Perbandingan kadar merkuri, kreatinin, dan urea pada pekerja industri di Kotagede dan Banguntapan, Yogyakarta sebagai indikator pencemaran

https://doi.org/10.22146/jcoemph.42654

Pramudji Hastuti(1*), Sri Sutarni(2)

(1) Departemen Biokimia Fakultas Kedokteran, Kesehatan Masyarakat, dan Keperawatan, Universitas Gadjah Mada, Yogyakarta, Indonesia
(2) Departemen Ilmu Penyakit Syaraf, Fakultas Kedokteran, Kesehatan Masyarakat, dan Keperawatan, Universitas Gadjah Mada, Yogyakarta, Indonesia
(*) Corresponding Author

Abstract


Study from the Environmental Office of Yogyakarta, indicates in Kotagede found the pollution of mercury from the environment because of improper disposal of wastewater. This study aims to assess the levels of mercury, creatinine and urea in the serum and urine of people working in several industries in Kotagede and Banguntapan. Subjects of this study were 52 employees in several industries in Kotagede Yogyakarta with a range of ages between 20 - 71 years and length of work between 3 - 38 years. A total of 42 people with the age range was 21 - 63 years and the length of work between 1 - 20 years were taken from industrial employees in Bantul who have almost the same geographical conditions as Kotagede. Determination of mercury levels using the Atomic Absorption Spectrophotometry (AAS) method while the determination of urea and creatinine levels by a Dyasis kit. In Kotagede, there were 3 people (5.8%) with the average mercury serum of 0.217 ppb and no mercury in the urine was found in all subjects. In Banguntapan, one person (2.4%) had 0.200 ppb mercury serum and 6 people (14.3%) had an average mercury urine level of 0.395 ppb. Urine creatinine and urea levels in subjects from Kotagede were higher than those from Banguntapan (p<0.05), despite being on the normal range. The presence of mercury in several industrial employees in Kotagede and Banguntapan is still on the low range even though it was correlated to creatinine levels.

Keywords


creatinin; mercury; toxicity; urea

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References

  1. Subagio OMR, Budiati SR. Pengaruh keberadaan industri kerajinan perak terhadap penyerapan tenaga kerja dan pendapatan pekerja di Kecamatan Kotagede Yogyakarta. Jurnal Bumi Indonesia. 2013;2(2):68-77
  2. Sutarni S. Toksisitas merkuri sebagai faktor risiko epilepsi anak. Berita Kedokteran Masyarakat. 2005;21(5)
  3. Park J and ZhengW, 2012, Human Exposure and Health Effects of Inorganic and Elemental Mercury. J Prev Med Public Health. 2012;45(6): 344–352.
  4. Salthammer T, Uhde E, Omelan A, Ludecke A, Moriske HJ. Estimating human indoor exposure to elemental mercury from broken compact fluorescent lamps (CFLs) Indoor Air. 2012;22:289–98.
  5. Risher J, Amler S. Mercury exposure: evaluation and intervention the inappropriate use of chelating agents in the diagnosis and treatment of putative mercury poisoning. Neurotoxicology. 2005;26(4): 691–699
  6. Nayfeh A, Kassim T, Addasi N, Alghoula F, Holewinski C, Depew Z. A Challenging Case of Acute Mercury Toxicity. Case reports in medicine. 2018;2018 Article ID 1010678, 4 pages
  7. Bjørklund G, Dadar M, Mutter J, Aaseth J. The toxicology of mercury: Current research and emerging trends. Environ Res. 2017; 159:545-554.
  8. Orr S, Bridges C. Chronic kidney disease and exposure to nephrotoxic metals. Int J Mol Sci. 2017 May;18(5):1039.
  9. Pollack AZ, Mumford SL, Mendola P, Perkins NJ, Rotman Y, Wactawski-Wende J et al. Kidney biomarkers associated with blood lead, mercury, and cadmium in premenopausal women: a prospective cohort study. J Toxicol Environ Health. 2015 Jan 17;78(2):119-31.
  10. Liu J, Goyer RA, Waalkes MP. Toxic effects of metals. In: Casarett LJ, Klaassen CD, editors. Casarett and Doull’s toxicology: The basic science of poisons. 7th ed. McGraw-Hill, New York: McGraw-Hill; 2008.
  11. Suara Merdeka. Kotagede terancam Minamata [Internet]. Jawa Tengah: Suara Merdeka; 2004 [cited 2019 Jan 10]. Available from: http://www.suaramerdeka.com/harian/04010/20/nas14.htm
  12. Sekarwati N, Murachman B, Sunarto. Dampak logam berat Cu (tembaga) dan Ag (Perak) pada limbah cair industri perak terhadap kualitas air sumur dan kesehatan masyarakat serta upaya pengendaliannya di Kotagede Yogyakarta. Jurnal Ekosains. 2015;7(1):64-76
  13. Langgeng Wahyu S, Murti SH. Kajian kerusakan lingkungan perairan sungai akibat aktivitas industri di Kecamatan Banguntapan Kabupaten Bantul [master’s thesis]. Yogyakarta: Universitas Gadjah Mada; 2016.
  14. Weber C. An overview of blood pressure and aging, what happens to blood pressure as we age? Verywell Health; 2018 [updated 2018 Dec 9; cited 2019 Jan 10]. Available from: https://www.verywellhealth.com/what-happens-to-blood-pressure-as-we-age-1763944
  15. Sandilands EA, Dhaun N, Dear JW, Webb DJ. Measurement of renal function in patients with chronic kidney disease. Br J Clin Pharmacol. 2013;76(4): 504–515
  16. Clarkson TW, Magos L. The toxicology of mercury and its chemical compounds. Crit Rev Toxicol. 2006; 36(8): 609–662.
  17. Davidson J. Mercury testing: Fact Sheet. June 2010, Auckland City Hospital: Labplus.
  18. Diner B, Brenner B. Toxicity of mercury: Treatment of mercury intoxication [Internet]. Emedicine-The instant acess to the minds of medicine; 2001 [updated 2018 Nov 5; cited 2019 Jan 10]. Available from: http://www.emedicine.com/ emerg/topic813.htm
  19. Ferguson SA, Smith M, Sullivan M, Keazer L, Lyon S, Childress A et al. 2002, Monitoring mercury exposure [Internet]. 2002 [cited 2019 Jan 10]. Available from: http:/danpatch.eca.purdue.edu/~epados / mercbuild/scr/credits.htm.
  20. Ye BJ, Kim BG, Jeon MJ, Kim SY, Kim HC, Jang TW et al. Evaluation of mercury exposure level, clinical diagnosis and treatment for mercury intoxication. Ann Occup Environ Med. 2016 Dec;28(1):5.



DOI: https://doi.org/10.22146/jcoemph.42654

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