Gambaran klinis, MRI kepala dan sitologi cairan serebrospinal pada pasien metastasis leptomeningeal
https://doi.org/10.22146/bns.v18i2.54985 Kusumo Dananjoyo(1*), Rusdy Ghazali Malueka(2), Ahmad Asmedi(3)
(1) Departemen Neurologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
(2) Departemen Neurologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
(3) Departemen Neurologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author
Abstract
Metastasis leptomeningeal (ML) merupakan kondisi yang berbahaya pada kasus neuroonkologi dan masih menjadi tantangan dalam diagnosis, manajemen, dan prognosis. ML merupakan salah satu komplikasi di bidang neuroonkologi namun diagnosis kasus ini masih sering tidak terdiagnosis. Insidensi ML pada tumor padat sekitar 4-5% dan mencapai 20% pada keganasan hematologi. Penegakan diagnosis ML masih menjadi tantangan karena tanda dan gejala yang tidak spesifik sedangkan imaging memiliki sensitivitas dan spesifisitas yang bervariasi.
Artikel ini bertujuan untuk memberikan informasi mengenai gambaran klinis, MRI kepala dan analisis LCS dan pemeriksaan molekuler lainnya untuk menegakkan diagnosis ML, sehingga neurologis dapat mendiagnosis ML dan melakukan pemeriksaan selanjutnya agar terapi maksimal.
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DOI: https://doi.org/10.22146/bns.v18i2.54985
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