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Kadar Hormon LH Basal sebagai Prediktor Kebrhasilan Stimulasi Ovarium pada Program Bayi Tabung
https://doi.org/10.22146/jkr.37988 Dyah Ariantini(1*), Mohammad Lutfi(2), Diah Rumekti Hadiati(3)
(1) Departemen Obstetri dan Ginekologi, FK-KMK, UGM
(2) Departemen Obstetri dan Ginekologi, FK-KMK, UGM
(3) Departemen Obstetri dan Ginekologi, FK-KMK, UGM
(*) Corresponding Author
Abstract
Background: Ovarian stimulation is part of assisted reproductive technology (ART) process, which aims to spur the growth of follicles to be developed, so that it will increase the chance of getting pregnant. LH surge cause the final follicular maturation, ovulation and becoming corpus luteum. So that an increase in LH may adversely affect the development of the follicle and eventually affect in-vitro fertilization.
Objective To determine the effect of basal LH hormone to follicles on the stimulation of ovarian.
Method: Cohort Retrospective. Research Location: Permata Hati Clinic of Sardjito Hospital, Yogyakarta
Result dan Discussion: The study included 70 cycles of 70 women who underwent ovarian stimulation for in-vitro fertilization and fulfill inclusion and exclusion criterias. The subjects were divided into 2 groups based on basal LH hormone levels i.e. LH ≤ 3 mIU/ml as the test group and LH >3 mIU/ml as the control group. From analysis, response to ovarian stimulation in group with LH ≤3 mIU/ml was significantly different than LH >3 mIU/ml (RR 1,875; 95% CI 1,275–2,757; p=0,00*).
Conclusion: Low level of basal LH (≤ 3 mIU/ml) generating fewer number of mature follicles in patients who performed ovarian stimulation in in-vitro fertilization program.
Keyword: basal LH, ovarian stimulation, in-vitro fertilization.
Keywords
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Bullent, Bulbul Y, Onvutral A, Yorukogiu K, Posaci C, Demir N. 1999. Accuracy of Ovarian Reserve Test. Human reproduction, 15: 2822-2826
Speroff L, Glass RH, Kase NG. 1999. Clinical Gynecologic Endocrinologic and Infertility, 6th rev. ed. USA: Lippicott Williams & Wilkins, 1216-1234
Noci I, Biagiotti R, Maggi M, Ricci F, Cinotti A, Scarselli G. 2000. Effect of Low Day 3 Luteinizing Hormone Levels on in Vitro Fertilization Treatment Outcome. Gynecol Endocrinol, 14(5): 321-26.
Prasad S, Gupta T, Divya A. 2013. Correlation od the Day 3 FSH/LH Ratio and LH Concentration in Predicting IVF Outcome. J Reprod Infertil; 14(1): 2328
Sathya A, Balasubramanyam S, Gupta S, Verma T. 2010. Effect of body mass index on in vitro fertilization outcomes in women. J Hum Reprod Sci, 3(3):135-138.
Green BB, Weiss NS, Danling JR. 1988. Risk of ovulatory infertility in relation to body weight. Fertil Steril, 50:721–726.
McCormick B, Thomas M, Maxwell R, Williams D, Aubuchon M. 2008. Effects of polycystic ovarian syndrome on in vitro fertilization-embryo transfer outcomes are influenced by body mass index. Fertil Steril, 90(6): 2304-2309.
Karimzadeh MA, Ghandi S. 2009. Age and Basal FSH as a Predictor of ART Outcome. Iranian Journal of Reproductive Medicine, 7(1): 19-22
Toner, James P. 2011. Ovarian Reserve, Female Age and the Chance for Successful Pregnancy. Atlanta Center for Reproductive Medicine.
Frattarelli, Bergh, Drews. 2000.Evaluation of Basal Estradiol Levels in Assisted Reproductive Technology Cycles. Fertil Steril, 74(3): 518-24
Mukherjee T, Copperman AB, Lapinski R. 1996. An Elevated Day Three Follicle-Stimulating Hormone: Luteinizing Hormone Ratio (FSH:LH) the Presense of Normal Day 3 FSH Predict a Poor Response to Controlled Ovarian Hyperstimulation. Fertil steril, 65: 588-593
DOI: https://doi.org/10.22146/jkr.37988
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