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Evaluasi Disfungsi Dasar Panggul Pasca Kemoradiasi pada Pasien Kanker Serviks Stadium Lanjut Lokal
https://doi.org/10.22146/jkr.81361 Pramana Pananja Putra(1*), Nuring Pangastuti †(2), Shinta Prawitasari(3)
(1) Departemen Obstetri dan Ginekologi, RSUD Majenang
(2) Departemen Obstetri dan Ginekologi, FKKMK UGM/RSUP Dr Sardjito, penulis telah meninggal dunia tanggal 24/7/2023
(3) Departemen Obstetri dan Ginekologi, FKKMK UGM/RSUP Dr Sardjito
(*) Corresponding Author
Abstract
Latar Belakang: Kanker serviks merupakan kanker kedua terbanyak pada perempuan dengan mortalitas 11,4%. Kemoradioterapi sebagai terapi utama stadium lanjut diketahui menyebabkan perubahan morfologi dan fungsi otot dasar panggul.
Tujuan: Mengevaluasi kejadian disfungsi dasar panggul pasca kemoradiasi pada pasien kanker serviks stadium lanjut lokal.
Metode: Penelitian kohort prospektif pada 50 pasien kanker serviks stadium IIB-IVB yang menjalani kemoradiasi di RSUP Dr Sardjito periode Juni 2021-Juni 2022. Evaluasi menggunakan kuesioner PFDI, MOS, dan perineometri.
Hasil dan Pembahasan: Prevalensi disfungsi dasar panggul meningkat dari 32% menjadi 74% pasca kemoradiasi. Terdapat peningkatan signifikan nilai PFDI (9,16 menjadi 24,58), penurunan MOS (3,92 menjadi 2,82), dan penurunan perineometri (11,21 menjadi 8,87) (p<0,05). Relative risk kemoradiasi terhadap disfungsi dasar panggul sebesar 1,62 (p<0,05).
Kesimpulan: Kemoradiasi meningkatkan prevalensi dan memperburuk gejala disfungsi dasar panggul pada pasien kanker serviks stadium lanjut lokal.
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DOI: https://doi.org/10.22146/jkr.81361
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