Faktor-faktor yang berhubungan dengan kejadian kanker serviks di rumah sakit Sardjito Yogyakarta

Dwi Putri Sulistiya; Dibyo Pramono; Detty Nurdiati

doi:10.22146/bkm.17160

Faktor-faktor yang berhubungan dengan kejadian kanker serviks di rumah sakit Sardjito Yogyakarta

https://doi.org/10.22146/bkm.17160

Dwi Putri Sulistiya^(1*), Dibyo Pramono⁽²⁾, Detty Nurdiati⁽³⁾

(1) Departemen Biostatistik, Epidemiologi dan Kesehatan Populasi, Fakultas Kedokteran, Universitas Gadjah Mada
(2) Departemen Kedokteran Gigi dan Pencegahan, Fakultas Kedokteran Gigi, Universitas Gadjah Mada
(3) Departemen Obstetrik dan Ginekologi, Fakultas Kedokteran, Universitas Gadjah Mada/RSUP Dr. Sardjito
(*) Corresponding Author

Abstract

Related factors for cervical cancer incidence in Dr. Sardjito Hospital in Yogyakarta

Purpose

This study aimed to determine the factors associated with the incidence of cervical cancer in Dr. Sardjito Hospital.

Methods

A case control study was conducted from July to October 2016. A total of 105 cases and 105 controls were included in the study. Cases were patients suffering from cervical cancer based on doctor's diagnosis, and controls were patients who do not have cervical cancer. Sampling was done by consecutive sampling technique. Data were analyzed by chi-square and logistic regression tests.

Results

Factors associated with incidence of cervical cancer in Sardjito hospital were the first age variable for sexual intercourse ≤ 20 years with aOR of 2.41 (95% CI: 1.35-4,29; p=0.003) and use of oral contraceptive/pill with aOR of 3.40 (95% CI: 1.46-7.92; p=0.004), while the number of pairs, parities, pads, circumcision and smoking were not associated with the incidence of cervical cancer.

Conclusion

Women who have not been sexually active can vaccinate for HPV. Also, they need to use condoms when having sex. Women aged 30-49 years (sexually active) are expected to be able to follow the early detection program of cervical cancer with visual inspection method of acetic acid which can now be done in health centers and have a pap smear examination at least once a year.

Keywords

cervical cancer; case control

Full Text:

PDF (Bahasa Indonesia)

References

Kemenkes RI. Panduan Program Nasional Gerakan Pencegahan dan Deteksi Dini Kanker: Kanker Leher Rahim dan Kanker Payudara. Jakarta; 2015.
Kemenkes RI. Panduan Nasional Penanganan Kanker, Kanker Serviks. Komite Nasional Penanggulangan Kanker (KPKN). Jakarta; 2015.
Globocan. Cancer fact Street: Cervical cancer incidence and mortality worldwide in 2012 [Internet]. 2012 [cited 2015 Sep 12]. Available from: http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx
Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015 Mar 1;136(5).
Kemenkes RI. Pusat data dan Informasi Kementerian Kesehatan RI. Jakarta; 2015.
CDPH (California Department of Health Care Services & California Department of Public Health). Cancer of the cervix [Internet]. 2013. Available from: www.dhcs.ca.gov/services/
Ferrera A, Velema JP, Figueroa M, Bulnes R, Toro LA, Claros JM, et al. Co-factors related to the causal relationship between human papillomavirus and invasive cervical cancer in Honduras. Int J Epidemiol. 2000 Oct;29(5):817–25.
Kapeu AS, Luostarinen T, Jellum E, Dillner J, Hakama M, Koskela P, et al. Is Smoking an Independent Risk Factor for Invasive Cervical Cancer? A Nested Case-Control Study Within Nordic Biobanks. Am J Epidemiol. 2008 Dec 13;169(4):480–8.
Louie KS, de Sanjose S, Diaz M, Castellsagu? X, Herrero R, Meijer CJ, et al. Early age at first sexual intercourse and early pregnancy are risk factors for cervical cancer in developing countries. Br J Cancer. 2009 Apr 7;100(7):1191–7.
Tira DS. Risiko jumlah perkawinan, riwayat abortus, dan pemakaian alat kontrasepsi hormonal terhadap kejadian kanker serviks di Rumah Sakit Pelamonia Makassar Tahun 2006-2007. MKM. 2008;3(1).
Syatriani S. Faktor Risiko Kanker Serviks di Rumah Sakit Umum Pemerintah Dr. Wahidin Sudirohusodo Makassar, Sulawesi Selatan. Kesmas Natl Public Heal J. 2011 Jun 1;5(6).
Sankaranarayanan R. Cervical cancer in developing countries. Trans R Soc Trop Med Hyg. 2002 Nov;96(6):580–5.
Rasjidi I. Epidemiologi Kanker Serviks. Indones J Cancer. 2009;3(3).
Umri S. Hubungan Usia Pertama Kali Melakukan Hubungan Seks dengan Kejadian Kanker Serviks di Rumah Sakit Haji Adam Malik Medan. Universitas Gadjah Mada; 2014.
Setyarini E. Faktor-Faktor Yang Berhubungan Dengan Kejadian Kanker Leher Rahim Di RSUD DR Moewardi Surakarta. Universitas Muhammadiyah Surakarta; 2009.
Karimi Zarchi M, Akhavan A, Gholami H, Dehghani A, Naghshi M, Mohseni F. Evaluation of cervical cancer risk-factors in women referred to Yazd-Iran hospitals from 2002 to 2009. Asian Pac J Cancer Prev. 2010;11(2):537–8.
B. P, Sungkar S. Penggunaan Vaksin Human Papilloma virus Dalam Pencegahan Kanker Serviks. Maj Kedokt Indones. 2007;57(11).
BPS. Analisis Data Perkawinan Usia Anak Di Indonesia. Jakarta; 2016.
BPS, BKKBN. Indonesia Demographic and Health Survey 2012 Statistics Indonesia National Population and Family Planning Board Ministry of Health MEASURE DHS ICF International. Jakarta; 2013.
Moreno V, Bosch FX, Muñoz N, Meijer CJ, Shah K V, Walboomers JM, et al. Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric case-control study. Lancet. 2002 Mar 30;359(9312):1085–92.
Khasbiyah. Beberapa faktor risiko kanker serviks uteri (studi pada penderita kanker serviks uteri di rumah sakit dr. Kariadi Semarang pada bulan Agustus-September 2004). Universitas Diponegoro; 2004.