit has a beneficial effect on quality of life and is safe in selected hemodialysis patients. J Am Soc Nephrol. 2000;11(2):335–342.

31. Parvan K, Lakdizaji S, Roshangar F, Mostofi M. Quality of sleep and its relationship to quality of life in hemodialysis patients. J caring Sci. 2013;2(4):295-304. doi:10.5681/jcs.2013.035



DOI: https://doi.org/10.22146/jmpf.43187

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