Pengaruh L-Karnitin terhadap Kadar Lemak Daging dan Komposisi Tubuh Ikan Patin (Pangasius hypopthalmus)

Suwarsito Suwarsito(1*)

(1) Fakultas Perikanan dan Ilmu Kelautan Universitas Muhammadiyah Purwokerto
(*) Corresponding Author


This study was conducted to investigate the effect of dietary L-carnitine level on muscular lipid and body composition of asian catfish (Pangasius hypopthalmus). Four isoprotein and isocaloric diets with different levels of L-carnitine, 0.00% (diet K), 0.10% (diet A), 0.18% (diet B), and 0.29% (diet C) were applied in this experiment. Ten fishes with initial body weight of 35.86 ± 1.54 g were cultivated in each aquarium (water volume 60 l) for 50 days. Fishes were fed three times daily at satiation. The results showed that L-carnitine in the liver increased by increasing dietary L-carnitine level. While increasing dietary L-carnitine until 0.18% decreased content of lipid in the liver, but excessive dose of dietary L-carnitine increased content of lipid in the liver. It was further observed that L-carnitine in the diets reduced the muscular lipid content from 32.35 to 7.51% dry weight, but had no effect on body composition.


body composition, L-carnitine, muscular lipid, Pangasius hypopthalmus

Full Text:

Full Article (PDF)


Bell F.P., T.J. Vidmar, and T.L. Raymond. 1992. L-carnitine administration and withdrawal affect on plasma and hepatic carnitine concentrations, plasma lipid lipoprotein composition, and in vitro hepatic lipogenesis from labelled mevalonate and oleate in normal rabbits. J. Nutr. 122: 959-966.

Blanchard, G., B.M. Paragon, F. Milliat, and C. Lutton. 2002. Dietary L-carnitine supplementation in obese cats alters carnitine metabolism and decreases ketosis during fasting and induced hepatic lipidosis. J. Nutr. 132: 204-210.

Chatzifotis, S. and T. Takeuchi. 1997. Effect of supplemental carnitine on body weight loss, proximate and lipid compositions and carnitine content of Red Sea Bream (Pagrus major) during starvation. Aquaculture. 158:129-140.

Chatzifotis, S., T. Takeuchi, and T. Seikai. 1996. The effect of carnitine supplementation on growth of Red Sea Bream (Pagrus major) fingerlings at two levels of dietary lysine. Aquaculture. 147: 235-248.

Furuichi, M. 1988. Dietary requirement. In: Fish nutrition and mariculture. T. Watanabe (Ed.). Japan International Cooperation Agency. Tokyo: 8-78.

Greenwood, R.H., E.C. Titgemeyer, G.L. Stokka, J.S. Drouillard, and C.A. Loest. 2001. Effects of L-carnitine on nitrogen retention and blood metabolites of growing steers and performance of finishing steers. J. Anim. Sci. 79 : 254-260.

Groth, A., U. Focken, R.M. Coloso, and K. Becker. 1998. Effect of L-carnitine on growth, survival and body composition of individually reared juvenile Tiger Shrimp (Penaeus monodon, Fab.).agroth/ag 1998. Diakses tanggal 15 Januari 2003.

Heo, K., J. Odle, I.K. Han, W. Cho, S. Seo, E.V. Heugten, and D. H. Pilkington. 2001. Dietary L-carnitine improves nitrogen utilization in growing pigs fed low energy, fat-containing diets. J. Nutr. 130: 1809-1814.

Hurot, J.M., M. Cucherat, M. Haugh, and D. Fouque. 2002. Effects of L-carnitine supplementation in maintenance hemodialysis patients: a systematic review. J. Am. Soc. Nephrol. 13: 708-714.

Ji, H., T.M. Bradley, and G.C. Tremblay. 1996. Atlantic Salmon (Salmon salar) fed L-carnitine exhibit altered intermediary metabolism and reduced tissue lipid, but no change in growth rate. J. Nutr. 126: 1937-1950.

Mattjik, A.A dan M. Sumertajaya. 2000. Perancangan percobaan dengan aplikasi SAS dan Minitab Jilid I. IPB Press. Bogor. 326 p.

Miyasaki, T., M. Sato, R. Yoshinaka, and M. Sagaguchi. 1994. Determination of free and esterified carnitine in tissues of rainbow trout by high performance liquid chromatography. Fish. Sci. 60: 225-227.

Owen, K.Q., H. Ji, C.V. Maxwell, J.L. Nelssen, R.D. Goodband, M.D. Tokach, G.C. Tremblay, and S.I. Koo. 2001. Dietary L-carnitine suppresses mitochondrial branched-chain keto acid dehydrogenase activity and enhances protein accretion and carcass characteristics of swine. J. Anim. Sci. 79: 3104-3112.

Rodehutscord, M. 1995. Effects of supplemental dietary L-carnitine on growth and body composition of rainbow trout (Oncorhynchus mykiss) fed high-fat diets. J. Anim. Physiol. Anim. Nutr. 73: 276-279

Santulli, A. and V. D’Amelio. 1986. Effects of supplemental dietary carnitine on growth and lipid metabolism of hatchery-reared Sea Bass (Dicentrarchus labrax, L). Aquaculture. 59: 177-186.

Supadmo. 1997. Pengaruh sumber khitin dan prekursor karnitin serta minyak ikan lemuru terhadap kadar lemak dan kolesterol serta asam lemak omega-3 ayam broiler. Disertasi Program Pascasarjana IPB. Bogor: 217 p.

Takeuchi, T. 1988. Laboratory work chemical evaluation of dietary nutrient. In : Fish Nutrition and mariculture. T. Watanabe (Ed.). Kanagawa Fisheries Training Center, Japan International Cooperation Agency. Tokyo: 179-232.

Vaz, F.M., B. Melegh, J. Bene, D. Cuebas, D.A. Gace, A. Bootsma, P. Vreken, A.H.V. Gennip, L.L. Biebir, and R.J.A. Wanders. 2002. Analysis of carnitine biosynthesis metabolites in urine by HPLC-electrospray tandem mass spectrometry. Clin. Chem. 48(6): 826-834.


Article Metrics

Abstract views : 2111 | views : 4911


  • There are currently no refbacks.

Copyright (c)

Jurnal Perikanan Universitas Gadjah Mada (print ISSN 0853-6384; online ISSN 2502-5066) is published by Department of Fisheries, Universitas Gadjah Mada in collaboration with Semnaskan UGM (Seminar Nasional Tahunan Hasil Perikanan dan Kelautan) and ISMFR (International Symposium on Marine and Fisheries Research).


View My Stats