EVALUATION ON THE THERAPY APPROPRIATENESS AND ANTIHYPERTENSIVE AGENT SIDE EFFECTS TOWARD TYPE 2 DIABETES MELLITUS WITH CHRONIC KIDNEY DISEASE PATIENTS RECEIVING REGULAR HAEMODIALYSIS AT RSU PKU MUHAMMADIYAH YOGYAKARTA

https://doi.org/10.22146/jmpf.47

Fef Rukminingsih(1*), Djoko Wahyono(2), I Dewa Putu Pramantara(3)

(1) Akademi Farmasi Semarang
(2) Fakultas Farmasi Universitas Gadjah Mada Yogyakarta
(3) Poli Geriatri RSUP dr. Sardjito Yogyakarta
(*) Corresponding Author

Abstract


Antihypertensive selection accuracy determines the achievement of therapy target toward type 2 diabetes mellituswith chronic kidney disease patients who received regular hemodialysis treatment. The use of drugs in a longtimepotentially causes side effects and drug interactions as well.This research employed prospective observation by evaluating the appropriateness of therapy and monitoringdirectly the side effects of antihypertensive agent used toward type 2 diabetes mellitus with chronic kidney diseasepatients who received regular haemodialysis treatment at RSU PKU Muhammadiyah Yogyakarta during February– April 2011.For 42 patients having type 2 diabetes mellitus with chronic kidney disease who received regular haemodialysis treatment, it was found that patients who received appropriate therapy and achieved blood pressure therapy target was none, 4 patients (9.53%) received appropriate therapy yet the blood pressure remained uncontrolled, 2 patients(4.76%) received inappropriate therapy yet achieved controlled blood pressure and 36 patients (85.71%) receivedinappropriate therapy with remained uncontrolled blood pressure. From 42 patients, it was found that there were 11patients (26,20%) were possible and 5 patients (11,90%) were probable suffered from dry cough, 26 patients (61.91%) were possible for suffered from dizziness, 39 patients (92.86%) were possible suffered from headache, 2 patients (4.76%) were potentially suffered from fatigue and 13 patients (30,95%) were possible and 2 patients (4,76%) wereprobable suffered from drowsiness.

 

Keywords: antihypertensive, type 2 diabetes mellitus, haemodialysis


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DOI: https://doi.org/10.22146/jmpf.47

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